{"title":"30C砷在德里隔离区居民预防COVID-19的有效性——一项前瞻性、社区、平行队列研究","authors":"Debadatta Nayak, Karanpreet Nahar, Rupali Bhalerao, Lovepreet Kaur, Tabassum Parveen, Ruchika Bhalla, James Michael, Swati Sharma, Parul Singh, Afsana Jainab, Hanuman Ram, Abhishek Chaudhuri, Ummesalma Parvin, Nidhi Jain, Anil Khurana","doi":"10.1055/s-0042-1745755","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This work was undertaken to evaluate the protective effect of <i>Arsenicum album</i> 30C against COVID-19.</p><p><strong>Design: </strong>The work was designed as a prospective parallel cluster cohort study.</p><p><strong>Intervention: </strong>Participants were enrolled in a homeopathy intervention (HI) cohort (who received <i>Arsenicum album</i>) or in a non-intervention (NI) cohort (who received no systematic intervention) from COVID-19 containment areas of Delhi. Individuals of age 5 years or above were given four medicated pills of <i>Arsenicum album</i> 30C, while those from 1 to 5 years old were given two medicated pills in each dose.</p><p><strong>Results: </strong>The analysis included 10,180 individuals residing in 11 COVID-19 containment areas in Delhi, out of which 6,590 individuals were in the HI cohort and 3,590 individuals were in the NI cohort. The overall protective effect of <i>Arsenicum album</i> 30C was 83.43% (95% confidence interval [CI], 76.77 to 88.17): 45 cases per 6,590 (8.34 per 10,000 person-weeks) in the <i>Arsenicum album</i> 30C group versus 143 cases per 3,590 (45.01 per 10,000 person-weeks) in the NI cohort. The protective effect of <i>Arsenicum album</i> 30C against laboratory confirmed COVID-19 was 74.40% (95% CI, 55.08 to 85.41): 18 cases per 6,590 (3.32 per 10,000 person-weeks) in the <i>Arsenicum album</i> 30C group versus 38 cases per 3,590 (11.85 per 10,000 person-weeks) in the NI cohort.</p><p><strong>Conclusion: </strong>The use of <i>Arsenicum album</i> 30C was associated with some protection against probable and laboratory-confirmed COVID-19 in a containment-zone setting. Randomized controlled trials are needed to confirm or refute these results.</p>","PeriodicalId":13227,"journal":{"name":"Homeopathy","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Effectiveness of Arsenicum album 30C in Prevention of COVID-19 in Individuals Residing in Containment Zones of Delhi-A Prospective, Community-based, Parallel Cohort Study.\",\"authors\":\"Debadatta Nayak, Karanpreet Nahar, Rupali Bhalerao, Lovepreet Kaur, Tabassum Parveen, Ruchika Bhalla, James Michael, Swati Sharma, Parul Singh, Afsana Jainab, Hanuman Ram, Abhishek Chaudhuri, Ummesalma Parvin, Nidhi Jain, Anil Khurana\",\"doi\":\"10.1055/s-0042-1745755\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This work was undertaken to evaluate the protective effect of <i>Arsenicum album</i> 30C against COVID-19.</p><p><strong>Design: </strong>The work was designed as a prospective parallel cluster cohort study.</p><p><strong>Intervention: </strong>Participants were enrolled in a homeopathy intervention (HI) cohort (who received <i>Arsenicum album</i>) or in a non-intervention (NI) cohort (who received no systematic intervention) from COVID-19 containment areas of Delhi. Individuals of age 5 years or above were given four medicated pills of <i>Arsenicum album</i> 30C, while those from 1 to 5 years old were given two medicated pills in each dose.</p><p><strong>Results: </strong>The analysis included 10,180 individuals residing in 11 COVID-19 containment areas in Delhi, out of which 6,590 individuals were in the HI cohort and 3,590 individuals were in the NI cohort. The overall protective effect of <i>Arsenicum album</i> 30C was 83.43% (95% confidence interval [CI], 76.77 to 88.17): 45 cases per 6,590 (8.34 per 10,000 person-weeks) in the <i>Arsenicum album</i> 30C group versus 143 cases per 3,590 (45.01 per 10,000 person-weeks) in the NI cohort. The protective effect of <i>Arsenicum album</i> 30C against laboratory confirmed COVID-19 was 74.40% (95% CI, 55.08 to 85.41): 18 cases per 6,590 (3.32 per 10,000 person-weeks) in the <i>Arsenicum album</i> 30C group versus 38 cases per 3,590 (11.85 per 10,000 person-weeks) in the NI cohort.</p><p><strong>Conclusion: </strong>The use of <i>Arsenicum album</i> 30C was associated with some protection against probable and laboratory-confirmed COVID-19 in a containment-zone setting. Randomized controlled trials are needed to confirm or refute these results.</p>\",\"PeriodicalId\":13227,\"journal\":{\"name\":\"Homeopathy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2022-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Homeopathy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0042-1745755\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Homeopathy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/s-0042-1745755","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 7
摘要
目的:评价Arsenicum album 30C对COVID-19的保护作用。设计:本研究设计为前瞻性平行集群队列研究。干预:参与者被纳入来自德里COVID-19防控区域的顺势疗法干预(HI)队列(接受Arsenicum相册)或非干预(NI)队列(未接受系统干预)。年龄在5岁及以上的个体给予4粒Arsenicum album 30C, 1 ~ 5岁的个体给予每剂2粒。结果:该分析包括居住在德里11个COVID-19控制区的10180人，其中6590人属于HI队列，3590人属于NI队列。Arsenicum album 30C的总体保护效果为83.43%(95%可信区间[CI]， 76.77至88.17):Arsenicum album 30C组为45例/ 6590(8.34 / 10000人周)，NI组为143例/ 3590(45.01 / 10000人周)。Arsenicum album 30C对实验室确诊的COVID-19的保护作用为74.40% (95% CI, 55.08至85.41):Arsenicum album 30C组每6590例(3.32 / 10000人周)有18例，NI组每3590例(11.85 / 10000人周)有38例。结论:在隔离区环境中，使用Arsenicum album 30C可在一定程度上防范可能的和实验室确诊的COVID-19。需要随机对照试验来证实或反驳这些结果。
Effectiveness of Arsenicum album 30C in Prevention of COVID-19 in Individuals Residing in Containment Zones of Delhi-A Prospective, Community-based, Parallel Cohort Study.
Objective: This work was undertaken to evaluate the protective effect of Arsenicum album 30C against COVID-19.
Design: The work was designed as a prospective parallel cluster cohort study.
Intervention: Participants were enrolled in a homeopathy intervention (HI) cohort (who received Arsenicum album) or in a non-intervention (NI) cohort (who received no systematic intervention) from COVID-19 containment areas of Delhi. Individuals of age 5 years or above were given four medicated pills of Arsenicum album 30C, while those from 1 to 5 years old were given two medicated pills in each dose.
Results: The analysis included 10,180 individuals residing in 11 COVID-19 containment areas in Delhi, out of which 6,590 individuals were in the HI cohort and 3,590 individuals were in the NI cohort. The overall protective effect of Arsenicum album 30C was 83.43% (95% confidence interval [CI], 76.77 to 88.17): 45 cases per 6,590 (8.34 per 10,000 person-weeks) in the Arsenicum album 30C group versus 143 cases per 3,590 (45.01 per 10,000 person-weeks) in the NI cohort. The protective effect of Arsenicum album 30C against laboratory confirmed COVID-19 was 74.40% (95% CI, 55.08 to 85.41): 18 cases per 6,590 (3.32 per 10,000 person-weeks) in the Arsenicum album 30C group versus 38 cases per 3,590 (11.85 per 10,000 person-weeks) in the NI cohort.
Conclusion: The use of Arsenicum album 30C was associated with some protection against probable and laboratory-confirmed COVID-19 in a containment-zone setting. Randomized controlled trials are needed to confirm or refute these results.
期刊介绍：
Homeopathy is an international peer-reviewed journal aimed at improving the fundamental understanding and clinical practice of homeopathy by publishing relevant high-quality original research articles, reviews, and case reports. It also promotes commentary and debate on matters of topical interest in homeopathy.
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