恶性软组织肿瘤切除术中的感染发生率和风险:来自全国软组织肿瘤登记处的数据

IF 1.5 4区 医学 Q3 ORTHOPEDICS
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引用次数: 0

摘要

背景术后感染是恶性软组织肿瘤肢体救治手术中的一种破坏性并发症。这些罕见癌症的绝对病例数较低,是数据收集和分析的瓶颈。方法从日本骨与软组织肿瘤登记处提取恶性软组织肿瘤切除术的数据。结果 共纳入 14,460 例病例。感染发生率为 2.6%。感染的重要风险因素包括:男性、下肢或躯干位置、肿瘤直径超过 10 厘米、跨腔侵犯、高级别、自体骨移植、肌皮瓣、血管重建、假体重建、术后放疗以及伤口延迟愈合。一些重要的风险因素代表了肿瘤的局部侵袭性,这表明保留软组织对于预防感染非常重要。全国性登记数据的管理为分析恶性软组织肿瘤切除术中的感染提供了信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence and risk of infection in malignant soft tissue tumor resection: Data from the nationwide soft tissue tumor registry

Background

Postoperative infection is a devastating complication in limb salvage surgery for malignant soft tissue tumors. The low absolute case numbers of these rare cancers represent a bottleneck for data collection and analysis. The administration of nationwide registry data is a practical option for the accumulation of cases.

Methods

Data on malignant soft tissue tumor resection were extracted from the Bone and Soft Tissue Tumor Registry in Japan. The incidence of postoperative infection and its risk factors were analyzed.

Results

A total of 14,460 cases were included. The incidence of infection was 2.6%. Significant risks for infection were male sex, lower extremity or trunk location, tumor diameter of over 10 cm, trans-compartmental invasion, high grade, autologous bone graft, myocutaneous flap, vascular reconstruction, reconstruction by prosthesis, postoperative radiotherapy, and delayed wound healing.

Conclusions

The incidence was lower than those in the previous studies, perhaps because of less frequent radiotherapy application. Some of the significant risk factors represented local invasiveness of the tumor, suggesting the importance of the preservation of soft tissue for infection prevention. The administration of nationwide registry data was informative for the analysis of infection in malignant soft tissue tumor resection.

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来源期刊
Journal of Orthopaedic Science
Journal of Orthopaedic Science 医学-整形外科
CiteScore
3.00
自引率
0.00%
发文量
290
审稿时长
90 days
期刊介绍: The Journal of Orthopaedic Science is the official peer-reviewed journal of the Japanese Orthopaedic Association. The journal publishes the latest researches and topical debates in all fields of clinical and experimental orthopaedics, including musculoskeletal medicine, sports medicine, locomotive syndrome, trauma, paediatrics, oncology and biomaterials, as well as basic researches.
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