应用免疫组织化学方法研究内耳电化学梯度的维持。

IF 1.9 4区生物学 Q4 CELL BIOLOGY

Journal of Histochemistry & Cytochemistry Pub Date : 2023-09-01 Epub Date: 2023-08-03 DOI:10.1369/00221554231190438

Bradley A Schulte

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引用次数: 0

摘要

《组织化学与细胞化学杂志》随附经典论文的作者（Crouch JJ，Sakaguchi N，Lytle C，Schulte BA。Gerbil内耳中Na-K-Cl-Co转运蛋白（NKCC1）的免疫组织化学定位。组织化学与细胞化学杂志1997；45（6）:773-778）评论了研究中使用的免疫组织化学技术如何提供关键的新信息，这些信息有助于确定耳朵中电化学梯度的产生和维持所涉及的细胞和分子机制，特别是内耳中Na，K，2Cl转运体（NKCC）的存在。（J Histochem Cytochem 71:509-5102023）。

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Reflections on the Applications of Immunohistochemistry to Understanding the Maintenance of Electrochemical Gradients in the Inner Ear.

The author of the accompanying classic paper from the Journal of Histochemistry and Cytochemistry (Crouch JJ, Sakaguchi N, Lytle C, Schulte BA. Immunohistochemical localization of the Na-K-Cl Co-transporter (NKCC1) in the Gerbil Inner Ear. Journal of Histochemistry & Cytochemistry 1997;45(6):773-778) comments on how the immunohistochemical techniques used in the study provided critical new information that helped define the cellular and molecular mechanisms involved in the generation and maintenance of electrochemical gradients in the ear, particularly the presence of the Na,K,2Cl symporter (NKCC) in the inner ear. (J Histochem Cytochem 71: 509-510, 2023).

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来源期刊

Journal of Histochemistry & Cytochemistry 生物-细胞生物学

CiteScore

6.00

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Journal of Histochemistry & Cytochemistry (JHC) has been a pre-eminent cell biology journal for over 50 years. Published monthly, JHC offers primary research articles, timely reviews, editorials, and perspectives on the structure and function of cells, tissues, and organs, as well as mechanisms of development, differentiation, and disease. JHC also publishes new developments in microscopy and imaging, especially where imaging techniques complement current genetic, molecular and biochemical investigations of cell and tissue function. JHC offers generous space for articles and recognizing the value of images that reveal molecular, cellular and tissue organization, offers free color to all authors.