玛丽-里昂与 X 失活研究的诞生。

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2023-09-13 DOI:10.1038/s41576-023-00655-0

Marnie E. Blewitt

引用次数: 0

摘要

玛妮-布莱维特重点介绍了玛丽-里昂（Mary Lyon）在 1961 年发表的一篇具有远见卓识的论文，她在这篇论文中提出，雌性哺乳动物的剂量补偿涉及 X 失活，并认识到这对 X 连锁疾病中性别特异性表型的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mary Lyon and the birth of X-inactivation research

Marnie Blewitt highlights the visionary 1961 paper by Mary Lyon in which she proposed that dosage compensation in female mammals involves X-inactivation and recognized its implications for sex-specific phenotypes in X-linked disorders.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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