Acquired Anophthalmic Socket: Clinical Course and Treatment Options.

Congenital anophthalmia may be caused by an early pathology in the gestational development of the optic vesicle. It can be further divided into “true” anophthalmia and “clinical” anophthalmia.1 “True” anophthalmia is a rare condition, defined as the complete absence of ocular tissue within the orbit and is typically associated with other severe intracranial disorders. The term “clinical” anophthalmia is more accurate for describing most situations with no clinically apparent eye (Figure 1). Although there may be no visible globe, there is, however, almost always some rudimentary ocular structure that can be observed on orbital imaging.2 The smaller the eye remnant, the more severely retarded the growth of the eyelids and orbit.1