早期自发孪晶记录的时间推移。

IF 1 4区医学 Q4 GENETICS & HEREDITY

Twin Research and Human Genetics Pub Date : 2023-06-01 Epub Date: 2023-09-01 DOI:10.1017/thg.2023.24

Roberto Matorras, Alberto Vendrell, Marcos Ferrando, Zaloa Larreategui

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引用次数: 0

摘要

单卵双胞胎（MZT）在ART中的发生率是自然受孕的2.5倍。许多ART相关机制可能与MZT有关。回顾性分析导致MZT的时间推移（TL）记录的研究表明，内部细胞团和滋养外胚层的一些形态动力学特征可能是MZT预测因素，但结果存在争议。我们提供了一例MZT的完整TL记录，该病例在分裂成两个细胞的瞬间将自身分裂，其中一个细胞从透明带（ZP）的一个孔中出来。两个产生的胚胎发育正常，并被玻璃化。提示ZP中的孔可能有利于某些细胞的挤出

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Early Spontaneous Twinning Recorded By Time-Lapse.

Monozygotic twins (MZT) are 2.5 times more frequent in ART than in natural conceptions. A number of ART-related mechanisms have been probably linked with MZT. Studies that retrospectively analyze the time-lapse (TL) records resulting in MZT suggest that some morphokinetic traits of the inner cell mass and the trophectoderm could be predictors of MZT, but results are controversial. We present the complete TL record of one case of MZT that split itself at the very moment of the division into two cells, with one of the cells coming out through a hole in the zona pellucida (ZP). Both resulting embryos developed normally, and were vitrified. It is suggested that the hole in the ZP may facilitate the extrusion of some cells of the

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来源期刊

Twin Research and Human Genetics 医学-妇产科学

CiteScore

1.50

自引率

11.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.