复杂血管内主动脉修复术后患者的健康和生活质量:一项前瞻性队列研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Linda Haakseth RN, MSc , Caisa Öster RN , Anders Wanhainen MD , Kevin Mani MD , Eva Jangland RN
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引用次数: 0

摘要

理性复杂的血管内主动脉修复通常涉及多个主要手术,并发症风险高,恢复时间短。这使患者在身体和精神上都面临巨大压力,并可能产生长期影响。关于这些影响以及谁的风险最大,目前知之甚少——有关这方面的信息可以帮助血管护士和其他医疗保健专业人员预测并满足护理需求。目的探讨复杂血管内主动脉修复术对患者健康和生活质量的影响,以及与患者人口统计学和健康特征的关系。设计一项前瞻性队列研究。方法在一年内从一所大学医院连续招募接受选择性复杂血管内主动脉修复的患者(n=25)。术前填写健康残疾(WHODAS 2.0)、生活质量(WHOQoL BREF)和焦虑抑郁症状(HADS)的自我报告问卷,术后1个月和6个月重复。评估了健康和生活质量的前瞻性变化,以及与患者人口统计和术前健康特征的相关性。在进行研究之前获得伦理批准。结果总的来说,患者在一个月时的健康残疾(WHODAS 2.0评分中位数31.5,范围1.1-63.0)明显大于术前(中位数13.6,范围0.0-41.3)(n=22,p=.017);大多数人在6个月时已经康复(中位数11.4,范围3.3–58.7)(n=18,p=.042)。在生活质量以及焦虑和抑郁症状方面没有观察到显著影响(p>;.05)。然而,参与者表现出异质性,某些人在6月时没有康复(n=8)。与更差的六个月结果相关的因素是女性、年龄<;70岁,术后并发症,有焦虑或抑郁病史。结论复杂的主动脉腔内修复术对患者健康和生活质量的长期负面影响有限。然而,一些患者在术后6个月仍未康复,这可以用个体特征来解释。为了改善康复结果,血管护士和其他医疗保健专业人员应了解可能的康复轨迹和与康复受损相关的因素,并利用它们来预测和满足患者的个人护理需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patients’ health and quality of life after complex endovascular aortic repair: A prospective cohort study

Rationale

Complex endovascular aortic repair often involves multiple major procedures over time with a high risk of complications and little time for recovery. This exposes patients to great stress, both physically and mentally, with potentially long-lasting effects. There is limited knowledge about these effects and who is most at risk – information on this could help vascular nurses and other healthcare professionals anticipate and meet care needs.

Aim

To investigate the health and quality of life effects of complex endovascular aortic repair, in relation to patients’ demographic and health characteristics.

Design

A prospective cohort study.

Methods

Patients undergoing elective complex endovascular aortic repair were consecutively recruited from one university hospital during one year (n=25). Self-report questionnaires on health disability (WHODAS 2.0), quality of life (WHOQoL-BREF) and symptoms of anxiety and depression (HADS) were filled out preoperatively and repeated one and six months postoperatively. Prospective changes in health and quality of life, and associations with patient demographics and preoperative health characteristics, were assessed. Ethical approval was obtained prior to study performance.

Results

Overall, patients had significantly greater health disability at one month (WHODAS 2.0 score median 31.5, range 1.1–63.0) than preoperatively (median 13.6, range 0.0–41.3) (n=22, p=.017); the majority had recovered at six months (median 11.4, range 3.3–58.7) (n=18, p=.042). No significant effects were seen in quality of life and symptoms of anxiety and depression (p>.05). However, the participants showed heterogeneity, with certain individuals not recovered at six months (n=8). Factors associated with worse six-month outcomes were being female, age < 70 years, postoperative complications, and history of anxiety or depression.

Conclusions

Complex endovascular aortic repair have limited long-term negative effects on patients’ health and quality of life. However, some patients are not recovered at six months postoperatively, which could be explained by individual characteristics. To improve recovery outcomes, vascular nurses and other health care professionals should be aware of the possible recovery trajectories and factors associated with impaired recovery, and use them to anticipate and meet the patients’ individual care needs.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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