Xiaodan Li, Tianzhu Liu, Jun Chen, Jiahui Tang, Wanchun Zhang, Juan Du, Lina Li, Lesheng Huang
{"title":"月经周期期间子宫体素内非相干运动和弥散加权成像的视野优化和约束无畸变单镜头研究:一项前瞻性研究。","authors":"Xiaodan Li, Tianzhu Liu, Jun Chen, Jiahui Tang, Wanchun Zhang, Juan Du, Lina Li, Lesheng Huang","doi":"10.4274/dir.2023.232188","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the variability of the uterus during the menses phase (MP), follicular phase (FP), and luteal phase (LP) of the menstrual cycle using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI).</p><p><strong>Methods: </strong>This prospective study was conducted at the Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2022 and January 2023. Women of childbearing age (18-45 years) with appropriate progesterone levels were included in this study. Conventional magnetic resonance imaging and IVIM-DWI scans were performed during the MP, FP, and LP. The differences in IVIM-DWI-derived parameters between these phases were then compared, and the overlap was quantitatively described.</p><p><strong>Results: </strong>The apparent diffusion coefficient (ADC) and pure molecular diffusion coefficient (<i>D</i>) values from the endometrium, uterine junctional zone (UJZ), and myometrium indicated statistical differences between the MP and FP and the MP and LP (ADC: endometrium, both <i>P</i> < 0.001; UJZ, <i>P</i> = 0.008 and <i>P</i> < 0.001, respectively; myometrium, <i>P</i> = 0.033 and <i>P</i> = 0.006, respectively; D: endometrium, both <i>P</i> < 0.001; UJZ, <i>P</i> = 0.008 and <i>P</i> = 0.006, respectively; myometrium, <i>P</i> = 0.041 and <i>P</i> = 0.045, respectively). The perfusion-related diffusion coefficient (<i>D*</i>) values from the myometrium indicated statistical differences between the FP and MP and the FP and LP (<i>D*</i>: myometrium, <i>P</i> = 0.049 and <i>P</i> = 0.009, respectively). The overlapping endometrium ratios between the MP and FP or LP were lower than 50% in the ADC and <i>D</i> values (ADC: overlapping of MP and FP: 33.33%, overlapping of MP and LP: 23.33%; <i>D</i>: overlapping of MP and FP: 40.00%, overlapping of MP and LP: 43.33%).</p><p><strong>Conclusion: </strong>The ADC and IVIM-derived parameters indicated differences in the uterus in diverse phases of the menstrual cycle, especially in the endometrium in relation to ADC and <i>D</i> values.</p>","PeriodicalId":11341,"journal":{"name":"Diagnostic and interventional radiology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679544/pdf/","citationCount":"0","resultStr":"{\"title\":\"Field-of-view optimized and constrained undistorted single-shot study of intravoxel incoherent motion and diffusion-weighted imaging of the uterus during the menstrual cycle: a prospective study.\",\"authors\":\"Xiaodan Li, Tianzhu Liu, Jun Chen, Jiahui Tang, Wanchun Zhang, Juan Du, Lina Li, Lesheng Huang\",\"doi\":\"10.4274/dir.2023.232188\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aimed to compare the variability of the uterus during the menses phase (MP), follicular phase (FP), and luteal phase (LP) of the menstrual cycle using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI).</p><p><strong>Methods: </strong>This prospective study was conducted at the Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2022 and January 2023. Women of childbearing age (18-45 years) with appropriate progesterone levels were included in this study. Conventional magnetic resonance imaging and IVIM-DWI scans were performed during the MP, FP, and LP. The differences in IVIM-DWI-derived parameters between these phases were then compared, and the overlap was quantitatively described.</p><p><strong>Results: </strong>The apparent diffusion coefficient (ADC) and pure molecular diffusion coefficient (<i>D</i>) values from the endometrium, uterine junctional zone (UJZ), and myometrium indicated statistical differences between the MP and FP and the MP and LP (ADC: endometrium, both <i>P</i> < 0.001; UJZ, <i>P</i> = 0.008 and <i>P</i> < 0.001, respectively; myometrium, <i>P</i> = 0.033 and <i>P</i> = 0.006, respectively; D: endometrium, both <i>P</i> < 0.001; UJZ, <i>P</i> = 0.008 and <i>P</i> = 0.006, respectively; myometrium, <i>P</i> = 0.041 and <i>P</i> = 0.045, respectively). The perfusion-related diffusion coefficient (<i>D*</i>) values from the myometrium indicated statistical differences between the FP and MP and the FP and LP (<i>D*</i>: myometrium, <i>P</i> = 0.049 and <i>P</i> = 0.009, respectively). The overlapping endometrium ratios between the MP and FP or LP were lower than 50% in the ADC and <i>D</i> values (ADC: overlapping of MP and FP: 33.33%, overlapping of MP and LP: 23.33%; <i>D</i>: overlapping of MP and FP: 40.00%, overlapping of MP and LP: 43.33%).</p><p><strong>Conclusion: </strong>The ADC and IVIM-derived parameters indicated differences in the uterus in diverse phases of the menstrual cycle, especially in the endometrium in relation to ADC and <i>D</i> values.</p>\",\"PeriodicalId\":11341,\"journal\":{\"name\":\"Diagnostic and interventional radiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-09-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679544/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic and interventional radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4274/dir.2023.232188\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/8/9 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic and interventional radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4274/dir.2023.232188","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/8/9 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究旨在利用体素内非相干运动弥散加权成像(IVIM-DWI)比较月经周期月经期(MP)、卵泡期(FP)和黄体期(LP)子宫的变异性。方法:本前瞻性研究于2022年1月至2023年1月在广东省中医院进行。孕酮水平适宜的育龄妇女(18-45岁)被纳入本研究。在MP, FP和LP期间进行常规磁共振成像和IVIM-DWI扫描。然后比较这些相之间ivim - dwi衍生参数的差异,并定量描述重叠。结果:子宫内膜、子宫结带(UJZ)、子宫肌层的表观扩散系数(ADC)、纯分子扩散系数(D)值与MP、FP、MP、LP (ADC:子宫内膜)比较均有统计学差异,P < 0.001;UJZ, P = 0.008, P < 0.001;肌层,P = 0.033, P = 0.006;D:子宫内膜,均P < 0.001;UJZ, P = 0.008, P = 0.006;肌层,P = 0.041和P = 0.045)。肌层灌注相关扩散系数(D*)值显示FP与MP、FP与LP之间存在统计学差异(D*:肌层,P = 0.049、P = 0.009)。在ADC和D值上,MP与FP或LP的子宫内膜重叠比例均低于50% (ADC: MP与FP重叠:33.33%,MP与LP重叠:23.33%;D: MP与FP重叠:40.00%,MP与LP重叠:43.33%)。结论:ADC和ivim衍生参数显示月经周期不同阶段子宫的差异,特别是与ADC和D值相关的子宫内膜。
Field-of-view optimized and constrained undistorted single-shot study of intravoxel incoherent motion and diffusion-weighted imaging of the uterus during the menstrual cycle: a prospective study.
Purpose: This study aimed to compare the variability of the uterus during the menses phase (MP), follicular phase (FP), and luteal phase (LP) of the menstrual cycle using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI).
Methods: This prospective study was conducted at the Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2022 and January 2023. Women of childbearing age (18-45 years) with appropriate progesterone levels were included in this study. Conventional magnetic resonance imaging and IVIM-DWI scans were performed during the MP, FP, and LP. The differences in IVIM-DWI-derived parameters between these phases were then compared, and the overlap was quantitatively described.
Results: The apparent diffusion coefficient (ADC) and pure molecular diffusion coefficient (D) values from the endometrium, uterine junctional zone (UJZ), and myometrium indicated statistical differences between the MP and FP and the MP and LP (ADC: endometrium, both P < 0.001; UJZ, P = 0.008 and P < 0.001, respectively; myometrium, P = 0.033 and P = 0.006, respectively; D: endometrium, both P < 0.001; UJZ, P = 0.008 and P = 0.006, respectively; myometrium, P = 0.041 and P = 0.045, respectively). The perfusion-related diffusion coefficient (D*) values from the myometrium indicated statistical differences between the FP and MP and the FP and LP (D*: myometrium, P = 0.049 and P = 0.009, respectively). The overlapping endometrium ratios between the MP and FP or LP were lower than 50% in the ADC and D values (ADC: overlapping of MP and FP: 33.33%, overlapping of MP and LP: 23.33%; D: overlapping of MP and FP: 40.00%, overlapping of MP and LP: 43.33%).
Conclusion: The ADC and IVIM-derived parameters indicated differences in the uterus in diverse phases of the menstrual cycle, especially in the endometrium in relation to ADC and D values.
期刊介绍:
Diagnostic and Interventional Radiology (Diagn Interv Radiol) is the open access, online-only official publication of Turkish Society of Radiology. It is published bimonthly and the journal’s publication language is English.
The journal is a medium for original articles, reviews, pictorial essays, technical notes related to all fields of diagnostic and interventional radiology.