终生疟疾风险的性别相关差异。

3区医学 Q2 Medicine

Current topics in microbiology and immunology Pub Date : 2023-01-01 DOI:10.1007/978-3-031-35139-6_7

Jessica Briggs, Margaret Murray, Jason Nideffer, Prasanna Jagannathan

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引用次数: 0

摘要

尽管全世界的疟疾负担很高，但关于妊娠期以外疟疾性别差异的研究却少得惊人。更彻底地了解疟疾的两性异形，以及这些基于性别的差异背后的原因，可以阐明驱动疟疾发病机制的潜在机制，并有可能为疟疾控制工作提供信息，包括新疫苗。这篇综述总结了我们目前对疟疾流行病学在整个生命周期中基于性别的差异的理解，驱动这些差异的潜在基于性别或性别的机制，以及需要解决的知识差距。

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Sex-Linked Differences in Malaria Risk Across the Lifespan.

Despite the high burden of malaria worldwide, there is surprisingly scarce research on sex-based differences in malaria outside of pregnancy. A more thorough understanding of sexual dimorphism in malaria, and what underlies these sex-based differences, could elucidate the underlying mechanisms driving malaria pathogenesis and has the potential to inform malaria control efforts, including new vaccines. This review summarizes our current understanding of sex-based differences in the epidemiology of malaria across the lifespan, potential sex- or gender-based mechanisms driving these differences, and the knowledge gaps that need to be addressed.

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来源期刊

Current topics in microbiology and immunology 医学-免疫学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The review series Current Topics in Microbiology and Immunology provides a synthesis of the latest research findings in the areas of molecular immunology, bacteriology and virology. Each timely volume contains a wealth of information on the featured subject. This review series is designed to provide access to up-to-date, often previously unpublished information.