谷草转氨酶与丙氨酸转氨酶(De Ritis)比值对嵌套腹股沟疝患者肠坏死的预测价值。

IF 0.5 4区医学 Q4 SURGERY

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI:10.24875/CIRU.22000273

Umit Turan, Ahmet Baris-Dirim

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引用次数: 0

摘要

目的:嵌顿性腹股沟疝(IIH)致肠段坏死的早期诊断对降低发病率和死亡率至关重要。本研究的目的是研究德炎比(DRR)，也称为天冬氨酸转氨酶与丙氨酸转氨酶的比值，作为肠坏死的生物标志物的有效性。方法:本回顾性研究纳入132例因IIH接受急诊手术的患者。患者分为两组:接受肠坏死切除术的患者(1组)和未接受肠坏死切除术的患者(2组)。记录患者的人口统计学和临床资料。根据实验室检测结果，计算DRR、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、淋巴细胞与单核细胞比值(LMR)和淋巴细胞与crp比值(LCR)。结果:两组患者的发病率、死亡率及住院时间比较，差异有统计学意义(p < 0.0001)。同一组的DRR、NLR、PLR、LMR、LCR值差异均有统计学意义(p < 0.05)。结论:DRR可作为IIH患者肠坏死早期诊断的生物标志物。

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Predictivity of aspartate aminotransferase to alanine aminotransferase (De Ritis) ratio for detecting bowel necrosis in incarcerated inguinal hernia patients.

Purpose: Early diagnosis of necrotic bowel segment resulting from incarcerated inguinal hernia (IIH) is crucial for reducing morbidity and mortality. The aim of this study was to investigate the efficacy of the De Ritis ratio (DRR), also known as the ratio of aspartate aminotransferase to alanine aminotransferase, as a biomarker for intestinal necrosis.

Methods: This retrospective study included 132 patients who underwent emergency surgery for IIH. Patients were divided into two groups: those who underwent bowel resection for necrosis (Group 1) and those who did not (Group 2). Patients' demographic and clinical data were recorded. Using laboratory test results, DRR, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and lymphocyte-to-CRP ratio (LCR) were calculated.

Results: The morbidity and mortality rates and the length of stay for Group 1 were statistically significantly different (p < 0.0001). The DRR, NLR, PLR, LMR, and LCR values of the same group were also significantly different (p < 0.05).

Conclusion: DRR can be used as a biomarker for early diagnosis of bowel necrosis in patients with IIH.

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来源期刊

Cirugia Y Cirujanos 医学-外科

CiteScore

0.90

自引率

20.00%

发文量

207

审稿时长

6-12 weeks

期刊介绍： Cirugía y Cirujanoses exponente del desarrollo académico, científico, médico, quirúrgico y tecnológico en materia de salud en México y en el ámbito internacional. Es una revista bimestral, open access, revisada por pares, que publica en español y en inglés (traducido sin coste para los autores) artículos científicos originales, casos clínicos, artículos de revisión de interés general y cartas al editor. Los artículos se seleccionan y publican siguiendo un riguroso análisis, de acuerdo con los estándares internacionalmente aceptados. Sus espacios están abiertos a los académicos, así como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos.