2021年11月12日星期五，苏格兰儿科学会圣安德鲁日儿科研讨会。

IF 1.4 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Scottish Medical Journal Pub Date : 2023-08-01 DOI:10.1177/00369330231187717

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Scottish Paediatric Society St Andrew's Day Paediatric Symposium Friday 12th November 2021.

Background: Children with Down syndrome (DS) are at increased risk of coeliac disease (CD). Current screening practice in DS includes tissue transglutaminase IgA (TGA-IgA) serology. There is no standard UK guidance on the frequency of serology testing or inclusion of HLA-typing for CD predisposing antigens, DQ2 and DQ8. HLA testing can be performed before gluten exposure and to coincide with other routine investigations. A negative DQ2/DQ8 type means patients do not require further coeliac screening. A positive DQ2/DQ8 type allows risk strati ﬁ cation of patients. We explored the cost-effectiveness and family acceptance of a screening strategy that involved both serology and HLA-typing of children with DS. Methods

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来源期刊

Scottish Medical Journal 医学-医学：内科

CiteScore

4.80

自引率

3.70%

发文量

审稿时长

>12 weeks

期刊介绍： A unique international information source for the latest news and issues concerning the Scottish medical community. Contributions are drawn from Scotland and its medical institutions, through an array of international authors. In addition to original papers, Scottish Medical Journal publishes commissioned educational review articles, case reports, historical articles, and sponsoring society abstracts.This journal is a member of the Committee on Publications Ethics (COPE).