血管性痴呆的影像学、遗传学和病理学特征。

IF 2.1 4区医学 Q3 CLINICAL NEUROLOGY

European Neurology Pub Date : 2023-01-01 DOI:10.1159/000531088

Xiaoni Yang, Chao Chen, Aishuai Wang, Changsheng Li, Guangqing Cheng

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引用次数: 0

摘要

背景:在过去的几十年里，通过诊断概念的成熟和脑成像尤其是MRI的进步，血管性痴呆(VD)的检测取得了显著的进展。本文综述了VD的影像学、遗传学和病理特征。摘要:对于VD的诊断和治疗是一个挑战，特别是对于脑血管事件和认知功能障碍之间没有明显的时间关系的患者。卒中后认知功能障碍患者的病因分类仍很复杂。在这篇综述中，我们总结了VD的临床、影像学、遗传学和病理学特征。我们希望提供一个框架，将诊断标准转化为日常实践，解决治疗问题，并强调一些未来的观点。

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Imaging, Genetic, and Pathological Features of Vascular Dementia.

Background: Over the past decades, marked progress has been made in detecting vascular dementia (VD) both through maturation of diagnostic concepts and advances in brain imaging, especially MRI. We summarized the imaging, genetic, and pathological features of VD in this review.

Summary: It is a challenge for the diagnosis and treatment of VD, particularly in patients where there is no evident temporal relation between cerebrovascular events and cognitive dysfunction. In patients with cognitive dysfunction with poststroke onset, the etiological classification is still complicated.

Key messages: In this review, we summarized the clinical, imaging, and genetic as well as pathological features of VD. We hope to offer a framework to translate diagnostic criteria to daily practice, address treatment, and highlight some future perspectives.

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来源期刊

European Neurology 医学-临床神经学

CiteScore

4.40

自引率

4.20%

发文量

审稿时长

4-8 weeks

期刊介绍： ''European Neurology'' publishes original papers, reviews and letters to the editor. Papers presented in this journal cover clinical aspects of diseases of the nervous system and muscles, as well as their neuropathological, biochemical, and electrophysiological basis. New diagnostic probes, pharmacological and surgical treatments are evaluated from clinical evidence and basic investigative studies. The journal also features original works and reviews on the history of neurology.