韩国果蝇神经遗传学研究的历史。

IF 1.8 4区 医学 Q3 GENETICS & HEREDITY
Greg S B Suh, Kweon Yu, Young-Joon Kim, Yangkyun Oh, Joong-Jean Park
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引用次数: 1

摘要

使用果蝇模型的神经遗传学研究在世界范围内得到了极大的扩展。同样,韩国科学家利用果蝇遗传工具的优势来理解各种神经生物学过程。在本期特刊中,我们将概述韩国果蝇神经遗传学研究的历史,这些研究导致了重大发现和显著影响。我们将描述果蝇系统如何在20世纪90年代首次被引入以提升神经发育研究。建立与果蝇相关的资源是一项关键的冒险,它导致了超过10万个突变系的产生,并与韩国果蝇研究中心(KDRC)启动了K-Gut计划。这些资源支持了人类疾病建模和理解调节动物行为和生理的基因和神经回路的先驱研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
History of Drosophila neurogenetic research in South Korea.

Neurogenetic research using the Drosophila model has immensely expanded around the world. Likewise, scientists in South Korea have leveraged the advantages of Drosophila genetic tools to understand various neurobiological processes. In this special issue, we will overview the history of Drosophila neurogenetic research in South Korea that led to significant discoveries and notably implications. We will describe how Drosophila system was first introduced to elevate neural developmental studies in 1990s. Establishing Drosophila-related resources has been a key venture, which led to the generation of over 100,000 mutant lines and the launch of the K-Gut initiative with Korea Drosophila Research Center (KDRC). These resources have supported the pioneer studies in modeling human disease and understanding genes and neural circuits that regulate animal behavior and physiology.

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来源期刊
Journal of neurogenetics
Journal of neurogenetics 医学-神经科学
CiteScore
4.40
自引率
0.00%
发文量
13
审稿时长
>12 weeks
期刊介绍: The Journal is appropriate for papers on behavioral, biochemical, or cellular aspects of neural function, plasticity, aging or disease. In addition to analyses in the traditional genetic-model organisms, C. elegans, Drosophila, mouse and the zebrafish, the Journal encourages submission of neurogenetic investigations performed in organisms not easily amenable to experimental genetics. Such investigations might, for instance, describe behavioral differences deriving from genetic variation within a species, or report human disease studies that provide exceptional insights into biological mechanisms
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