平滑肌瘤中的黄粒细胞改变:一例极为罕见的变异/变性改变的首次报告。

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY
Journal of Mid-life Health Pub Date : 2023-01-01 Epub Date: 2023-07-07 DOI:10.4103/jmh.jmh_158_22
Mukta Pujani, Kanika Singh, Varsha Chauhan, Aparna Khandelwal, Raina Chawla, Rashmi Ahuja
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引用次数: 0

摘要

黄粒细胞性炎症是一种特殊形式的慢性炎症,其特征是实质破坏、增殖性纤维化和典型的泡沫状组织细胞与含铁血黄素的巨噬细胞和异物巨细胞混合浸润。子宫肌黄色瘤病是指子宫肌层结节性或弥漫性组织细胞增生,据报道与妊娠相关的手术有关。此外,在平滑肌瘤区域观察到组织细胞计数是邻近正常子宫肌层的2-3倍。载脂巨噬细胞聚集的第一个证据是子宫平滑肌瘤的黄色变性。我们报告一例47岁女性平滑肌瘤黄色肉芽肿性改变,表现为异常子宫出血。据我们所知,这是第一例平滑肌瘤中黄色肉芽肿性变异/退行性改变的报告。该病例强调了一种新的平滑肌瘤变体,妇科医生和病理学家都应该意识到这一点,因为它可能会在临床和病理上对诊断提出挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Xanthogranulomatous Change in a Leiomyoma: First Report of an Extremely Rare Variant/Degenerative Change.

Xanthogranulomatous Change in a Leiomyoma: First Report of an Extremely Rare Variant/Degenerative Change.

Xanthogranulomatous Change in a Leiomyoma: First Report of an Extremely Rare Variant/Degenerative Change.

Xanthogranulomatous inflammation, a specific form of chronic inflammation, is marked by parenchymal destruction, proliferative fibrosis, and infiltration of typical foamy histiocytes admixed with hemosiderin-laden macrophages and foreign-body giant cells. Myometrial xanthomatosis, a term designated for nodular or diffuse histiocytic hyperplasia of the myometrium, has been reported in association with pregnancy-related procedures. Moreover, a 2-3-fold increase in histiocytic counts has been observed in leiomyomatous areas than in adjacent normal myometrium. The first evidence of collections of lipid-laden macrophages was documented in the form of yellowish degeneration of uterine leiomyomas. We report a case of xanthogranulomatous change in a leiomyoma in a 47-year-old female who presented with abnormal uterine bleeding. To the best of our knowledge, this is the first report of xanthogranulomatous variant/degenerative change in a leiomyoma. This case highlights a new variant of leiomyoma which both gynecologists and pathologists should be aware of as it may pose a diagnostic challenge both clinically as well as pathologically.

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来源期刊
Journal of Mid-life Health
Journal of Mid-life Health Social Sciences-Health (social science)
CiteScore
1.70
自引率
9.10%
发文量
39
审稿时长
43 weeks
期刊介绍: Journal of mid-life health is the official journal of the Indian Menopause society published Quarterly in January, April, July and October. It is peer reviewed, scientific journal of mid-life health and its problems. It includes all aspects of mid-life health, preventive as well as curative. The journal publishes on subjects such as gynecology, neurology, geriatrics, psychiatry, endocrinology, urology, andrology, psychology, healthy ageing, cardiovascular health, bone health, quality of life etc. as relevant of men and women in their midlife. The Journal provides a visible platform to the researchers as well as clinicians to publish their experiences in this area thereby helping in the promotion of mid-life health leading to healthy ageing, growing need due to increasing life expectancy. The Editorial team has maintained high standards and published original research papers, case reports and review articles from the best of the best contributors both national & international, consistently so that now, it has become a great tool in the hands of menopause practitioners.
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