声音诱导的镇痛不能总是在成年小鼠中观察到。

IF 2.8 3区医学 Q2 NEUROSCIENCES

Molecular Pain Pub Date : 2023-01-01 DOI:10.1177/17448069231197158

Qi-Yu Chen, Jinjin Wan, Mianxian Wang, Shanshan Hong, Min Zhuo

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引用次数: 0

摘要

音乐作为一种辅助治疗人类疼痛的药物似乎很有前景，但其机制仍有待阐明。在啮齿类动物慢性疼痛模型中，很少有研究报道音乐的镇痛作用。最近，周等人指出，声音的镇痛作用取决于小鼠相对于环境噪声的低信噪比（5dB）。然而，尽管采用了多种行为分析方法，我们还是无法将这些发现扩展到听5dB SNR的慢性疼痛小鼠模型中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Sound-induced analgesia cannot always be observed in adult mice.

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Sound-induced analgesia cannot always be observed in adult mice.

Music seems promising as an adjuvant pain treatment in humans, while its mechanism remains to be illustrated. In rodent models of chronic pain, few studies reported the analgesic effect of music. Recently, Zhou et al. stated that the analgesic effects of sound depended on a low (5 dB) signal-to-noise ratio (SNR) relative to ambient noise in mice. However, despite employing multiple behavioral analysis approaches, we were unable to extend these findings to a mice model of chronic pain listening to the 5 dB SNR.

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来源期刊

Molecular Pain 医学-神经科学

CiteScore

5.60

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Molecular Pain is a peer-reviewed, open access journal that considers manuscripts in pain research at the cellular, subcellular and molecular levels. Molecular Pain provides a forum for molecular pain scientists to communicate their research findings in a targeted manner to others in this important and growing field.