精神分裂症患者10年心血管疾病风险与临床特征的关系

IF 1 4区医学 Q4 CLINICAL NEUROLOGY

Noropsikiyatri Arsivi-Archives of Neuropsychiatry Pub Date : 2023-01-01 DOI:10.29399/npa.28292

Yaşar Kapıcı, Bulut Güc, Atilla Tekin, Sabri Abuş

{"title":"精神分裂症患者10年心血管疾病风险与临床特征的关系","authors":"Yaşar Kapıcı, Bulut Güc, Atilla Tekin, Sabri Abuş","doi":"10.29399/npa.28292","DOIUrl":null,"url":null,"abstract":"Introduction: Cardiovascular diseases (CVD) are the one of the most important causes of mortality in patients with schizophrenia. This study aimed to investigate ten-year CVD risk and its relationship with clinical features in patients with schizophrenia.Methods: The sample of the study consisted of 208 patients with a diagnosis of schizophrenia. The Positive and Negative Syndrome Scale (PANSS) was administered to each patient to assess symptom severity of schizophrenia. The 10-year CVD risk of the participants was calculated with the QRISK*3 model.Results: 10-year CVD risk of the patients was found to be 7.4%. The mean healthy heart age (QAGE) of the patients was 53.1. Duration of disease, body mass index (BMI), and negative symptoms severity was positively correlated with 10-year CVD risk in patients with schizophrenia (r=0.57, r=0.37, and r=0.49, respectively). Duration of disease, BMI, and severity of negative symptoms predicted a 10-year CVD risk in patients with schizophrenia (t=4.349 and p<0.001; t=2.108 and p=0.037; t=2.836 and p=0.006 respectively).Conclusion: The findings of this study have shown that duration of disease, negative symptoms, and BMI may be important risk factors for increased CVD risk in patients with schizophrenia.","PeriodicalId":51142,"journal":{"name":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461760/pdf/archneuro-60-231.pdf","citationCount":"0","resultStr":"{\"title\":\"The Relationship of Ten-Year Cardiovascular Disease Risk and Clinical Features in Patients with Schizophrenia.\",\"authors\":\"Yaşar Kapıcı, Bulut Güc, Atilla Tekin, Sabri Abuş\",\"doi\":\"10.29399/npa.28292\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Cardiovascular diseases (CVD) are the one of the most important causes of mortality in patients with schizophrenia. This study aimed to investigate ten-year CVD risk and its relationship with clinical features in patients with schizophrenia.Methods: The sample of the study consisted of 208 patients with a diagnosis of schizophrenia. The Positive and Negative Syndrome Scale (PANSS) was administered to each patient to assess symptom severity of schizophrenia. The 10-year CVD risk of the participants was calculated with the QRISK*3 model.Results: 10-year CVD risk of the patients was found to be 7.4%. The mean healthy heart age (QAGE) of the patients was 53.1. Duration of disease, body mass index (BMI), and negative symptoms severity was positively correlated with 10-year CVD risk in patients with schizophrenia (r=0.57, r=0.37, and r=0.49, respectively). Duration of disease, BMI, and severity of negative symptoms predicted a 10-year CVD risk in patients with schizophrenia (t=4.349 and p<0.001; t=2.108 and p=0.037; t=2.836 and p=0.006 respectively).Conclusion: The findings of this study have shown that duration of disease, negative symptoms, and BMI may be important risk factors for increased CVD risk in patients with schizophrenia.\",\"PeriodicalId\":51142,\"journal\":{\"name\":\"Noropsikiyatri Arsivi-Archives of Neuropsychiatry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461760/pdf/archneuro-60-231.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Noropsikiyatri Arsivi-Archives of Neuropsychiatry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.29399/npa.28292\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Noropsikiyatri Arsivi-Archives of Neuropsychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29399/npa.28292","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

前言:心血管疾病(CVD)是导致精神分裂症患者死亡的最重要原因之一。本研究旨在探讨精神分裂症患者10年CVD风险及其与临床特征的关系。方法:研究样本包括208例诊断为精神分裂症的患者。采用阳性和阴性症状量表(PANSS)评估患者精神分裂症的症状严重程度。采用QRISK*3模型计算受试者10年心血管疾病风险。结果:患者10年心血管疾病风险为7.4%。患者平均健康心脏年龄(QAGE)为53.1。精神分裂症患者病程、体重指数(BMI)和阴性症状严重程度与10年CVD风险呈正相关(r=0.57、r=0.37和r=0.49)。疾病持续时间、BMI和阴性症状严重程度预测精神分裂症患者10年CVD风险(t=4.349和p)。结论:本研究结果表明，疾病持续时间、阴性症状和BMI可能是精神分裂症患者CVD风险增加的重要危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The Relationship of Ten-Year Cardiovascular Disease Risk and Clinical Features in Patients with Schizophrenia.

Introduction: Cardiovascular diseases (CVD) are the one of the most important causes of mortality in patients with schizophrenia. This study aimed to investigate ten-year CVD risk and its relationship with clinical features in patients with schizophrenia.

Methods: The sample of the study consisted of 208 patients with a diagnosis of schizophrenia. The Positive and Negative Syndrome Scale (PANSS) was administered to each patient to assess symptom severity of schizophrenia. The 10-year CVD risk of the participants was calculated with the QRISK*3 model.

Results: 10-year CVD risk of the patients was found to be 7.4%. The mean healthy heart age (QAGE) of the patients was 53.1. Duration of disease, body mass index (BMI), and negative symptoms severity was positively correlated with 10-year CVD risk in patients with schizophrenia (r=0.57, r=0.37, and r=0.49, respectively). Duration of disease, BMI, and severity of negative symptoms predicted a 10-year CVD risk in patients with schizophrenia (t=4.349 and p<0.001; t=2.108 and p=0.037; t=2.836 and p=0.006 respectively).

Conclusion: The findings of this study have shown that duration of disease, negative symptoms, and BMI may be important risk factors for increased CVD risk in patients with schizophrenia.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Noropsikiyatri Arsivi-Archives of Neuropsychiatry CLINICAL NEUROLOGY-

CiteScore

1.70

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Neuropsychiatry (Arch Neuropsychiatry) is the official journal of the Turkish Neuropsychiatric Society. It is published quarterly, and four editions annually constitute a volume. Archives of Neuropsychiatry is a peer reviewed scientific journal that publishes articles on psychiatry, neurology, and behavioural sciences. Both clinical and basic science contributions are welcomed. Submissions that address topics in the interface of neurology and psychiatry are encouraged. The content covers original research articles, reviews, letters to the editor, and case reports.