在验证后使用Charm II放射受体测定技术筛选孟加拉国禽蛋中的抗菌残留物。

IF 2.5 3区 农林科学 Q2 CHEMISTRY, APPLIED
Darmin Chakma, Md Maruf Billah Prince, Md Hedayetul Islam, E M Tanvir, Md Mahamodun Nabi, Wim Reybroeck, James Jacob Sasanya, M Jahurul Islam, Md Nazrul Islam, Md Shahabe Uddin Talukder, Chironjit Kumar Shaha, M A Mannan, A S M Saifullah
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引用次数: 0

摘要

该研究的目的是在没有昂贵的验证仪器的情况下,使用Charm II无线电受体测定法筛选孟加拉国禽蛋中抗菌素残留的存在。这是基于根据欧盟委员会决议2002/657/EC和欧盟委员会实施法规(EU) 2021/808在验证指南中设定的截止值。用添加了固定浓度强力霉素、红霉素A、磺胺嘧啶和青霉素的强化鸡蛋测定截止值和检测能力(CCβ)。其他验证参数包括适用性、坚固性和稳健性。对201份来自本地有机鸡、鸭和商业农场饲养的蛋鸡(棕蛋和白蛋)的蛋液样品进行了检测,经分析,分别有13%、10%和4.5%的蛋液样品检测出磺胺类、大环内酯类/lincosamides和四环素类阳性。在201份鸡蛋混合物样品中,有11份疑似存在多种药物残留。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening for antimicrobial residues in poultry eggs in Bangladesh using Charm II radio-receptor assay technique following validation.

The aim of the study was to screen for the presence of antimicrobial residues in poultry eggs from Bangladesh using the Charm II radio-receptor assay in the absence of expensive confirmatory instrumentation. This was based on cut-off values as set in the validation guidelines according to Commission Decision 2002/657/EC and Commission Implementing Regulation (EU) 2021/808. Fortified eggs spiked with fixed concentrations of doxycycline, erythromycin A, sulphamethazine, and benzylpenicillin were used to determine the cut-off values and detection capabilities (CCβ). Other validation parameters included were applicability, ruggedness, and robustness. A total of 201 egg mix samples from native organic chicken, duck, and commercial farm-raised laying hens (both brown and white eggs) were tested and after analysis 13%, 10%, and 4.5% of the egg mix samples showed positive signals for sulphonamides, macrolides/lincosamides, and tetracyclines, respectively. Presence of multiple drug residues were also suspected in 11 out of 201 egg mix samples.

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来源期刊
CiteScore
5.30
自引率
10.30%
发文量
37
审稿时长
2.7 months
期刊介绍: Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling. Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment. The scope is initially restricted to: Additives - food colours, artificial sweeteners, and preservatives; Residues – veterinary drug and pesticide residues; Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging. Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet. Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.
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