绝经前妇女糖皮质激素诱导的骨质疏松症:风湿病学家的管理。

IF 5.2 2区医学 Q1 RHEUMATOLOGY

Current opinion in rheumatology Pub Date : 2023-05-01 DOI:10.1097/BOR.0000000000000934

Katherine Chakrabarti, W Joseph McCune

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引用次数: 0

摘要

综述目的:本综述旨在总结与绝经前妇女糖皮质激素所致骨质疏松症治疗相关的文献;风湿病学家经常遇到的一个问题，但缺乏良好的临床实践指南。最近的发现:虽然大多数关于骨质疏松症的相关文献只包括绝经后妇女，但随机对照试验和病例报告的数据表明，双膦酸盐对绝经前患者是一种有效且耐受性良好的治疗方法。治疗绝经前骨质疏松症的其他药物的数据不那么可靠。总结:在年轻女性中使用双膦酸盐可能比最初认为的更安全，并且可能用于治疗风湿病临床中糖皮质激素引起的骨质疏松症。需要进一步的研究来继续了解长期风险。

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Glucocorticoid-induced osteoporosis in premenopausal women: management for the rheumatologist.

Purpose of review: This review seeks to summarize the literature relevant to the treatment of glucocorticoid-induced osteoporosis in premenopausal women; an issue commonly encountered by rheumatologists and yet lacking good clinical practice guidelines.

Recent findings: Although most of the relevant literature on osteoporosis includes postmenopausal women only, data from both randomized controlled trials and case reports suggest bisphosphonates can be an effective and well tolerated treatment for premenopausal patients. Data for other medications to treat premenopausal osteoporosis is less robust.

Summary: The use of bisphosphonates in young women may be safer than initially thought and should likely be used for the treatment of glucocorticoid-induced osteoporosis in rheumatology clinics. Further research is needed to continue to understand long-term risk.

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来源期刊

Current opinion in rheumatology 医学-风湿病学

CiteScore

9.70

自引率

2.00%

发文量

审稿时长

6-12 weeks

期刊介绍： A high impact review journal which boasts an international readership, Current Opinion in Rheumatology offers a broad-based perspective on the most recent and exciting developments within the field of rheumatology. Published bimonthly, each issue features insightful editorials and high quality invited reviews covering two or three key disciplines which include vasculitis syndromes, medical physiology and rheumatic diseases, crystal deposition diseases and rheumatoid arthritis. Each discipline introduces world renowned guest editors to ensure the journal is at the forefront of knowledge development and delivers balanced, expert assessments of advances from the previous year.