{"title":"神经内科患者的血浆置换--黑山单个中心的经验。","authors":"Milovan Roganovic, Jevto Erakovic, Ljiljana Radulovic, Slavisa Perunicic, Dragica Milikic, Balsa Vujovic, Zilha Idrizovic, Sandra Vujovic, Mladen Debeljevic, Sanja Gluscevic","doi":"10.1111/1744-9987.14062","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Plasma exchange (PE) is widely used in many immune-based neurological diseases. Our aim is to analyze characteristics of PE in neurological patients at the Clinical Center of Montenegro.</p><p><strong>Methods: </strong>Our study involved neurological patients treated with PE between January 2020 and April 2022.</p><p><strong>Results: </strong>In total, 246 PEs were performed in 43 patients. We divided patients into 4 groups according to indications. In 8/9 multiple sclerosis (MS) patients a decrease of Expanded Dysability Status Scale at least 0.5 was verified. In 14/20 Guillain Barre syndrome patients reduction of Hughes was observed. Four patients with myasthenia gravis (MG) were treated with PE. The most heterogeneous group (4) consisted of patients in whom the mechanism of disease development is assumed to be immune system dysregulation. Fourteen patients had any adverse event.</p><p><strong>Conclusion: </strong>Our results show that PE is widely used and safe in the treatment of neurological diseases.</p>","PeriodicalId":23021,"journal":{"name":"Therapeutic Apheresis and Dialysis","volume":" ","pages":"125-130"},"PeriodicalIF":1.5000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Plasma exchange in neurology patients-experience from single center in Montenegro.\",\"authors\":\"Milovan Roganovic, Jevto Erakovic, Ljiljana Radulovic, Slavisa Perunicic, Dragica Milikic, Balsa Vujovic, Zilha Idrizovic, Sandra Vujovic, Mladen Debeljevic, Sanja Gluscevic\",\"doi\":\"10.1111/1744-9987.14062\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Plasma exchange (PE) is widely used in many immune-based neurological diseases. Our aim is to analyze characteristics of PE in neurological patients at the Clinical Center of Montenegro.</p><p><strong>Methods: </strong>Our study involved neurological patients treated with PE between January 2020 and April 2022.</p><p><strong>Results: </strong>In total, 246 PEs were performed in 43 patients. We divided patients into 4 groups according to indications. In 8/9 multiple sclerosis (MS) patients a decrease of Expanded Dysability Status Scale at least 0.5 was verified. In 14/20 Guillain Barre syndrome patients reduction of Hughes was observed. Four patients with myasthenia gravis (MG) were treated with PE. The most heterogeneous group (4) consisted of patients in whom the mechanism of disease development is assumed to be immune system dysregulation. Fourteen patients had any adverse event.</p><p><strong>Conclusion: </strong>Our results show that PE is widely used and safe in the treatment of neurological diseases.</p>\",\"PeriodicalId\":23021,\"journal\":{\"name\":\"Therapeutic Apheresis and Dialysis\",\"volume\":\" \",\"pages\":\"125-130\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutic Apheresis and Dialysis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/1744-9987.14062\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/8/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic Apheresis and Dialysis","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/1744-9987.14062","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/8/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
导言：血浆置换（PE）被广泛应用于多种神经系统免疫性疾病。我们的目的是分析黑山临床中心神经科患者接受血浆置换治疗的特点：我们的研究涉及 2020 年 1 月至 2022 年 4 月期间接受 PE 治疗的神经科患者：共有43名患者接受了246次PE治疗。我们根据适应症将患者分为 4 组。在 8/9 例多发性硬化症（MS）患者中，扩展失能状态量表（Expanded Dysability Status Scale）至少下降了 0.5。14/20名格林巴利综合征患者的休斯症状有所减轻。四名重症肌无力（MG）患者接受了 PE 治疗。4名患者的发病机制被认为是免疫系统失调。14名患者出现了不良反应：我们的研究结果表明，PE 在治疗神经系统疾病方面应用广泛且安全。
Plasma exchange in neurology patients-experience from single center in Montenegro.
Introduction: Plasma exchange (PE) is widely used in many immune-based neurological diseases. Our aim is to analyze characteristics of PE in neurological patients at the Clinical Center of Montenegro.
Methods: Our study involved neurological patients treated with PE between January 2020 and April 2022.
Results: In total, 246 PEs were performed in 43 patients. We divided patients into 4 groups according to indications. In 8/9 multiple sclerosis (MS) patients a decrease of Expanded Dysability Status Scale at least 0.5 was verified. In 14/20 Guillain Barre syndrome patients reduction of Hughes was observed. Four patients with myasthenia gravis (MG) were treated with PE. The most heterogeneous group (4) consisted of patients in whom the mechanism of disease development is assumed to be immune system dysregulation. Fourteen patients had any adverse event.
Conclusion: Our results show that PE is widely used and safe in the treatment of neurological diseases.
期刊介绍：
Therapeutic Apheresis and Dialysis is the official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis and the Japanese Society for Dialysis Therapy. The Journal publishes original articles, editorial comments, review articles, case reports, meeting abstracts and Communications information on apheresis and dialysis technologies and treatments.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
