肌注硫酸麻黄碱在肾移植中的应用。

IF 3.1 Q2 PHARMACOLOGY & PHARMACY
Gaurav P Patel, Susan A Smith, Michelle Romej, Billynda McAdoo, Elizabeth A Wilson
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引用次数: 0

摘要

肾移植过程中的低血压是很常见的。在这些手术中通常避免使用血管加压剂,因为担心会减少移植肾的肾灌注。然而,身体其他部位的充分灌注也是必要的,考虑到这些患者通常有潜在的高血压或其他合并症,必须维持适当的平均动脉压(MAP)。麻醉学文献对多种病例类型的肌肉注射麻黄碱进行了研究,认为麻黄碱是一种安全有效的提高MAP的方法。我们提出了一个病例系列的三个病人接受肾移植和谁接受肌肉注射麻黄碱控制低血压。这种药对升高血压效果很好,而且没有明显的副作用。3例患者随访1年以上,随访结束时移植物功能良好。这一系列研究表明,虽然在这一领域还需要进一步的研究,但肌注麻黄碱可能在肾移植手术中治疗持续性低血压方面有一定的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of Intramuscular Ephedrine Sulfate During Kidney Transplantation.

Hypotension during kidney transplantation can be common. Vasopressor use during these procedures is often avoided, with a fear of decreasing renal perfusion in the transplanted kidney. However, adequate perfusion for the rest of the body is also necessary, and given that these patients often have underlying hypertension or other comorbid conditions, an appropriate mean arterial pressure (MAP) has to be maintained. Intramuscular injections of ephedrine have been studied in the anesthesiology literature in a variety of case types, and it is seen as a safe and effective method to boost MAP. We present a case series of three patients who underwent renal transplantation and who received an intramuscular injection of ephedrine for hypotension control. The medication worked well for increasing blood pressures without apparent side effects. All three patients were followed for more than one year, and all patients had good graft function at the end of that time period. This series shows that while further research is necessary in this arena, intramuscular ephedrine may have a place in the management of persistent hypotension in the operating room during kidney transplantation.

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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
14
审稿时长
16 weeks
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