急性肺损伤炎症网络的研究。

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY

International journal of clinical pharmacology and therapeutics Pub Date : 2023-09-01 DOI:10.5414/CP204438

Yaru Li, Yanan Jiang, Hui Zhang, Juan Zhang, Junbing Ma, Zheng Yang, Min Qiu, Jing Wang

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引用次数: 0

摘要

急性肺损伤(ALI)是一种肺部全身性炎症反应综合征，发病率高，病死率为30 - 40%。尽管对肺损伤发病机制的研究非常丰富，也取得了很大的进展，但参与ALI发病的各种细胞、细胞因子和炎症反应途径及其复杂的关系，共同构成了ALI炎症反应的细胞网络和炎症因子网络，值得更多的关注。本研究综述了该网络在ALI发病机制中的形成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Research on acute lung injury inflammatory network.

Acute lung injury (ALI) is a systemic inflammatory response syndrome in the lungs, with a high incidence and fatality rate of 30 - 40%. Despite the abundance of research on the pathogenesis of lung injury and the great progress that has been achieved, the various number of cells, cytokines and inflammatory response pathways involved in the pathogenesis of ALI and their complex relationships - which together constitute the cell network and inflammatory factor network of ALI inflammatory response - demand more attention. This study reviews the formation of this network in the pathogenesis of ALI.

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来源期刊

International journal of clinical pharmacology and therapeutics 医学-药学

CiteScore

1.70

自引率

12.50%

发文量

116

审稿时长

4-8 weeks

期刊介绍： The International Journal of Clinical Pharmacology and Therapeutics appears monthly and publishes manuscripts containing original material with emphasis on the following topics: Clinical trials, Pharmacoepidemiology - Pharmacovigilance, Pharmacodynamics, Drug disposition and Pharmacokinetics, Quality assurance, Pharmacogenetics, Biotechnological drugs such as cytokines and recombinant antibiotics. Case reports on adverse reactions are also of interest.