Saeed Karimi, Homayoun Nikkhah, Amir Mohammadzadeh, Alireza Ramezani, Iman Ansari, Hosein Nouri, Seyed-Hossein Abtahi
{"title":"玻璃体内注射和口罩:COVID-19大流行之前和期间的眼内炎风险","authors":"Saeed Karimi, Homayoun Nikkhah, Amir Mohammadzadeh, Alireza Ramezani, Iman Ansari, Hosein Nouri, Seyed-Hossein Abtahi","doi":"10.18502/jovr.v18i3.13776","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To assess the added risk of acute endophthalmitis after intravitreal injections associated with the widespread use of face masks during the COVID-19 pandemic.</p><p><strong>Methods: </strong>In this retrospective, single-center study, records of patients with acute endophthalmitis following intravitreal bevacizumab (IVB) injections during the pre-COVID era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2013 to October 31<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2019 -and the COVID-19 era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2020 to April 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2021 -were reviewed and compared.</p><p><strong>Results: </strong>A total of 28,085 IVB injections were performed during the pre-COVID era; nine eyes of nine patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.032% (3.2 in 10,000 injections). In the COVID era, 10,717 IVB injections were performed; four eyes of four patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.037% (3.7 in 10,000 injections). The incidences of post-IVB endophthalmitis during these two eras were not statistically significantly different (<i>P</i> = 0.779).</p><p><strong>Conclusion: </strong>Face masking protocols seem unlikely to impose any additional risk of post-IVB endophthalmitis.</p>","PeriodicalId":16586,"journal":{"name":"Journal of Ophthalmic & Vision Research","volume":"18 3","pages":"283-288"},"PeriodicalIF":1.6000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432929/pdf/","citationCount":"1","resultStr":"{\"title\":\"Intravitreal Injections and Face Masks: Endophthalmitis Risk Before and During the COVID-19 Pandemic.\",\"authors\":\"Saeed Karimi, Homayoun Nikkhah, Amir Mohammadzadeh, Alireza Ramezani, Iman Ansari, Hosein Nouri, Seyed-Hossein Abtahi\",\"doi\":\"10.18502/jovr.v18i3.13776\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To assess the added risk of acute endophthalmitis after intravitreal injections associated with the widespread use of face masks during the COVID-19 pandemic.</p><p><strong>Methods: </strong>In this retrospective, single-center study, records of patients with acute endophthalmitis following intravitreal bevacizumab (IVB) injections during the pre-COVID era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2013 to October 31<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2019 -and the COVID-19 era-that is, March 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2020 to April 1<math><msup><mrow></mrow><mtext>st</mtext></msup></math>, 2021 -were reviewed and compared.</p><p><strong>Results: </strong>A total of 28,085 IVB injections were performed during the pre-COVID era; nine eyes of nine patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.032% (3.2 in 10,000 injections). In the COVID era, 10,717 IVB injections were performed; four eyes of four patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.037% (3.7 in 10,000 injections). The incidences of post-IVB endophthalmitis during these two eras were not statistically significantly different (<i>P</i> = 0.779).</p><p><strong>Conclusion: </strong>Face masking protocols seem unlikely to impose any additional risk of post-IVB endophthalmitis.</p>\",\"PeriodicalId\":16586,\"journal\":{\"name\":\"Journal of Ophthalmic & Vision Research\",\"volume\":\"18 3\",\"pages\":\"283-288\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432929/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ophthalmic & Vision Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18502/jovr.v18i3.13776\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmic & Vision Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/jovr.v18i3.13776","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Intravitreal Injections and Face Masks: Endophthalmitis Risk Before and During the COVID-19 Pandemic.
Purpose: To assess the added risk of acute endophthalmitis after intravitreal injections associated with the widespread use of face masks during the COVID-19 pandemic.
Methods: In this retrospective, single-center study, records of patients with acute endophthalmitis following intravitreal bevacizumab (IVB) injections during the pre-COVID era-that is, March 1, 2013 to October 31, 2019 -and the COVID-19 era-that is, March 1, 2020 to April 1, 2021 -were reviewed and compared.
Results: A total of 28,085 IVB injections were performed during the pre-COVID era; nine eyes of nine patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.032% (3.2 in 10,000 injections). In the COVID era, 10,717 IVB injections were performed; four eyes of four patients developed acute post-IVB endophthalmitis in this era, giving an overall incidence of 0.037% (3.7 in 10,000 injections). The incidences of post-IVB endophthalmitis during these two eras were not statistically significantly different (P = 0.779).
Conclusion: Face masking protocols seem unlikely to impose any additional risk of post-IVB endophthalmitis.