Budi Wiweko, Ervan Surya, Vita Silvana, Mila Maidarti, Achmad Kemal Harzif, Gita Pratama, Kanadi Sumapraja, R Muharam, Andon Hestiantoro
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Twelve hours post-injection serum hCG levels and oocyte maturation rate data were retrieved and analyzed accordingly.</p><p><strong>Results: </strong>Twenty-eight subjects were recruited into the study. Higher 12 hours post-injection serum hCG was related to oocyte maturation rate (P=0.046). The cut-off point of 12 hours post-injection serum hCG to predict better oocyte maturation rate was 90.15 mIU/mL (sensitivity 68.2%, specificity 83.3%). Oocyte maturation rate may be predicted using body mass index (BMI) and 12 hours post-injection serum hCG.</p><p><strong>Conclusion: </strong>Higher 12 hours post-injection serum hCG was associated with a higher oocyte maturation rate in IVF subjects.</p>","PeriodicalId":14080,"journal":{"name":"International Journal of Fertility & Sterility","volume":"17 4","pages":"264-267"},"PeriodicalIF":2.3000,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/18/Int-J-Fertil-Steril-17-264.PMC10439995.pdf","citationCount":"0","resultStr":"{\"title\":\"Twelve Hours Post-Injection Serum Human Chorionic Gonadotropin and Body Mass Index Predicts <i>In Vitro</i> Fertilization Oocyte Maturation Rate: A Cross-Sectional Study.\",\"authors\":\"Budi Wiweko, Ervan Surya, Vita Silvana, Mila Maidarti, Achmad Kemal Harzif, Gita Pratama, Kanadi Sumapraja, R Muharam, Andon Hestiantoro\",\"doi\":\"10.22074/ijfs.2023.555467.1315\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong><i>In vitro</i> fertilization (IVF) remains a main treatment for infertility cases. 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Twelve Hours Post-Injection Serum Human Chorionic Gonadotropin and Body Mass Index Predicts In Vitro Fertilization Oocyte Maturation Rate: A Cross-Sectional Study.
Background: In vitro fertilization (IVF) remains a main treatment for infertility cases. Post-injection human chorionic gonadotropin (hCG) level is an essential factor in determining oocyte maturation rate in IVF. This study aimed to determine the relationship between 12 hours post-injection serum hCG level and oocyte maturation rate among IVF participants.
Materials and methods: A cross-sectional study on IVF participants was done at a tertiary hospital in Indonesia from January 2020 to December 2021. Subjects were injected with 250 μg of recombinant-hCG (r-hCG) subcutaneously. Twelve hours post-injection serum hCG levels and oocyte maturation rate data were retrieved and analyzed accordingly.
Results: Twenty-eight subjects were recruited into the study. Higher 12 hours post-injection serum hCG was related to oocyte maturation rate (P=0.046). The cut-off point of 12 hours post-injection serum hCG to predict better oocyte maturation rate was 90.15 mIU/mL (sensitivity 68.2%, specificity 83.3%). Oocyte maturation rate may be predicted using body mass index (BMI) and 12 hours post-injection serum hCG.
Conclusion: Higher 12 hours post-injection serum hCG was associated with a higher oocyte maturation rate in IVF subjects.
期刊介绍：
International Journal of Fertility & Sterility is a quarterly English publication of Royan Institute . The aim of the journal is to disseminate information through publishing the most recent scientific research studies on Fertility and Sterility and other related topics. Int J Fertil Steril has been certified by Ministry of Culture and Islamic Guidance in 2007 and was accredited as a scientific and research journal by HBI (Health and Biomedical Information) Journal Accreditation Commission in 2008. Int J Fertil Steril is an Open Access journal.
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