日常生活奖励回路功能对抑郁症病程的影响

IF 3.4 2区 心理学 Q2 PSYCHIATRY
Vera E. Heininga, Daan A. Ornee, Albertine J. Oldehinkel, Jojanneke A. Bastiaansen
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引用次数: 0

摘要

参与活动会增加积极影响(奖励途径1),从而增强动机(奖励途径2),从而提高未来参与活动的能力(奖励途径3)。这三个奖励回路成分之间的紧密联系被认为是适应性的,在抑郁症中可能会受到干扰。尽管一些生态个体评估(EMA)研究调查了单独的奖励途径与个体抑郁水平之间的横断面关联,但没有一项EMA研究调查个体的奖励回路强度与抑郁症状过程之间的关联。目前的EMA研究评估了46名在二级心理健康服务机构开始接受抑郁症治疗的门诊患者的奖赏循环功能(5x/天,28天),并在7个月的时间内使用抑郁症状自评量表(IDS-SR)进行监测。多水平回归分析结果显示,奖励路径1(b = 0.21,p <; .001),奖励路径2(b = 0.43,p <; .001)和奖励路径3(b = 0.20,p <; .001)。更强的平均奖励循环(即所有奖励路径的人内平均值)与参与者随着时间的推移抑郁症状的改善无关。路径特异性结果显示,奖赏路径1和2可能对抑郁症状过程产生部分相反的影响。总之,我们的研究结果表明,日常生活中的奖励过程最好单独研究,有必要进行进一步的调查,以探索在什么情况下强路径是适应性的或不适应性的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Daily Life Reward Loop Functioning on the Course of Depression

Engagement in activities increases positive affect (Reward Path 1), which subsequently reinforces motivation (Reward Path 2), and hence future engagement in activities (Reward Path 3). Strong connections between these three reward loop components are considered adaptive, and might be disturbed in depression. Although some ecological nomentary assessment (EMA) studies have investigated the cross-sectional association between separate reward paths and individuals’ level of depression, no EMA study has looked into the association between individuals’ reward loop strength and depressive symptom course. The present EMA study assessed reward loop functioning (5x/day, 28 days) of 46 outpatients starting depression treatment at secondary mental health services and monitored with the Inventory of Depressive Symptomatology—Self-Report (IDS-SR) during a 7-month period. Results of multilevel regression analyses showed significant within-person associations for Reward Path 1 (b = 0.21, p < .001), Reward Path 2 (b = 0.43, p < .001), and Reward Path 3 (b = 0.20, p < .001). Stronger average reward loops (i.e., within-person mean of all reward paths) did not relate to participants’ improvement in depressive symptoms over time. Path-specific results revealed that Reward Paths 1 and 2 may have partly opposite effects on depressive symptom course. Together, our findings suggest that reward processes in daily life might be best studied separately and that further investigation is warranted to explore under what circumstances strong paths are adaptive or not.

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来源期刊
Behavior Therapy
Behavior Therapy Multiple-
CiteScore
7.40
自引率
2.70%
发文量
113
审稿时长
121 days
期刊介绍: Behavior Therapy is a quarterly international journal devoted to the application of the behavioral and cognitive sciences to the conceptualization, assessment, and treatment of psychopathology and related clinical problems. It is intended for mental health professionals and students from all related disciplines who wish to remain current in these areas and provides a vehicle for scientist-practitioners and clinical scientists to report the results of their original empirical research. Although the major emphasis is placed upon empirical research, methodological and theoretical papers as well as evaluative reviews of the literature will also be published. Controlled single-case designs and clinical replication series are welcome.
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