[交织的长 COVID 理论解释其病因发病机制]。

Luis Del Carpio-Orantes, Andrés Aguilar-Silva
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引用次数: 0

摘要

这篇社论列举了目前有关长COVID的主要理论,如病毒持续存在理论和与免疫系统失调有关的免疫血栓理论;还讨论了它们之间的相互关系,最终解释了困扰COVID-19幸存者的这种新综合征的病因发病机制和生理病理学;还讨论了病毒持续存在与淀粉样微血栓形成之间的联系,其假设基础是尖峰蛋白导致淀粉样蛋白生成,诱发有机慢性损伤,这将成为 COVID 长期病程的特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Intertwined long COVID theories to explain its etiopathogenesis].

This editorial lists the main current theories on long COVID, such as the theory of viral persistence and the one of immunothrombosis associated with deregulation of the immune system; it is discussed as well their interrelation, which finally explains the etiopathogenesis and physiopathology of this new syndrome that afflicts the survivors of COVID-19; it is also discussed the link between viral persistence with the formation of amyloid microthrombi based on the hypothesis that the spike protein causes amyloidogenesis, inducing organic chronic damage that will characterize long COVID.

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