揭开糖尿病的神秘面纱:类别、遗传学、诊断、治疗和未来展望。

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM
Aftab Alam, Shivang Dhoundiyal, Niyaz Ahmad, G S N Koteswara Rao
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引用次数: 0

摘要

糖尿病是一种全球性流行病,影响着全球数百万人。本综述旨在让读者全面了解糖尿病的分类、疾病特征、遗传结构、诊断和治疗。文中讨论了糖尿病的分类,重点是 1 型和 2 型糖尿病,以及不为人知的 3 型和 4 型糖尿病。探讨了 1 型和 2 型糖尿病发病率的地域差异、年龄差异、性别差异和种族差异。研究疾病特征对疾病管理的影响以及自身免疫在糖尿病中的作用。讨论了糖尿病的遗传结构,包括基因型和表型之间的相互作用,以加深我们对其潜在机制的理解。强调胰岛素注射部位和胰岛素信号通路在糖尿病治疗中的重要性。回顾了糖尿病的诊断技术,以及在更好地区分不同类型方面取得的进展。介绍了治疗和管理方法,包括用于糖尿病管理的药物。最后,还讨论了未来的展望,强调了进一步研究和干预的必要性,以解决糖尿病给全球带来的负担。这篇综述是医疗保健专业人员、研究人员和政策制定者的宝贵资源,为制定这一复杂疾病的预防、诊断和管理的针对性策略提供了真知灼见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unveiling Diabetes: Categories, Genetics, Diagnostics, Treatments, and Future Horizons.

Diabetes mellitus is a global epidemic affecting millions of individuals worldwide. This comprehensive review aims to provide a thorough understanding of the categorization, disease identity, genetic architecture, diagnosis, and treatment of diabetes. The categorization of diabetes is discussed, with a focus on type 1 and type 2 diabetes, as well as the lesser-known types, type 3 and type 4 diabetes. The geographical variation, age, gender, and ethnic differences in the prevalence of type 1 and type 2 diabetes are explored. The impact of disease identity on disease management and the role of autoimmunity in diabetes are examined. The genetic architecture of diabetes, including the interplay between genotype and phenotype, is discussed to enhance our understanding of the underlying mechanisms. The importance of insulin injection sites and the insulin signalling pathway in diabetes management are highlighted. The diagnostic techniques for diabetes are reviewed, along with advancements for improved differentiation between types. Treatment and management approaches, including medications used in diabetes management are presented. Finally, future perspectives are discussed, emphasizing the need for further research and interventions to address the global burden of diabetes. This review serves as a valuable resource for healthcare professionals, researchers, and policymakers, providing insights to develop targeted strategies for the prevention, diagnosis, and management of this complex disease.

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来源期刊
Current diabetes reviews
Current diabetes reviews ENDOCRINOLOGY & METABOLISM-
CiteScore
6.30
自引率
0.00%
发文量
158
期刊介绍: Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.
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