采用抗真菌策略的生物材料对抗口腔感染。

IF 8.1 2区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Critical Reviews in Biotechnology Pub Date : 2024-09-01 Epub Date: 2023-08-16 DOI:10.1080/07388551.2023.2236784
Jontana Allkja, Maryam Roudbary, Anelise Maria Vasconcelos Alves, Lucia Černáková, Célia Fortuna Rodrigues
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引用次数: 0

摘要

口腔真菌感染对人类健康构成威胁,并因治疗时间延长和复杂化而增加了口腔疾病的经济负担。一种具有成本效益的策略是从一开始就努力预防这些感染的发生。为此,具有抗真菌特性的生物材料是克服口腔真菌感染的关键因素。在这篇综述中,我们将介绍不同种类的生物材料以及可用于对其进行功能化的涂层。此外,我们还探讨了除预防外,生物材料作为一种治疗方法的潜力,并将传统和替代性抗真菌化合物(如精油)融入其中,以增强其对真菌病原体的功效。我们旨在强调这些技术的潜力,并提出需要在未来研究中解决的问题。最后,我们打算将生物材料在口腔健康领域应用的关键方面和技术汇总起来,为该领域的研究人员提供一份易于查找的当前最新技术摘要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biomaterials with antifungal strategies to fight oral infections.

Oral fungal infections pose a threat to human health and increase the economic burden of oral diseases by prolonging and complicating treatment. A cost-effective strategy is to try to prevent these infections from happening in the first place. With this purpose, biomaterials with antifungal properties are a crucial element to overcome fungal infections in the oral cavity. In this review, we go through different kinds of biomaterials and coatings that can be used to functionalize them. We also review their potential as a therapeutic approach in addition to prophylaxis, by going through traditional and alternative antifungal compounds, e.g., essential oils, that could be incorporated in them, to enhance their efficacy against fungal pathogens. We aim to highlight the potential of these technologies and propose questions that need to be addressed in prospective research. Finally, we intend to concatenate the key aspects and technologies on the use of biomaterials in oral health, to create an easy to find summary of the current state-of-the-art for researchers in the field.

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来源期刊
Critical Reviews in Biotechnology
Critical Reviews in Biotechnology 工程技术-生物工程与应用微生物
CiteScore
20.80
自引率
1.10%
发文量
71
审稿时长
4.8 months
期刊介绍: Biotechnological techniques, from fermentation to genetic manipulation, have become increasingly relevant to the food and beverage, fuel production, chemical and pharmaceutical, and waste management industries. Consequently, academic as well as industrial institutions need to keep abreast of the concepts, data, and methodologies evolved by continuing research. This journal provides a forum of critical evaluation of recent and current publications and, periodically, for state-of-the-art reports from various geographic areas around the world. Contributing authors are recognized experts in their fields, and each article is reviewed by an objective expert to ensure accuracy and objectivity of the presentation.
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