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Immunomodulatory Strategies for Spinal Cord Injury. 脊髓损伤的免疫调节策略。
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-07-01 DOI: 10.26717/bjstr.2022.45.007202
Jonghyuck Park
{"title":"Immunomodulatory Strategies for Spinal Cord Injury.","authors":"Jonghyuck Park","doi":"10.26717/bjstr.2022.45.007202","DOIUrl":"https://doi.org/10.26717/bjstr.2022.45.007202","url":null,"abstract":"<p><p>Neuroinflammation is a key secondary event after spinal cord injury (SCI) and can increase barriers to regeneration, leading to various neurological disorders. Infiltrated hematogenous innate immune cells into the injured site are considered the main effector cells of the inflammatory responses after SCI. Glucocorticoids were the standard of care for spinal cord trauma for years due to their anti-inflammatory properties yet were also associated with unwanted side effects. While the administration of glucocorticoids is controversial, immunomodulatory strategies that limit inflammatory responses provide the potential therapeutic approaches to promote functional regeneration following SCI. Herein, we will discuss emerging therapeutic strategies to modulate inflammatory responses to enhance nerve recovery after spinal cord trauma.</p>","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10264867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Thoracic Disc Herniation Effectively Treated with Interventional Radiology Computed Tomography- Guided Percutaneous Endoscopic Radiofrequency Annuloplasty Using a Disc-Fx® 介入放射学计算机断层引导下经皮内镜下射频环成形术治疗胸椎间盘突出症1例
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-02-04 DOI: 10.26717/bjstr.2022.41.006636
Takayuki Kobayashi
{"title":"A Case of Thoracic Disc Herniation Effectively Treated with Interventional Radiology Computed Tomography- Guided Percutaneous Endoscopic Radiofrequency Annuloplasty Using a Disc-Fx®","authors":"Takayuki Kobayashi","doi":"10.26717/bjstr.2022.41.006636","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006636","url":null,"abstract":"a for whom Interventional Radiology-Computed Tomography (IVR-CT)-guided Percutaneous Endoscopic Radiofrequency Annuloplasty (PERA) performed for the thoracic disc herniation to reduce the incidence of complications and improve treatment results, leading to a favorable outcome","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75124351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 and Human Immune System Responses COVID-19与人体免疫系统反应
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-02-03 DOI: 10.26717/bjstr.2022.41.006633
Sylvia Smart
{"title":"COVID-19 and Human Immune System Responses","authors":"Sylvia Smart","doi":"10.26717/bjstr.2022.41.006633","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006633","url":null,"abstract":"Sylvia Smart. COVID-19 and Human Immune System Responses. Biomed","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87431644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stress Prevalence in College Students During COVID-19 Pandemics: Evidence from Economics Undergraduates in a Developing Country COVID-19大流行期间大学生的压力流行:来自发展中国家经济学本科生的证据
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-02-02 DOI: 10.26717/bjstr.2022.41.006624
Jorge Trevino
{"title":"Stress Prevalence in College Students During COVID-19 Pandemics: Evidence from Economics Undergraduates in a Developing Country","authors":"Jorge Trevino","doi":"10.26717/bjstr.2022.41.006624","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006624","url":null,"abstract":"","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84395222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pore Characterization of Alumina Short Fiber Using Small Angle X-Ray Scattering Technique 利用小角x射线散射技术表征氧化铝短纤维的孔隙结构
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-02-02 DOI: 10.26717/bjstr.2022.41.006622
H. Yazid
{"title":"Pore Characterization of Alumina Short Fiber Using Small Angle X-Ray Scattering Technique","authors":"H. Yazid","doi":"10.26717/bjstr.2022.41.006622","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006622","url":null,"abstract":"","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91099537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of BI-RADS 3 Audits. BI-RADS 3审计值。
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-02-01 DOI: 10.26717/BJSTR.2022.41.006668
Prithwijit Roychowdhury, Gopal R Vijayaraghavan, John Roubil, Imani M Williams, Efaza Siddiqui, Srinivasan Vedantham
{"title":"Value of BI-RADS 3 Audits.","authors":"Prithwijit Roychowdhury,&nbsp;Gopal R Vijayaraghavan,&nbsp;John Roubil,&nbsp;Imani M Williams,&nbsp;Efaza Siddiqui,&nbsp;Srinivasan Vedantham","doi":"10.26717/BJSTR.2022.41.006668","DOIUrl":"https://doi.org/10.26717/BJSTR.2022.41.006668","url":null,"abstract":"<p><strong>Objectives: </strong>BI-RADS 3 is an established assessment category in which the probability of malignancy is equal to or less than 2%. However, monitoring adherence to imaging criteria can be challenging and there are few established benchmarks for auditing BI-RADS 3 assignments. In this study, we explore some parameters that could serve as useful tools for quality control and clinical practice management.</p><p><strong>Materials and methods: </strong>This retrospective study covered a 4-year period (Jan 2014-Dec 2017) and included all women over 40 years who were recalled from a screening exam and had an initial assignment of BI-RADS 3 (probably benign) category after diagnostic workup. A follow-up period of 2 years following the assignment of BI-RADS 3 was used for quantitative quality control metrics.</p><p><strong>Results: </strong>Among 135,765 screening exams, 13,453 were recalled and 1,037 BI-RADS 3 cases met inclusion criteria. The follow-up rate at 24 months was 86.7%. The upgrade rate was 7.4% (77/1,037) [CI: 5.9-9.2%] and the PPV3 was 33.8% (26/77) [CI: 23.4-45.5%]. The cancer yield was 2.51% (26/1,037) [CI: 1.64-3.65%] and did not differ (p=0. 243) from the 2% probability of malignancy. The initial BI-RADS3 per screening exam and per recall from screening were 0.76% (1,037/135,765) [CI: 0.72-0.81%] and 7.7% (1,037/13,453) [CI: 7.26-8.17%], respectively.</p><p><strong>Conclusion: </strong>Regular audit of BIRADS 3 metrics has the potential to provide additional insights for clinical practice management. Data from varied clinical settings with input from an expert committee could help establish benchmarks for these metrics.</p>","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983005/pdf/nihms-1790042.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10711605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
SNP Genotyping Enhancements: From Traditional PCR to Double Helix Structural Oligonucleotides (STexS) SNP基因分型增强:从传统PCR到双螺旋结构寡核苷酸(STexS)
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-01-26 DOI: 10.26717/bjstr.2022.41.006585
Hyoung Min Park
{"title":"SNP Genotyping Enhancements: From Traditional PCR to Double Helix Structural Oligonucleotides (STexS)","authors":"Hyoung Min Park","doi":"10.26717/bjstr.2022.41.006585","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006585","url":null,"abstract":"","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76250724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumors Originating from Fat Tissue in the Head and Neck Area: A Review of 40 Cases 头颈部脂肪源性肿瘤40例临床分析
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-01-26 DOI: 10.26717/bjstr.2022.41.006589
Atsushi Ochiai
{"title":"Tumors Originating from Fat Tissue in the Head and Neck Area: A Review of 40 Cases","authors":"Atsushi Ochiai","doi":"10.26717/bjstr.2022.41.006589","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006589","url":null,"abstract":"Originating from Fat Tissue in the Head and Neck Area: A Cases. Prognosis Objectives: To clarify the features of lipomas that had been operated on in Kitasato University Hospital (KUH) and diagnosed by reviewing a series of cases. Method: All patients having undergone tumor removal between January 2000 and December 2021. Patients were identified through pathology department records. Results: Ages ranged from 2 to 80 years, with an average age of 47.1 years. Lipomas were benign in 38 cases and malignant in 2 cases. All 38 lipomas required only surgery. In cases of lipoma, 3 cases developed complications after surgery. In the cases of lipoma, although postoperative results were varied and changing, there were no recurrences. Conclusion: Clinical files were reviewed for 40 patients. Lipomas were benign in 38 cases and malignant in 2 cases. Complications after surgery were seen in 3 cases. Although treatment requires total removal, in some cases require preoperative","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81890239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Diabetes Insipidus and Other Complications in Early Period After Pituitary Surgery: Analysis of 259 Patients 垂体术后早期尿崩症及其他并发症259例分析
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-01-25 DOI: 10.26717/bjstr.2022.41.006581
E. Gormolysova
{"title":"Prevalence of Diabetes Insipidus and Other Complications in Early Period After Pituitary Surgery: Analysis of 259 Patients","authors":"E. Gormolysova","doi":"10.26717/bjstr.2022.41.006581","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006581","url":null,"abstract":"Eugeniya Galina Moisak. Prevalence of Diabetes Insipidus and Other Complications in Early Period After Pituitary Surgery: Analysis of 259 Patients. Biomed The purpose of this study was to describe complications associated with the endoscopic transsphenoidal approach and to determine a relation between postoperative central diabetes insipidus (DI) and the characteristics of adenomas. Methods: Results:","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83693502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Post-ACL Rupture Integrated Rehabilitative Pathway: Factors Influencing Economic Resources Absorption 前交叉韧带断裂后综合康复途径:影响经济资源吸收的因素
Biomedical Journal of Scientific & Technical Research Pub Date : 2022-01-20 DOI: 10.26717/bjstr.2022.41.006564
L. Ferrario
{"title":"Post-ACL Rupture Integrated Rehabilitative Pathway: Factors Influencing Economic Resources Absorption","authors":"L. Ferrario","doi":"10.26717/bjstr.2022.41.006564","DOIUrl":"https://doi.org/10.26717/bjstr.2022.41.006564","url":null,"abstract":"To investigate the drivers that might influence the patient’s integrated rehabilitative pathway, after the rupture of the anterior cruciate ligament (ACL), in terms of economic resources absorption. Materials and Methods: An observational study, conducted in two private rehabilitation hospitals located in Italy, was conducted to obtain real-world data concerning the integrated rehabilitative pathway of 118 patients. Patients’ data were analysed adopting three methodological approaches. the predictors of the dependent variable. statistical approaches, comparative-configurational Results: Results reported that older age (β=0.145, p=0.049), higher sportiness level (β=0.169, p=0.022), as well as the length of the integrated rehabilitative pathway (β=0.550, p-value=0.000) and the performance of threshold tests (β=0.389, p-value =0.000) are antecedents of higher management costs (Adjusted R²=0.703 and F=24.482). Summarizing QCA results, age, and the level of sportiness of patients, in combination with the compliance, play an important role in the emergence of the selected and analyzed management costs. Conclusions: Findings could be useful for the optimization of integrated rehabilitative pathway, thus becoming more efficient and effective, guaranteeing a process personalization, consistent with efficiency-driven and cost-containment strategies.","PeriodicalId":9035,"journal":{"name":"Biomedical Journal of Scientific & Technical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86833327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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