Rajib Saha Rony, Ahmed Hossain, Md Daharul Islam, Md Fazal Karim, Aminur Rahman, Sudipta Saha Jui
{"title":"Accuracy of transient elastography in Identifying fibrosis among patients with Chronic hepatitis b: a cross-sectional Observational study","authors":"Rajib Saha Rony, Ahmed Hossain, Md Daharul Islam, Md Fazal Karim, Aminur Rahman, Sudipta Saha Jui","doi":"10.3329/bjm.v34i3.68423","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68423","url":null,"abstract":"Background: Hepatitis B virus (HBV) infection is a significant global public health problem, affecting millions of people worldwide. Liver biopsy is the gold standard for assessing fibrosis but is invasive and carries post-procedural risks. Noninvasive tests to evaluate liver fibrosis are needed, and transient elastography is one such method. This cross-sectional observational study aimed to assess the accuracy of transient elastography in identifying fibrosis among patients with chronic hepatitis B. \u0000Methods: The study was conducted at the Department of Medicine and Hepatology, Sir Salimullah Medical College Mitford Hospital, Dhaka. The study subjects were patients diagnosed with chronic hepatitis B infection, both outpatient and inpatient cases. Data were collected from 25 patients using convenient and purposive sampling techniques. Demographic data, clinical examination, and relevant investigations were recorded in a structured case report form. Data were processed, registered, edited, computerized, and analyzed. \u0000Results: The study included 25 patients with a mean age of 26.8±6.5 years, predominantly male (80%). All patients were HBsAg positive, 12.0% were HBeAg positive, and 56.0% were antiHBe positive. The mean HBV DNA PCR was 1516293.4±7475976.3 IU/ml. The mean ALT level was 45.4±13.8 U/L. The mean liver stiffness measurement (LSM) was 7.5±2.3 kPa, with 64.0% of patients showing fibrosis stage F0-F1. The mean periportal +/- bridging necrosis was 2.92±1.58, intralobular degeneration and focal were 1.16±0.55, portal inflammation was 2.52±0.87, histological activity index was 6.6±2.2, and fibrosis score was 1.44±1.04. Positive correlations were observed between LSM and histological activity index (r=0.239; p=0.251) and between LSM and fibrosis score (r=0.107; p=0.612). \u0000Conclusion: Our study demonstrates that transient elastography provides a non-invasive, easy, and cost-effective method for identifying fibrosis in chronic hepatitis B patients, serving as a potential alternative to liver biopsy. \u0000Bangladesh J Medicine 2023; 34(3): 199-205","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90070955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ishrat Binte Reza, MA Zahiruddin, H. Ahasan, Quazi Tarikul Islam
{"title":"Sepsis, an Unusual Presentation of Typhoid Fever - A Case Report","authors":"Ishrat Binte Reza, MA Zahiruddin, H. Ahasan, Quazi Tarikul Islam","doi":"10.3329/bjm.v34i3.68437","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68437","url":null,"abstract":"Typhoid fever is an infection caused by Salmonella typhi. The common complications are intestinal perforation and typhoid encephalopathy. Cases of typhoid fever with sepsis and/or disseminated intravascular coagulation (DIC) are rarely reported. A 20 yr old male presented with grade fever, vomiting, diarrhoea.His Dengue NS1 was negative, procalcitonin was high,coagulation profile was altered and developed subclinical DIC along with septicemia within a short period of time which is very rare. Sepsis and DIC are rare complications of typhoid fever. Typhoid fever can be presented with profound bleeding manifestation other than gastrointestinal bleeding, since it is a common symptom of typhoid fever. Further research should be conducted to postulate association between typhoid fever and DIC. Here we reported an unusual case of sepsis which a caused by case of typhoid fever.\u0000Bangladesh J Medicine 2023; 34(3): 252-254","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"339 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78109729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Nazim Uddin, Md Daharul Islam, Mohammad Sarwar Alam, Md Ataur Rahman, Shazedur Rahman, Khorshed Minhajul Alam Mondle, S. M. M. Hasan, Ahmed Hossain
{"title":"Study of Left Ventricular Dysfunction In Type 2 Diabetes Mellitus Patients Without Known Co-Morbidities","authors":"Mohammed Nazim Uddin, Md Daharul Islam, Mohammad Sarwar Alam, Md Ataur Rahman, Shazedur Rahman, Khorshed Minhajul Alam Mondle, S. M. M. Hasan, Ahmed Hossain","doi":"10.3329/bjm.v34i3.68429","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68429","url":null,"abstract":"Background: Subclinical left ventricular dysfunction in type 2 diabetes mellitus (DM) patients may precede the development of symptomatic heart failure. Detecting this dysfunction early could potentially prevent its progression. However, there is a scarcity of studies on this topic in Bangladesh. Therefore, this study aimed to explore the left ventricular function status in type 2 DM patients without any known co-morbid conditions in a tertiary care hospital.\u0000Methods: A cross-sectional study was conducted at the Department of Internal Medicine in Sir Salimullah Medical College & Mitford Hospital over a one-year period. A total of 100 patients with a diagnosis of type 2 DM, meeting the inclusion-exclusion criteria, were enrolled. Written informed consent was obtained from each participant, followed by the collection of socio-demographic data, detailed clinical history, and routine investigations. Echocardiograms were performed on all participants to assess the presence of systolic and diastolic dysfunction using various modes. Data analysis was conducted using the statistical software SPSS 23.0.\u0000Results: The mean age of the study patients was 47.23±9.13 (SD) years, with the majority in the age group of 40-49 years (43%). Female patients accounted for 58% of the sample, while male patients comprised 42%. The frequency of left ventricular diastolic dysfunction (LVDD) was 65%. The presence of LVDD was associated with longer duration of diabetes mellitus, higher HbA1C levels, older age, and increased BMI (p<.05).\u0000Conclusion: The majority of type 2 diabetic patients in this study exhibited left ventricular diastolic dysfunction, with a prevalence of 65%. Further larger-scale studies are recommended to validate these findings.\u0000Bangladesh J Medicine 2023; 34(3): 229-234","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80359260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measuring and Comparing Cortical Surface Area of Paracentral Lobule in a Tertiary care Hospital, Bangladesh","authors":"Mahfuza Chowdhury, Monira Khatun, Aminur Rahman, Tunajjina Kawsar, Rezowana Naznin, Ferdausi Rab","doi":"10.3329/bjm.v34i3.68432","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68432","url":null,"abstract":"Background: The paracentral lobule is the area on medial surface of the cerebral cortex which extends from precentral sulcus to postcentral sulcus. Any trauma, tumor, or cerebral ischemia cause lesions of motor and sensory cortex of paracentral lobule. The result of this study is very important to the radiologists and neurosurgeons for diagnosis of above mentioned diseases and the practice of safe neurosurgery. This study was carried out to observe the cortical surface area of paracentral lobule in adult male and female Bangladeshi population,may help for future research.\u0000Methods: This cross- sectional study was conducted in the Department of Anatomy, Dhaka Medical College, Dhaka, during the period of January 2017 to December 2017. Total 70 adult Bangladeshi male &female people were selected, among them 35 male and 35 female, age ranging from 20-65 years. CT scan image of brain in mid sagittal view was used for this study. Data were analyzed by Unpaired Student’s ‘t’ tests.\u0000Results: The surface area of motor cortex of right and left paracentral lobule was significantly higher (p<0.01) in male.Surface area of sensory cortex of both paracentral lobule was significantly higher (p<0.05) in male than female.\u0000Conclusion: The present study reveals significant difference in morphological measurements of right and left paracentral lobule between male and female of adult Bangladeshi population.\u0000Bangladesh J Medicine 2023; 34(3): 235-238","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79680407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disseminated herpes zoster in an Immunocompetent patient on long-term Clozapine: case report","authors":"Nikhil Das, Farzana Hoque","doi":"10.3329/bjm.v34i3.68435","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68435","url":null,"abstract":"Disseminated herpes zoster is characterized by more than 20 herpetic lesions distributed across other body parts outside the affected dermatome. Disseminated herpes zoster occurs more frequently in immunocompromised patients and only a handful of case reports highlighted itsoccurrence in immunocompetent individuals. Clozapine use has been linked to decreased immune functioning, but no conclusive evidence to categorize clozapine as an immunosuppressive drug has been published. Here we report a case of a 65-year-old immunocompetent man on long-term clozapine who presented with vesicular lesions in a non-dermatomal distribution and was diagnosed to have disseminated zoster.\u0000Bangladesh J Medicine 2023; 34(3): 241-244","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81800510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Alamgir Hossain, Aminur Rahman, A. Agarwalla, Muhammad Jamil Ahmed, Abul Hasnat Md Russel, Shahjada Mohammad Dastegir Khan, Mohammad Moshiur Rahman, Biplab Paul, Pallab Kanti Saha, Z. Ali
{"title":"Paradoxical reactions in the form of Optochiasmatic arachnoiditis and stroke in An immunocompetent girl with tuberculous Meningitis- a case report","authors":"Md Alamgir Hossain, Aminur Rahman, A. Agarwalla, Muhammad Jamil Ahmed, Abul Hasnat Md Russel, Shahjada Mohammad Dastegir Khan, Mohammad Moshiur Rahman, Biplab Paul, Pallab Kanti Saha, Z. Ali","doi":"10.3329/bjm.v34i3.68433","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68433","url":null,"abstract":"The paradoxical response is characterized by clinical or radiologic worsening of pre-existing lesions or the appearance of new lesions following initiation of treatment for tuberculosis (TB). The paradoxical response has raised questions about the accuracy of the diagnosis, the potential for treatment failure, and the presence of an underlying disease, making it an important topic of care for clinicians. In this case report, we present the paradox reaction of a 14 year old girl diagnosed and treated for TB meningitis. This healthy immune girl is successfully treated with steroids, and we discuss the importance of treating the paradox of tuberculosis progression despite the use of effective anti-TB drugs.\u0000Bangladesh J Medicine 2023; 34(3): 245-251","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83700061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Answer to Medical Quiz - 1 Vol. 34(3) 2023","authors":"Aminur Rahman","doi":"10.3329/bjm.v34i3.68446","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68446","url":null,"abstract":"Abstract not available \u0000Bangladesh J Medicine 2023; 34(3): 262","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83207429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Quazi Tarikul Islam, Ishrat Binte Reza, Asif Ahmed
{"title":"Typhoid Dengue Co-infection: 2 Case Reports","authors":"Quazi Tarikul Islam, Ishrat Binte Reza, Asif Ahmed","doi":"10.3329/bjm.v34i3.68434","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68434","url":null,"abstract":"Dengue and typhoid fever are different entities with overlapping signs and symptoms. The resemblance of symptoms makes clinical diagnosis and treatment difficult. Both are major health problems mainly during monsoon. If they are not diagnosed timely and treated, outcome can be fatal. We report 2 cases of dengue virus co-infection with typhoid fever during this outbreak of dengue. The aim of this report was to create awareness about this co-infection\u0000Bangladesh J Medicine 2023; 34(3): 239-240","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91303077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scars of Experience: Unleashing Hope","authors":"Chowdhury H Ahsan","doi":"10.3329/bjm.v34i3.68443","DOIUrl":"https://doi.org/10.3329/bjm.v34i3.68443","url":null,"abstract":"Abstract not available\u0000Bangladesh J Medicine 2023; 34(3): 257-259","PeriodicalId":8721,"journal":{"name":"Bangladesh Journal of Veterinary Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75508561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}