发布求助
文献互助 智能选刊 最新文献

Neuropatologia polska最新文献

筛选
英文 中文
[Pelizaeus-Merzbacher disease]. (Pelizaeus-Merzbacher疾病)。
Neuropatologia polska Pub Date : 2019-11-14 DOI: 10.1007/978-1-4020-6754-9_12491
J. Dymecki, D. Markiewicz, Z. Adamczewska
{"title":"[Pelizaeus-Merzbacher disease].","authors":"J. Dymecki, D. Markiewicz, Z. Adamczewska","doi":"10.1007/978-1-4020-6754-9_12491","DOIUrl":"https://doi.org/10.1007/978-1-4020-6754-9_12491","url":null,"abstract":"","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"11 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50931397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 99
Verapamil reduces quinolinic acid-induced neuronal damage in rat hippocampus in vitro. 维拉帕米减轻喹啉酸诱导的大鼠海马神经元损伤。
Neuropatologia polska Pub Date : 1993-01-01
E Matyja, E Kida
{"title":"Verapamil reduces quinolinic acid-induced neuronal damage in rat hippocampus in vitro.","authors":"E Matyja,&nbsp;E Kida","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of the organic calcium channel blocker, verapamil, on quinolinic acid (QUIN) neurotoxicity in rat hippocampal cultures was studied. Verapamil and QUIN, both in 100 microns concentration, were added simultaneously to the culture medium. Ultrastructural analysis showed that verapamil was able to reduce typical QUIN-induced tissue damages. Especially, 3 and 7 days after exposure to the two agents, majority of both neurons and postsynaptic dendrites revealed normally appearing morphological features. The results support the suggestion of the important role of calcium entry in the development of QUIN neurotoxicity.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 1-2","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19198558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemiballismus in patient with blastic phase of chronic myelogenous leukemia. 慢性骨髓性白血病母细胞期患者偏瘫。
Neuropatologia polska Pub Date : 1993-01-01
P Nowacki, B Zdziarska, B Zyluk, I Jankowska-Kurek
{"title":"Hemiballismus in patient with blastic phase of chronic myelogenous leukemia.","authors":"P Nowacki,&nbsp;B Zdziarska,&nbsp;B Zyluk,&nbsp;I Jankowska-Kurek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report the clinical course and neuropathological findings in the case of hemiballismus due to leukemic infiltration of the subthalamic nucleus. The symptoms were observed in a 19-year-old patient with blastic phase of chronic myelogenous leukemia, two weeks before death, when what is called the \"critical point\" developed (white cell count beyond 100 G/l and thrombocytopenia less than 50 G/l). The investigation are considered to confirm the role of the \"critical point\" in the development of central nervous system leukemic complications.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 3-4","pages":"143-8"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18793363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ammon's horn changes in focal brain ischemia in humans. 人类局灶性脑缺血时阿蒙角的改变。
Neuropatologia polska Pub Date : 1993-01-01
J Rafałowska, D Dziewulska, E Dolińska
{"title":"Ammon's horn changes in focal brain ischemia in humans.","authors":"J Rafałowska,&nbsp;D Dziewulska,&nbsp;E Dolińska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neuronal changes in Ammon's horn were examined immunocytochemically in 20 patients aged from 51 to 101 years, deceased in the course of ischemic lesions localized within the area supplied by vessels derived from other then Ammon's horn vascularization (middle cerebral artery). Numerous neurons within various sector of the pyramidal layer, in the dentate gyrus, subiculum and entorhinal cortex were immunopositive in reaction with antibodies to serum proteins (albumin, IgG, alpha-1-antitrypsin), indicating their damage. The distribution of damaged Ammon's horn pyramidal cells differed from the location of injured Ammon's horn neurons in experimental investigations of brain ischemia and did not indicate a selective vulnerability of pyramidal cells in the human h1 area, corresponding to the CA1 sector in animals. Contrary to experimental material, changes in the human Ammon's horn are caused by numerous overlapping factors.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 3-4","pages":"115-25"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18793360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disturbances of cortical development. 皮质发育障碍。
Neuropatologia polska Pub Date : 1993-01-01
M Dambska
{"title":"Disturbances of cortical development.","authors":"M Dambska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The development processes coinciding in formation of cerebral cortex were presented. On this background may arise the cortical developmental abnormalities. The review of principal cortical malformations include the 1) agyria-pachygyria - lissencephaly type I, 2) polymicrogyria, 3) disorganized cortical structure - lissencephaly type II, 4) minor cortical developmental anomalies and 5) other cortical dysplasia syndromes. It will help to reconstruct the pathomechanism of cortical abnormal development from early occurring primary errors to late changes in which coincide necrotic lesions. The presented material illustrate the role of time of occurrence and intensity of damage in final result of pathologic developmental processes.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 3-4","pages":"105-14"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18794874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bovine spongiform encephalopathy in cattle mimics ultrastructurally experimental scrapie and Creutzfeldt-Jakob disease in rodents. 牛海绵状脑病在超微结构上模拟啮齿类动物的实验性痒病和克雅氏病。
Neuropatologia polska Pub Date : 1993-01-01
P P Liberski, R Yanagihara, G A Wells, D C Gajdusek
{"title":"Bovine spongiform encephalopathy in cattle mimics ultrastructurally experimental scrapie and Creutzfeldt-Jakob disease in rodents.","authors":"P P Liberski,&nbsp;R Yanagihara,&nbsp;G A Wells,&nbsp;D C Gajdusek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a comparison of the ultrastructural pathology of bovine spongiform encephalopathy, experimental scrapie in hamsters and a panencephalopathic model of Creuzfeldt-Jakob disease (CJD) in mice. Vacuoles in dendrites, intramyelinic vacuoles (myelin ballooning), dystrophic axons, phagocytic astrocytes and macrophages, differing in extent, were found in all three models. We conclude, that this axonal and myelin pathology is a phenomenon common to the three models of SSVE studied, and the differences between panencephalophatic CJD and polioencephalopathic BSE and scrapie are only quantitative.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 1-2","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19198555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of clinical death on inositol 1,4,5-trisphosphate in the rat brain. 临床死亡对大鼠脑内肌醇1,4,5-三磷酸的影响。
Neuropatologia polska Pub Date : 1993-01-01
A Kapuściński
{"title":"Effect of clinical death on inositol 1,4,5-trisphosphate in the rat brain.","authors":"A Kapuściński","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes of inositol 1,4,5-trisphosphate content in the rat brain have been evaluated by means of the radioimmunologic method during 5-min clinical death and up to 2 hrs after resuscitation. Ischemia produced a decrease of IP3 content in the brain on the average to 63% of the control values. IP3 concentration in the brain increased on the average to 197% of the control values at the 15th min after resuscitation, and decreased to 127% at the 60 min. Two hours after resuscitation the IP3 content in the brain again increased on the average to 187%. The new data on brain metabolism in the ischemic conditions and the role of IP3 as the second messenger and mediator of neuromodulation processes are discussed.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 1-2","pages":"91-6"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19199181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyclic GMP levels in the rat brain and plasma during clinical death and after resuscitation. 临床死亡和复苏后大鼠脑和血浆中环GMP水平的变化。
Neuropatologia polska Pub Date : 1993-01-01
A Kapuściński
{"title":"Cyclic GMP levels in the rat brain and plasma during clinical death and after resuscitation.","authors":"A Kapuściński","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes of cGMP content in the rat brain and plasma have been evaluated by means of the radioimmunologic method after 5-min clinical death and up to 2 hours after resuscitation. Ischemia produced a decrease of cGMP in the brain, however, at the 15th min after resuscitation a reversible significant rise of nucleotide concentration was noted. In plasma at the end of ischemia and in the postischemic period a significant decrease of cGMP level was observed. The mechanisms of cGMP regulation in the central nervous system and the significance of the obtained results are discussed.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 3-4","pages":"127-32"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18793361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare coexistence of congenital malformations in adult. 罕见的成人先天性畸形共存。
Neuropatologia polska Pub Date : 1993-01-01
J Rafałowska, D Dziewulska, Z Jamrozik
{"title":"Rare coexistence of congenital malformations in adult.","authors":"J Rafałowska,&nbsp;D Dziewulska,&nbsp;Z Jamrozik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coexistence of several developmental abnormalities in adults is very rare and often asymptomatic. In many instances appearance of clinical symptomatology is evoked by some additional factors, not related directly with the basic pathological process. In a 21-year-old oligophrenic man a progressive paresis of inferior limbs appeared in the course of the upper respiratory tract infection. During 5 days of hospitalization transient peripheral paresis of the right facial nerve, tetraplegia, sphincter and respiratory disturbances occurred. Guillain-Barré syndrome and subarachnoid hemorrhage were diagnosed. On autopsy hemorrhagic focus in the medulla and in the cervical and upper thoracic parts of the spinal cord was found. Microscopic examination revealed hypocellularity of the 2nd and 4th layers of the temporal cortex, presence of the central canal within the brain stem, and hemorrhagic focus in the medulla. Two malformations in spinal cord were revealed: intraspinal angioma extending from the C2 to the Th6 segments and diastematomyelia within Th11 and lumbar segments. Diastematomyelia, cortical hypocellularity and angioma composed of fetal, lacunar artery- and vein-like vessels, are related with different periods of the ontogenic development. Coexistence of these malformations indicates prolonged action of the pathogenic factor(s), both in the embryonic and fetal life.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 1-2","pages":"45-54"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19198559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravascular coagulation in the central nervous system in patients with acute myeloblastic leukemias. 急性髓母细胞白血病患者的中枢神经系统血管内凝血。
Neuropatologia polska Pub Date : 1993-01-01
P Nowacki, B Zdziarska
{"title":"Intravascular coagulation in the central nervous system in patients with acute myeloblastic leukemias.","authors":"P Nowacki,&nbsp;B Zdziarska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The frequency and distribution of intravascular coagulation (IVC) were studied in brains of 121 patients who had died due to acute myeloblastic leukemias type M1 or M2. The IVC within the brain was observed in 59% of cases, more frequently in patients treated with polychemotherapy, especially according to TAD or VAPA protocols. The microthrombi were found predominantly in capillaries and small venous vessels. IVC was more frequent in cerebral and cerebellar white matter and in the neighbourhood of lateral ventricles (hippocampus, thalamus). In patients who had developed brain hemorrhage in the course of primary neoplasmic disease IVC was very frequent phenomenon, thus IVC is considered to be an important factor in the development of CNS hemorrhages in myeloblastic leukemias, irrespective of thrombocytopenia related to bone marrow involvement.</p>","PeriodicalId":76212,"journal":{"name":"Neuropatologia polska","volume":"31 1-2","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19198562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信