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Egyptian journal of bilharziasis最新文献

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Preliminary studies on the anti-schistosomal effect of Ammi majus L. 虾蛄抗血吸虫作用的初步研究。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
W A Abdulla, H Kadry, S G Mahran, E H el-Raziky, S el-Nakib
{"title":"Preliminary studies on the anti-schistosomal effect of Ammi majus L.","authors":"W A Abdulla,&nbsp;H Kadry,&nbsp;S G Mahran,&nbsp;E H el-Raziky,&nbsp;S el-Nakib","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>AMMI MAJUS L., a plant belonging to the family Umbellifereae was found to possess a certain antischistosomal effect in mice infected with S. mansoni. This was proved by applying two techniques, the worm burden and the Oogram change. Bergapten, a pure furocoumarin naturally present in Ammi majus was found to have certain schistosomicidal effect.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11768349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunodiffusion studies on Schistosoma mansoni and its intermediate host stage specific antigens. 3. Immunoelectrophoresis cross-reactions between S. mansoni stages and Biomphalaria sp. hepato-pancreas antigens. 曼氏血吸虫及其中间宿主期特异性抗原的免疫扩散研究。3.mansoni S.分期与Biomphalaria sp.肝胰腺抗原的免疫电泳交叉反应。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
J Henning, G R Rizk, G Youssef, O Zwisler
{"title":"Immunodiffusion studies on Schistosoma mansoni and its intermediate host stage specific antigens. 3. Immunoelectrophoresis cross-reactions between S. mansoni stages and Biomphalaria sp. hepato-pancreas antigens.","authors":"J Henning,&nbsp;G R Rizk,&nbsp;G Youssef,&nbsp;O Zwisler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>IMMUNOELECTROPHORESIS was applied for cross-wise checking of the different stages in the life cycle of schistosoma mansoni with extracts of hepato-pancreas from its intermediate host snails Biomphalaria glabrata and Biomphalaria alexandrina. Only few fractions were common to non infected snail organ and parasite development stage, while more crossreactions were detected with infected snail hepato - pancreas.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"68-78"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11297887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary investigation of bilharzial patients for the presence of Australia antigen using latex agglutination test. 用乳胶凝集试验对bilharial患者进行澳大利亚抗原存在的初步调查。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
A A Ata, E H el-Raziky, A Gaber, Z A Shaker, A H el-Kalouby, S Z Eissa
{"title":"Preliminary investigation of bilharzial patients for the presence of Australia antigen using latex agglutination test.","authors":"A A Ata,&nbsp;E H el-Raziky,&nbsp;A Gaber,&nbsp;Z A Shaker,&nbsp;A H el-Kalouby,&nbsp;S Z Eissa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>THE AUSTRALIA antigen was studied by the use of a reversed passive latex agglutination test in the sera of 250 cases, mostly bilharzial. The results were analysed in relation to age, clinical presentation, bilharzial infestation, antibilharzial treatment, jaundice and serum bilirubin. It was found that, the test was significantly more positive in hepatosplenic cases, in those with past history of bilharziasis, in those with jaundice and in those with higher serum bilirubin level. While no significant difference was found in relation to age, and to history of antibilharzial treatment.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11850543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic effects of some antibilharzial drugs. Studies on the inhibitory action of "bilharcid" on succinate oxidation in normal rat liver. 一些抗结核药物的代谢作用。“胆酸”对正常大鼠肝脏琥珀酸氧化抑制作用的研究。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
A A Sharaf, A el-Sherbini, W A Abdulla
{"title":"Metabolic effects of some antibilharzial drugs. Studies on the inhibitory action of \"bilharcid\" on succinate oxidation in normal rat liver.","authors":"A A Sharaf,&nbsp;A el-Sherbini,&nbsp;W A Abdulla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>THE INHIBITION of succinate oxidation by Piperazine diantimonyl tartarate (Bilharcid) could be in part attributed to accumulation of oxaloacetate. This is discussed with reference to the effect of ATP, glutamate and cysteine on the reversal of the inhibitory action, of the drug on succinate oxidation.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"35-45"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11783663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunodiffusion studies on Schistosoma mansoni and its host stage specific antigens. 1. Immunoelectrophoresis cross-reactions between S. mansoni adults and larval stages antigens. 曼氏血吸虫及其宿主期特异性抗原的免疫扩散研究。1. 曼氏血吸虫成虫与幼虫抗原的免疫电泳交叉反应。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
G R Rizk, G Youssef, O Zwisler, J Henning
{"title":"Immunodiffusion studies on Schistosoma mansoni and its host stage specific antigens. 1. Immunoelectrophoresis cross-reactions between S. mansoni adults and larval stages antigens.","authors":"G R Rizk,&nbsp;G Youssef,&nbsp;O Zwisler,&nbsp;J Henning","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>IMMUNOELECTROPHORESIS was applied to evaluate the immunologic relationship between the different stages in the life cycle of Schistosoma mansoni (S.m.). The preparation of antigens and antisera was described. Separated female and male adult worms tested seem to be identical. Eggs, miracidia and cercariae from Biomphalaria glabrata and Biomphalaria alexandrina showed varying degree of cross-reactions. The maximal number of pricipitin arcs was observed, when anti-miracidia-serum was checked against all other S.m. antigens.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"53-62"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11297885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic effects of some antibilharzial drugs: inhibition of NAD-linked substrate oxidation in rat liver by bilharcid. 一些抗胆酸药物的代谢作用:胆酸对大鼠肝脏中nad1连接底物氧化的抑制作用。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
A A Sharaf, A el-Sherbini, W A Abdulla
{"title":"Metabolic effects of some antibilharzial drugs: inhibition of NAD-linked substrate oxidation in rat liver by bilharcid.","authors":"A A Sharaf,&nbsp;A el-Sherbini,&nbsp;W A Abdulla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>BILHARCID inhibited malate and pyruvate oxidation. The degree of inhibition reached 50% when the concentration of Bilharcid was 10(-3) M. The mechanisms of the inhibitory action of the drug are discussed with reference to the effects of both adenine and pyridine nucleotides on the activity of the oxidoreductase enzymes.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11422120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of hycanthone and niridazole on cholinesterase levels in experimental schistosomiasis. 噻虫酮和硝唑对实验性血吸虫病患者胆碱酯酶水平的影响。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
S K Hanna, M T Khayyal, S Saleh, F Farid, W A Abdulla
{"title":"Effect of hycanthone and niridazole on cholinesterase levels in experimental schistosomiasis.","authors":"S K Hanna,&nbsp;M T Khayyal,&nbsp;S Saleh,&nbsp;F Farid,&nbsp;W A Abdulla","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"5 1-2","pages":"101-12"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11758525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biochemical effects of niridazole. I. In vitro and in vivo effect of niridazole on the rate of gluconeogenesis and oxidation of pyruvate and some Krebs cycle intermediates in mice. 硝唑的生化作用。1 .硝唑对小鼠体内外糖异生速率及丙酮酸和某些克雷布斯循环中间体氧化的影响。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
A A Sharaf, M T Khayyal, A Kheir-el-Din, A A Sharaf, F Kassem
{"title":"Biochemical effects of niridazole. I. In vitro and in vivo effect of niridazole on the rate of gluconeogenesis and oxidation of pyruvate and some Krebs cycle intermediates in mice.","authors":"A A Sharaf,&nbsp;M T Khayyal,&nbsp;A Kheir-el-Din,&nbsp;A A Sharaf,&nbsp;F Kassem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of the antischistosomal drug, niridazole, on the rate of gluconeogenesis in kidney cortex slices and on the rate of oxidation of pyruvate and some Krebs cycle intermediates in liver homogenate of non infected mice were determined. In vitro, niridazole was found to inhibit the succinate and pyruvate oxidation at the high concentration tested (10(-3)M). The rate of gluconeogenesis from alpha-ketoglutarate was unaffected. In vivo, niridazole showed a stimulatory effect on the rate of gluconeogenesis from alpha-ketoglutarate and on the rate of oxidation of pyruvate at a dosage level of 100 mg/kg for 5 days. The observed changes were discussed and the differences observed between the in vivo and in vitro work were assumed to be due to exposure of the tissues to the unmetabolized drug in vitro and to the drug and its metabolites in vivo.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"5 1-2","pages":"49-57"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A preliminary report on materno-foetal immunological changes in schistosomiasis. II. Circulating antigens and antibodies. 血吸虫病母婴免疫变化的初步报道。2循环抗原和抗体。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
E H el-Raziky, Z A Shaker, A F Abbassy, F M Aboul-Ezz, Y A Naguib
{"title":"A preliminary report on materno-foetal immunological changes in schistosomiasis. II. Circulating antigens and antibodies.","authors":"E H el-Raziky,&nbsp;Z A Shaker,&nbsp;A F Abbassy,&nbsp;F M Aboul-Ezz,&nbsp;Y A Naguib","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty five pregnant simple bilharzial patients together with 8 non-bilharzial pregnant women and 14 bilharzial non-pregnant females were included in this study. Circulating bilharzial antigens were tested in all groups by the IHA technique. Both IHA and COP were used for detection of bilharzial antibodies in the same groups. Bilharzial antigenaemia was higher in pregnant bilharzial women than in non-pregnant ones. The bilharzial antibodies were detectable in a smaller percentage of bilharzial pregnant women than in non-pregnant ones. Also, the IHA antibody titers and COP grades were lower in the former than in the latter; a total picture suggestive of depressed humoral immune response in pregnant bilharzial women. The passage of circulating bilharzial antigens and antibodies through the placenta to the foetus is demonstrated.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"5 1-2","pages":"77-84"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of niridazole on the lipid pattern of the parasite and host tissues in experimental schistosomiasis mansoni. 硝立唑对实验性曼氏血吸虫病寄主及寄生虫脂质模式的影响。
Egyptian journal of bilharziasis Pub Date : 1978-01-01
M T Khayyal, A H Mousa, S Saleh, M A Abo-HASHISH, A A Metwally
{"title":"Effect of niridazole on the lipid pattern of the parasite and host tissues in experimental schistosomiasis mansoni.","authors":"M T Khayyal,&nbsp;A H Mousa,&nbsp;S Saleh,&nbsp;M A Abo-HASHISH,&nbsp;A A Metwally","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>THE LIPID pattern of blood and liver of mice infected with S. mansoni as well as in male and female worms was studied. Experiments were also carried out on non-infected and infected mice after treatment with Niridazole. It was found that Niridazole caused a significant increase in liver triglycerides and serum free acids. These changes were more pronounced in non-infected animals than in infected ones. The drug was found to reduce worm phospholipids and to increase their triglyceride level. The male worms were more affected than the female ones.</p>","PeriodicalId":75813,"journal":{"name":"Egyptian journal of bilharziasis","volume":"4 1","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11850545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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