Dakar medical最新文献_第10页

[Leg ulcer due to hydroxyurea. A case report]. 羟基脲引起的腿部溃疡。[病例报告]。

Dakar medical Pub Date : 2006-01-01

S B Gning, J M Debonne, N M Diagne-Guèye, B Ndiaye, F Fall, P S Mbaye

引用次数: 0

[Beckwith-Wiedemann syndrom: a case report in Dakar]. [Beckwith-Wiedemann综合征:达喀尔一例报告]。

Dakar medical Pub Date : 2006-01-01

O Ndiaye, S Diouf, A L Fall, A Sylla, M Guèye, A Ouattara, M G Sall, N Kuakuvi

引用次数: 0

[Mechanisms of action of acetonic and hexanic extracts of leaves of Vernonia colorata (Willd.) Drake (Composeae) on blod glucose regulation]. [中文]:长春花叶丙酮和己烷提取物的作用机制德雷克[作曲]血糖调节的研究。

Dakar medical Pub Date : 2006-01-01

G Y Sy, R B Nongonierma, A Cisse, A M Dieye, A Wele, N F Gadiaga, B Faye

{"title":"[Mechanisms of action of acetonic and hexanic extracts of leaves of Vernonia colorata (Willd.) Drake (Composeae) on blod glucose regulation].","authors":"G Y Sy, R B Nongonierma, A Cisse, A M Dieye, A Wele, N F Gadiaga, B Faye","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This study aimed to investigate the mechanism of action of acetonic and hexanic extracts of the leaves of Vernonia colorata on blood glucose regulation.Materials and methods: Experiments were performed in normoglycaemic, type 1 and 2 diabetic rats. The effects of acetonic and hexanic extracts on blood glucose were evaluated. The antagonism effect of hexanic extract on the decrease of blood glucose induced with glibenclamide and metformin was also tested.Results: The hexanic extract of the leaves of V. colorata (HELVC) dose dependently increased the blood glucose in normoglycaemic rats. At the dose of 30 and 100 mg/kg, the glycaemia varied from 0.84 +/- 0.02 to 1.11 +/- 0.10 g/l and 0.68 +/- 0.02 to 1.31 +/- 0.30 g/l (p<0.05, n = 5). Such glibenclamide, the acetonic extract of the leaves of V. colorata (AELVC) induced hypoglycaemia in normoglycaemic rats. The HELVC prevents significantly the AELVC and glibenclamide induced hypoglycaemia. The chronic administration of the AELVC and HELVC as well as glibenclamide in type 1 diabetic rats did not change significantly the level of blood glucose. In type 2 diabetic rats, the single dose administration of metformin (300 mg/kg, per os) decreased the glycaemia which is completely prevented by a HELVC pretreatment.Conclusion: These results suggest that: i) The respective hypo- and hyperglycaemic effects of AELVC and HELVC require the presence of the pancreatic beta cells. ii) The AELVC would act by a sulfonylurea-like mechanism as glibenclamide to induce an hypoglycaemic effect.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 1","pages":"42-6"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26213362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Seroprevalence of hepatitis C virus (HCV) in Senegalease blood donors]. [塞内加尔献血者丙型肝炎病毒(HCV)的血清患病率]。

Dakar medical Pub Date : 2006-01-01

T N Dieye, M Gadji, Y Cisse, T A Diallo, O Toure Falla, S Diop, S Diallo, D Thiam, L Diakhate

{"title":"[Seroprevalence of hepatitis C virus (HCV) in Senegalease blood donors].","authors":"T N Dieye, M Gadji, Y Cisse, T A Diallo, O Toure Falla, S Diop, S Diallo, D Thiam, L Diakhate","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Hepatitis C virus (HCV) is an important problem of public health in the world according to its transmission mode and its pathogenesis. The risk of blood transmission has led to be the systematic screening of blood donors in the world. In Senegal no study about HCV prevalence on the general population and also has been done. The aim of our study was to determine HCV prevalence in blood donors and the rate of co-infection with hepatitis B (HCV/HBV) or with HIV infection (HCV/HIV).Materials and methods: This study had been done in the National Blood Transfusion Centre (CNTS) in Dakar. Two different techniques has been used for the assessment HCV: 1/ ELISA technique and 2/ Immunoblot RIBA as confirmation test.Results: Our study relates to 1565 blood donors recruited in CNTS during 2002. 369 of them were new blood donors with 365 females and 1200 males. The mean average was 30.5 +/- 9.5 years, ranged from 18 to 59 years. HCV ELISA test were positive in 22 plasma samples and one of them were co-infected with hepatitis B (HCV/HBV). Four out of these 22 samples have been confirmed positive to RIBA test and three of them were not determined. HCV seroprevalence were 1.4% after ELISA and 0.25% after RIBA testing. This seroprevalence were similar in male and in female and higher in new blood donors than in regular blood donors.Conclusion: Our results reinforce the necessity to screen hepatitis C virus in all Senegalese blood transfusion centres.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 1","pages":"47-52"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26213363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hyperthyroidism surgery: experience of ENT department of hospital center of Thies]. 甲状腺功能亢进手术:三院中心耳鼻喉科经验

Dakar medical Pub Date : 2006-01-01

M Ndiaye, N Ndiaye, P N N Kouamo-Nandjou, R Deguenonvo, F Ndiaye, A Sy, B K Diallo, A Tall, I C Ndiaye, R Diouf, E M Diop

{"title":"[Hyperthyroidism surgery: experience of ENT department of hospital center of Thies].","authors":"M Ndiaye, N Ndiaye, P N N Kouamo-Nandjou, R Deguenonvo, F Ndiaye, A Sy, B K Diallo, A Tall, I C Ndiaye, R Diouf, E M Diop","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The treatment of hyperthyroidism includes different therapeutics means of which surgery. The objectives of this study were to evaluate the place of the surgery in the treatment of hyperthyroidism and to describes the complications.Patients and methods: It is a retrospective study on 22 patients treated by thyroidectomy from March 2002 to April 2004. The biological confirmation was systematic. A medical preparation has been done in all the cases. A total thyroidectomy has been done in 13 cases and a subtotal in 9 cases.Results: The mean age was 37 years. There were 20 women and 2 men. An euthyroidism has obtained after surgery. There complications were: 1/22 temporary palsy of recurrent nerve 1/22 acute hypoparathyroidism 1/22 post-operative death (haematoma)Conclusion: Surgery seems to be a good alternative to antithyroid agents, which are constraining and often ineffective in the long term, and to radioactive iodine who leads to a long follow-up because of induced hypothyroidy. With increasing surgical skill, the risk of recurrent or parathyroid injury is greatly decreased.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 3","pages":"136-40"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26827251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Efficiency of kangaroo care on thermoregulation and weight gain of a preterm newborn cohort in Dakar]. [袋鼠式护理对达喀尔早产儿体温调节和体重增加的影响]。

Dakar medical Pub Date : 2006-01-01

O Ndiaye, A Diouf, S Diouf, N N Diouf, A Cissé Bathily, C T Cissé, A Sylla, M Guèye, M G Sall, J C Moreau, N Kuakuvi

引用次数: 0

[Antibioresistance of Escherichia coli strains isolated from raw chicken meat in Senegal]. [从塞内加尔生鸡肉中分离出的大肠杆菌菌株的抗生素耐药性]。

Dakar medical Pub Date : 2006-01-01

A Fofana, R Bada Alambedji, M Seydi, A J Akakpo

{"title":"[Antibioresistance of Escherichia coli strains isolated from raw chicken meat in Senegal].","authors":"A Fofana, R Bada Alambedji, M Seydi, A J Akakpo","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Antimicrobial-resistant Escherichia coli and others pathogens bacteria can be transferred from animals to humans through consumption of contaminated food and foods products and thus present a public health risk. The increase in E. coli resistance to commonly used antimicrobials both in the public health and veterinary sectors is one of the major threats of health care worldwide. The present study was undertaken to estimate the antimicrobial resistance of E. coli isolates from raw chicken meat in Dakar.Material and method: Levying of skin and muscle have been carried out on 120 chicken carcasses bought from 13 sale points and 23 flocks beetween November 2003 and April 2004. 102 Escherichia coli strains have been isolated, among which, 90 were tested for their susceptibilities to 16 selected antibiotics by agar diffusion method.Results: All Escherichia coli strains (100%), were resistant to one or more antibiotic; 60 strains (66.66%) being resistant to more than five antibiotics. Those frequently encountererd are: ampicillin, trimethoprim, trimethoprim-sulfametoxazole, tetracycline, sulfonamides, streptomycin, nalidixic acid. Multiple resistances to 12 antibiotics were also observed. The lowest resistances were noted with gentamicin (3.33%) and neomycin (5.56%).Conclusion: This study showed the significance of chicken meat as source of Escherichia coli strains with a simple or multiple resistance to various antibiotics tested. Further studies are necessary in order to determine bacterium mechanisms of resistance.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26213365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Liquid chromatographic determination of free thiamine and its esters in whole blood]. 全血中游离硫胺素及其酯的液相色谱测定。

Dakar medical Pub Date : 2006-01-01

M Ake, Y N Soko, K A Malan

{"title":"[Liquid chromatographic determination of free thiamine and its esters in whole blood].","authors":"M Ake, Y N Soko, K A Malan","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: To appreciate vitamin B1 status in normal and pathophysiological states in local ivorian populations, a high-performance liquid chromatographic method for the simultaneous determination of thiamine and its phosphate esters: thiamine monophosphate and thiamine diphsophate or cocarboxylase in whole blood has been developed.Methods: The method involves extraction with diethylether, followed by pre-column alkaline derivatization by bromide cyanogen. The extract was analysed by isocratic reversed-phase isocratic high performance liquid chromatography with fluorescent detection. System suitability tests were applied to assess the method's continuing suitability for use. The main tests of method validation: linearity, precision, accuracy and sensibility were applied to the analytical procedure.Results: Thiamine and its esters were eluted within 10 minutes with a good resolution. System suitability tests showed that the chromatographic system was suitable for continuing use. Results of validation tests show the reliability of the method : linearity domain, satisfying precision and accuracy, detection limits between 0.067 pg/l et 0.92 pg/l (0.160 fmol/l et 1.822 fmol/l).Conclusion: The proposed method is suitable for determination of thiamine and its phosphate esters in whole blood.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 3","pages":"172-7"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26828687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Histopathological effects of neem products on larvae of Culex quinquefasciatus (Say, 1823) (Diptera: Culicidae)]. [印楝产品对致倦库蚊幼虫的组织病理学影响(双翅目:库蚊科)]。

Dakar medical Pub Date : 2006-01-01

R D Ndione, F Sèye, M Ndiaye, A I Sow

{"title":"[Histopathological effects of neem products on larvae of Culex quinquefasciatus (Say, 1823) (Diptera: Culicidae)].","authors":"R D Ndione, F Sèye, M Ndiaye, A I Sow","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Histopathological studies relating to last instars larvae of mosquitoes treated with neem products are very few. The objective were to study the action of Neem products on larvae mosquitoes of Culex quinquefasciatus.Materials and methods: The neem products (Neemix, Formulated neem oil, Pure neem oil and Neem powder) are tested on 4 instars larvae of Culex quinquefasciatus. Moribund and witness larvae were fixed, for histopathologic study.Results: The results showed the following facts: an intestinal epithelium, a bross border, a fat body and others tissues are normals at the level of the untreated larva; Fat body and muscle are not touched during the treatment of the larva with Pure neem oil; Intestinal epithelial cells slightly hypertrophied with beaches of lysis on the level of the larva treated with Neem powder; a lysis of the microvilli of brush border on the level of the witness-solvent; a destruction of the epithelial cells recorded in larva treated with a Neemix; a disappearance of the food column and a destruction of the epithelial cells remarked on the level of the larva treated with Formulated neem oil.Conclusion: The neem products used in this study have a Larvaecidal action on Culex quinquefasciatus larvae.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 2","pages":"107-12"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26832463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cranioencephalic complications of middle ear cholesteatoma: report of 4 cases]. 中耳胆脂瘤颅脑并发症4例报告

Dakar medical Pub Date : 2006-01-01

A Tall, M C Ba, I Essalki, B K Diallo, M Ndiaye, B Loum, I C Ndiaye, R Diouf, E M Diop

{"title":"[Cranioencephalic complications of middle ear cholesteatoma: report of 4 cases].","authors":"A Tall, M C Ba, I Essalki, B K Diallo, M Ndiaye, B Loum, I C Ndiaye, R Diouf, E M Diop","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Cranial and intracranial complications can be observed during middle ear cholesteatoma's evolution. We report our experience of management of infectious cholesteatoma's cranioencephalic complications.Material and methods: In a three year period, we had consecutively admitted 4 patients with cranioencephalic complications of middle ear cholesteatoma, in the Ear Nose and Throat (ENT) department of the university teaching hospital of Dakar. After preoperative investigations with computed tomography scan (CT scan) of brain and temporal bone. The patients had been operated after paraclinic assessment.Results: The finding showed one case of temporal bone otogenic extensive osteomyelitis with multifocal extradural empyema, 3 cases of brain abscess associated with subdural empyema and meningitis in 1 case. For 3 patients (75%), neurosurgical drainage and mastoidectomy were performed, associated with antibiotic treatment. The mastaidectomy was performed in the same time of the surgical procedure or delayed. One patient, with brain abscess, died before surgical intervention. With a follow up of 15 months, we have noticed stable mastoidectomies cavities and no neurological recurrence symptoms.Conclusion: These complications can be prevented by early treatment of chronic otitis media diseases. The appropriated management of these complications necessitate collaboration between otorhinolaryngologists and neuro surgeons.","PeriodicalId":75773,"journal":{"name":"Dakar medical","volume":"51 1","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26214062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0