Wilma F. Bergfeld , Angela M. Christiano , Maria K. Hordinsky
{"title":"Proceedings of the Ninth World Congress for Hair Research (2015)","authors":"Wilma F. Bergfeld , Angela M. Christiano , Maria K. Hordinsky","doi":"10.1016/j.jisp.2017.03.001","DOIUrl":"10.1016/j.jisp.2017.03.001","url":null,"abstract":"","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"18 1","pages":"Pages S1-S28"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jisp.2017.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35194003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Katikaneni, A. Seymour, Rohan Gulati, T. Ponnapakkam, R. Gensure
{"title":"Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain.","authors":"R. Katikaneni, A. Seymour, Rohan Gulati, T. Ponnapakkam, R. Gensure","doi":"10.1038/jidsymp.2015.32","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.32","url":null,"abstract":"","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"19 1","pages":"13-5"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75065502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rose Miller , Ruzica Z. Conic , Wilma Bergfeld , Natasha Atanaskova Mesinkovska
{"title":"Prevalence of Comorbid Conditions and Sun-Induced Skin Cancers in Patients with Alopecia Areata","authors":"Rose Miller , Ruzica Z. Conic , Wilma Bergfeld , Natasha Atanaskova Mesinkovska","doi":"10.1038/jidsymp.2015.44","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.44","url":null,"abstract":"<div><p>Alopecia areata is a multifactorial autoimmune disease causing non-scarring hair loss. Recent genome-wide association studies have pointed to connections between alopecia areata and other autoimmune disorders. Research of clinical conditions positively and negatively associated with alopecia areata is crucial for discovering the pathological mechanisms of disease and further treatment options.</p></div>","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"17 2","pages":"Pages 61-62"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/jidsymp.2015.44","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72102001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John P. Sundberg , Kevin McElwee , Michael A. Brehm , Lishan Su , Lloyd E. King Jr
{"title":"Animal Models for Alopecia Areata: What and Where?","authors":"John P. Sundberg , Kevin McElwee , Michael A. Brehm , Lishan Su , Lloyd E. King Jr","doi":"10.1038/jidsymp.2015.35","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.35","url":null,"abstract":"<div><p>Disease is not limited to humans. Rather, humans are but another mammal in a continuum, and as such, often share similar if not identical diseases with other mammalian species. Alopecia areata (AA) is such a disease. Natural disease occurs in humans, nonhuman primates, many domestic animals, and laboratory rodents. However, to be useful as models of human disease, affected animals need to be readily available to the research community, closely resemble the human disease, be easy to work with, and provide reproducible data. To date, the laboratory mouse (most if not all of the C3H substrains) and the Dundee experimental bald rat fit these criteria. Manipulations using full-thickness skin grafts or specific immune cell transfers have improved the models. New mouse models that carry a variety of genetic-based immunodeficiencies can now be used to recapitulate the human immune system and allow for human full-thickness skin grafts onto mice to investigate human-specific mechanistic and therapeutic questions. These models are summarized here including where they can currently be obtained from public access repositories.</p></div>","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"17 2","pages":"Pages 23-26"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/jidsymp.2015.35","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72101990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Big Data, Big Opportunities, and Big Challenges","authors":"Jeffrey A. Frelinger","doi":"10.1038/jidsymp.2015.38","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.38","url":null,"abstract":"<div><p>High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed us to investigate the genetics, gene expression, and impacts of the microbiome, there remain both practical and conceptual challenges. These include data handling, storage, and statistical analysis, as well as an inherent problem of the analysis of heterogeneous cell populations.</p></div>","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"17 2","pages":"Pages 33-35"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/jidsymp.2015.38","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72101994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine Chiang, N. Mesinkovska, M. Piliang, W. Bergfeld
{"title":"Clinical Efficacy of Diphenylcyclopropenone in Alopecia Areata: Retrospective Data Analysis of 50 Patients.","authors":"Katherine Chiang, N. Mesinkovska, M. Piliang, W. Bergfeld","doi":"10.1038/jidsymp.2015.28","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.28","url":null,"abstract":"","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"5 1","pages":"50-5"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74499983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}