Journal of Investigative Dermatology Symposium Proceedings最新文献_第10页

008 Vitamin D status in phototype VI Senegalese patients with systemic lupus erythematosus (SLE): A case control study 008系统性红斑狼疮（SLE）光照VI型塞内加尔患者的维生素D状况：一项病例对照研究

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2017-10-01 DOI: 10.1016/j.jisp.2016.10.010

F. Ly , H. Mansouri , S. Ndongo , H. Hakim , M.T. Diop Ndiaye , A. Diop , A. Diouf , F. Fall , N. Sall Diop

引用次数: 0

013 Prostaglandin D2 enhances testosterone metabolism by ROS-mediated altered redox potential in keratinocytes 013前列腺素D2通过ROS介导的角质形成细胞氧化还原电位的改变增强睾酮代谢

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2017-10-01 DOI: 10.1016/j.jisp.2016.10.015

Alon Mantel , John McDonald , Alice Pentland , Meena Katdare , Joanne Chan

引用次数: 0

Title Page/Disclaimer Statement 标题页/免责声明

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2017-01-01 DOI: 10.1016/S1087-0024(17)30014-X

引用次数: 0

Subscription Information 订阅信息

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2017-01-01 DOI: 10.1016/S1087-0024(17)30010-2

引用次数: 0

Proceedings of the Ninth World Congress for Hair Research (2015) 第九届世界头发研究大会论文集(2015)

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2017-01-01 DOI: 10.1016/j.jisp.2017.03.001

Wilma F. Bergfeld , Angela M. Christiano , Maria K. Hordinsky

引用次数: 0

Animal Models for Alopecia Areata: What and Where? 斑秃动物模型：什么和在哪里？

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2015-11-01 DOI: 10.1038/jidsymp.2015.35

John P. Sundberg , Kevin McElwee , Michael A. Brehm , Lishan Su , Lloyd E. King Jr

{"title":"Animal Models for Alopecia Areata: What and Where?","authors":"John P. Sundberg , Kevin McElwee , Michael A. Brehm , Lishan Su , Lloyd E. King Jr","doi":"10.1038/jidsymp.2015.35","DOIUrl":"https://doi.org/10.1038/jidsymp.2015.35","url":null,"abstract":"<div><p>Disease is not limited to humans. Rather, humans are but another mammal in a continuum, and as such, often share similar if not identical diseases with other mammalian species. Alopecia areata (AA) is such a disease. Natural disease occurs in humans, nonhuman primates, many domestic animals, and laboratory rodents. However, to be useful as models of human disease, affected animals need to be readily available to the research community, closely resemble the human disease, be easy to work with, and provide reproducible data. To date, the laboratory mouse (most if not all of the C3H substrains) and the Dundee experimental bald rat fit these criteria. Manipulations using full-thickness skin grafts or specific immune cell transfers have improved the models. New mouse models that carry a variety of genetic-based immunodeficiencies can now be used to recapitulate the human immune system and allow for human full-thickness skin grafts onto mice to investigate human-specific mechanistic and therapeutic questions. These models are summarized here including where they can currently be obtained from public access repositories.</p></div>","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"17 2","pages":"Pages 23-26"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/jidsymp.2015.35","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72101990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Big Data, Big Opportunities, and Big Challenges 大数据、大机遇和大挑战

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2015-11-01 DOI: 10.1038/jidsymp.2015.38

Jeffrey A. Frelinger

引用次数: 14

Prevalence of Comorbid Conditions and Sun-Induced Skin Cancers in Patients with Alopecia Areata 斑秃患者合并症和太阳诱发皮肤癌的患病率

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2015-11-01 DOI: 10.1038/jidsymp.2015.44

Rose Miller , Ruzica Z. Conic , Wilma Bergfeld , Natasha Atanaskova Mesinkovska

引用次数: 22

Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain. 与胶原结合结构域相关的甲状旁腺激素激动剂刺激毛发周期治疗小鼠斑秃。

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2015-11-01 DOI: 10.1038/jidsymp.2015.32

R. Katikaneni, A. Seymour, Rohan Gulati, T. Ponnapakkam, R. Gensure

引用次数: 8

The Use of the Immune Epitope Database to Study Autoimmune Epitope Data Related to Alopecia Areata 利用免疫表位数据库研究与斑秃相关的自身免疫表位数据

Journal of Investigative Dermatology Symposium Proceedings Pub Date : 2015-11-01 DOI: 10.1038/jidsymp.2015.39

Alessandro Sette , Sinu Paul , Kerrie Vaughan , Bjoern Peters

{"title":"The Use of the Immune Epitope Database to Study Autoimmune Epitope Data Related to Alopecia Areata","authors":"Alessandro Sette , Sinu Paul , Kerrie Vaughan , Bjoern Peters","doi":"10.1038/jidsymp.2015.39","DOIUrl":"10.1038/jidsymp.2015.39","url":null,"abstract":"<div><p>The Immune Epitope Database (IEDB) is a repository of published epitope data for infectious diseases, allergy, transplantation and autoimmunity. Herein we provide an introduction to the IEDB search interface, focusing on data related to autoimmune diseases, including alopecia areata (AA). We demonstrate how common questions related can be answered, such as how to search for specific autoantigens, epitope sequences, response types (B- and/or T-cell assays), or host, as well as how to search for epitopes of known major histocompatibility complex restriction and for data related to a specific disease. Our survey of the data found that while as a whole Autoimmunity-specific records represent a significant portion (∼30%); epitopes reported for AA are remarkably few, just 23 epitopes from six antigens. This reveals a significant knowledge gap for AA, and suggests that additional mapping of epitopes and identification of novel AA-associated autoantigens is warranted. Citing recently published examples, we show how bioinformatic, proteomic, and technological advances make it now increasingly feasible to identify epitopes and novel antigens in human disease. The goal herein was to increase awareness of the IEDB as a free resource for the scientific community and to demonstrate its use in finding (existing) and analyzing (prediction) epitope data.</p></div>","PeriodicalId":54791,"journal":{"name":"Journal of Investigative Dermatology Symposium Proceedings","volume":"17 2","pages":"Pages 36-41"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/jidsymp.2015.39","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7