Medical Ultrasonography最新文献

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Ultrasound guided interscalene brachial plexus block. 超声引导下锁骨间臂丛神经阻滞。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-09-29 Epub Date: 2023-02-07 DOI: 10.11152/mu-3885
Paschalitsa Serchan, Laura Griseto, Geraldine Armissoglio, Gabriella Iohom
{"title":"Ultrasound guided interscalene brachial plexus block.","authors":"Paschalitsa Serchan,&nbsp;Laura Griseto,&nbsp;Geraldine Armissoglio,&nbsp;Gabriella Iohom","doi":"10.11152/mu-3885","DOIUrl":"10.11152/mu-3885","url":null,"abstract":"<p><p>Peripheral nerve blocks have long been established as a crucial part of the enhanced recovery pathways after surgery. Interscalene brachial plexus block (ISB) is mainly indicated for anaesthesia and analgesia during shoulder and proximal arm surgery. Ultrasound technology has remarkably improved the efficacy and success rates of the ISB while limiting its potential complications.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":" ","pages":"347-351"},"PeriodicalIF":1.7,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9260662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of ultrasonography on learning curve and inter-subject performance variability in radial artery cannulation in standardized training for residents: a randomized controlled trial. 住院医师标准化训练中超声检查对桡动脉插管学习曲线和受试者间表现变异性的影响:一项随机对照试验。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 Epub Date: 2023-03-21 DOI: 10.11152/mu-3922
Li Shi, Yu Ju, Na Rui, Yuanyuan Cao, Tao Shan, Lihai Chen
{"title":"The efficacy of ultrasonography on learning curve and inter-subject performance variability in radial artery cannulation in standardized training for residents: a randomized controlled trial.","authors":"Li Shi,&nbsp;Yu Ju,&nbsp;Na Rui,&nbsp;Yuanyuan Cao,&nbsp;Tao Shan,&nbsp;Lihai Chen","doi":"10.11152/mu-3922","DOIUrl":"10.11152/mu-3922","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the effect of ultrasound (US) on learning curve and inter-subject performance variability of residents in radial artery cannulation.</p><p><strong>Material and methods: </strong>Twenty non-anesthesiology residents who received standardized training in an anesthesiology department were selected and divided into two groups: anatomy group or US group. After training of relevant anatomy, US recognition and puncture skill, residents selected 10 patients either under US or anatomical localization performing radial artery catheterization. The number and time of successful cases of catheterization were recorded, success rate of first attempt and catheterization, as well as the total success rate of catheterization were calculated. The learning curve and inter-subject performance variability of residents were also calculated. Complications and the residents' satisfaction for teaching and self-confidence before puncture were also recorded.</p><p><strong>Results: </strong>Compared to the anatomy group, total success rate and the success rate at first attempt were higher in US-guided group (88% vs. 57%, 94% vs. 81%). The average performance time in the US group was significantly less (2.9±0.8 min vs. 4.2±2.1 min) and the mean number of attempts was 1.6, while 2.6 for the anatomy group. With performing cases increasing, the average puncture time of residents in the US group decreased by 19s, while 14s in the anatomy group. More local hematoma occurred in the anatomy group. The satisfaction and confidence degree of residents were higher in US group ([98.5±6.5] vs [68.5±7.3], [90.2±8.6] vs [56.3±5.5]).</p><p><strong>Conclusion: </strong>US can significantly shorten the learning curve, reduce the inter-subject performance variability, improve the first attempt and total success rate of radial artery catheterization for non-anesthesiology residents.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"139-144"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9697002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing metatarsal chip fractures with ultrasound: faster and better. 超声诊断跖骨碎片骨折:更快更好。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-4040
Yu-Hsuan Chen, Chueh-Hung Wu, Levent Özçakar
{"title":"Diagnosing metatarsal chip fractures with ultrasound: faster and better.","authors":"Yu-Hsuan Chen,&nbsp;Chueh-Hung Wu,&nbsp;Levent Özçakar","doi":"10.11152/mu-4040","DOIUrl":"https://doi.org/10.11152/mu-4040","url":null,"abstract":"<p><p>.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"238-239"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Placental calcifications after coronavirus disease 2019 in first trimester of pregnancy: ultrasound and pathology findings. 妊娠早期冠状病毒病2019后胎盘钙化:超声和病理结果
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-3753
Insaf Kouba, Luis Bracero, Karmaine Millington, Matthew J Blitz
{"title":"Placental calcifications after coronavirus disease 2019 in first trimester of pregnancy: ultrasound and pathology findings.","authors":"Insaf Kouba,&nbsp;Luis Bracero,&nbsp;Karmaine Millington,&nbsp;Matthew J Blitz","doi":"10.11152/mu-3753","DOIUrl":"https://doi.org/10.11152/mu-3753","url":null,"abstract":"<p><p>The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on placental tissue is unclear. We present a case of symptomatic first trimester SARS-CoV-2 infection in which longitudinal ultrasound images demonstrated diffuse areas of echogenic foci. Her 39-week delivery, following an elective induction of labor, was uncomplicated, and placental pathol-ogy evaluation noted extensive calcifications. Such findings are sometimes seen in late and post-term pregnancies and those complicated by smoking, hypertensive disorders, diabetes, and viral infections. In this case, no other potential etiology was identified. Thus, we conclude that placental calcifications may be associated with SAR-CoV-2 infection in early pregnancy.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"233-235"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9747077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Is 3D ultrasound reliable for the evaluation of carotid disease? A systematic review and meta-analysis. 三维超声评价颈动脉疾病可靠吗?系统回顾和荟萃分析。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-3731
Salahaden R Sultan, Fatima T Bashmail, Nouf A Alzahrani, Shahd I Alharbi, Rayan Anbar, Mohammed Alkharaiji
{"title":"Is 3D ultrasound reliable for the evaluation of carotid disease? A systematic review and meta-analysis.","authors":"Salahaden R Sultan,&nbsp;Fatima T Bashmail,&nbsp;Nouf A Alzahrani,&nbsp;Shahd I Alharbi,&nbsp;Rayan Anbar,&nbsp;Mohammed Alkharaiji","doi":"10.11152/mu-3731","DOIUrl":"https://doi.org/10.11152/mu-3731","url":null,"abstract":"<p><strong>Aim: </strong>Studies assessing the use of 3D ultrasound (3DUS) for the evaluation of carotid disease reported varying views among observers about its reliability vis-à-vis 2DUS or angiography; ratings provided ranged from poor to excellent. Thisstudy aims to systematically review and analyze the reliability of 3DUS for the evaluation of carotid disease.</p><p><strong>Materials and methods: </strong>The PubMed database was searched for studies that evaluated carotid disease (i.e. plaque measurements and characteristics and degree of stenosis) using 3DUS.</p><p><strong>Results: </strong>Sixteen studies comprising a total of 918 stenosed carotids were reviewed and meta-analyzed. Data on intra- and inter-observer reproducibility and inter-method agreement (i.e. 3DUS vs 2D and 3DUS vs angiography) were analyzed. Overall analysis showed excellent intra- and inter-observer reproducibility (intraobserver: correlation coefficient r=0.88, 95% confidence intervals (CI) 0.84-0.92; intra-observer: r=0.91, 95% CI 0.87-0.95). The analysis also showed excellent agreement between 3DUS and 2DUS (r=0.89, 95% CI 0.83-0.95) and between 3DUS and angiography (r=0.73, 95% CI 0.44-0.1).</p><p><strong>Conclusion: </strong>3DUS has excellent intra- and inter-observer reproducibility and excellent agreement with 2DUS and angiography for the evaluation of carotid disease. Further studies assessing the reliability ofcarotid plaque characteristics using 3DUS in symptomatic and asymptomatic patients are required.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"216-223"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9684886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dynamic changes and prognosis of pulmonary congestion by lung ultrasound in hemodialysis patients: a systematic review and meta-analysis. 血液透析患者肺部超声检测肺充血的动态变化和预后:一项系统综述和荟萃分析。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 Epub Date: 2022-10-22 DOI: 10.11152/mu-3654
Jianan Zhou, Qi An, Xiukun Hou
{"title":"Dynamic changes and prognosis of pulmonary congestion by lung ultrasound in hemodialysis patients: a systematic review and meta-analysis.","authors":"Jianan Zhou,&nbsp;Qi An,&nbsp;Xiukun Hou","doi":"10.11152/mu-3654","DOIUrl":"10.11152/mu-3654","url":null,"abstract":"<p><strong>Aims: </strong>Lung ultrasound (LUS) has been rapidly developed to evaluate pulmonary extravascular fluid. A systematic review was conducted to study the dynamic changes of LUS findings of pulmonary congestion before and after hemodialysis and examine the application of LUS for the prognosis of hemodialysis patients.</p><p><strong>Material and methods: </strong>This study searched online databases for articles on hemodialysis patients that used LUS to evaluate dynamic changes during hemodialysis or prognosis. Articles published in English or Chinese until September 2021 with ≥30 patients were included in this study.</p><p><strong>Results: </strong>Of the 1329 articles, 14 met the inclusion criteria: 9 reported dynamic changes during dialysis in LUS (438 patients), and 5 reported the prognosis of hemodialysis patients in LUS (1274 patients). As indicated by a further meta-analysis, eight studies found that the combined standardized effect size was -0.74. The all-cause mortality rate of the dialysis patient group with high B-line scores was three times that of the dialysis patient group with low B-line scores. In dialysis patients, no difference was found between the LUS guided treatment and the conventional care in reducing the all-cause mortality (HR=0.92 95%CI: 0.67-1.27) and cardiovascular events (HR=0.98 95%CI: 0.72 -1.34).</p><p><strong>Conclusions: </strong>LUS can be used to effectively evaluate the volume status of hemodialysis patients in real time. The level of B-line before dialysis is significantly correlated with the poor prognosis. However, compared with the routine nursing group, the treatment of hemodialysis patients with LUS-guided volume management cannot effectively reduce mortality and cardiovascular events.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"208-215"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9693929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Combination of ultrasound-guided percutaneous A1 pulley release and intra-tendon sheath injection improves the therapeutic outcomes in adult trigger finger patients. 超声引导下经皮A1滑轮松解联合肌腱鞘内注射可提高成人扳机指患者的治疗效果。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-3877
Xingyou Zan, Wei-Ping Zhou, Yan Wang, Min Xu, Feng-Sheng Zhou, Xiang-Ming Fang
{"title":"Combination of ultrasound-guided percutaneous A1 pulley release and intra-tendon sheath injection improves the therapeutic outcomes in adult trigger finger patients.","authors":"Xingyou Zan,&nbsp;Wei-Ping Zhou,&nbsp;Yan Wang,&nbsp;Min Xu,&nbsp;Feng-Sheng Zhou,&nbsp;Xiang-Ming Fang","doi":"10.11152/mu-3877","DOIUrl":"https://doi.org/10.11152/mu-3877","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to use high-frequency ultrasound guidance to compare the efficacy of percutaneous release combined with intra-tendon sheath injection (PR-ITSI) and percutaneous release only (PR-ONLY) in the treatment of adult trigger finger (TF) patients.</p><p><strong>Materials and methods: </strong>A total of 48 patients were randomly divided into PR-ITSI group and PR-ONLY group. The thickness of the A1 pulley was measured prior to surgery and 1-year after surgery. Visual Analogue Scale (VAS) score and Patient Global Impression of Improvement (PGI-I) scale score of affected fingers were evaluated at 1 day, 1 month, and 1 year after surgery.</p><p><strong>Results: </strong>The overall difference of VAS score between the two groups after treatment was statistically significant (p<0.001), while the VAS scores gradually decreased in both groups at different time-points after treatment. The VAS scores in the PR-ITSI group at 1 day and 1 month after surgery were 1.475 and 0.904 (p<0.001), respectively, which were lower than those in the PR-ONLY group. Different treatment methods had no effect on the VAS score at 1 year after surgery (p=0.055). The thickness of the A1 pulley at 1 year after surgery was lower than that before surgery (p<0.001), whereas there was no significant difference in A1 pulley thickness between the two groups (p=0.095). The rate of PGI-I scale improvement by one grade at 1 day, 1 month, and 1 year after surgery in the PR-ITSI group was 15.322 times (95%CI: 4.466-52.573, p<0.001), 14.807 times (95%CI: 2.931-74.799, p=0.001), and 15.557 times (95%CI: 1.119-216.307, p=0.041), respectively, than that in the PR-ONLY group.</p><p><strong>Conclusion: </strong>Ultrasound-guided PR-ITSI is superior to PR-ONLY in the VAS score and PGI-I scale for adult TF patients.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"153-160"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semimembranosus muscle tear masquerading as a hypervascular tumor: ultrasonographic differential diagnosis for gluteal pain syndrome. 半膜肌撕裂伪装成高血管肿瘤:臀痛综合征的超声鉴别诊断。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-4115
Wei-Ting Wu, Kamal Mezian, Vincenzo Ricci, Ke-Vin Chang, Levent Ozcakar
{"title":"Semimembranosus muscle tear masquerading as a hypervascular tumor: ultrasonographic differential diagnosis for gluteal pain syndrome.","authors":"Wei-Ting Wu,&nbsp;Kamal Mezian,&nbsp;Vincenzo Ricci,&nbsp;Ke-Vin Chang,&nbsp;Levent Ozcakar","doi":"10.11152/mu-4115","DOIUrl":"https://doi.org/10.11152/mu-4115","url":null,"abstract":"<p><p>.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"241-242"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular function evaluation of the fetal heart: reference intervals and inter-observer variability of 2D speckle-tracking echocardiography measurements. 胎儿心脏左心室功能评价:参考间隔和2D斑点跟踪超声心动图测量的观察者间变异性。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-4021
Liliana Gozar, Maria Oana Sasaran, Daniela Toma, Andreea Cerghit-Paler, Claudiu Molnar-Varlam, Claudiu Mărginean, Vlăduț Săsăran
{"title":"Left ventricular function evaluation of the fetal heart: reference intervals and inter-observer variability of 2D speckle-tracking echocardiography measurements.","authors":"Liliana Gozar,&nbsp;Maria Oana Sasaran,&nbsp;Daniela Toma,&nbsp;Andreea Cerghit-Paler,&nbsp;Claudiu Molnar-Varlam,&nbsp;Claudiu Mărginean,&nbsp;Vlăduț Săsăran","doi":"10.11152/mu-4021","DOIUrl":"https://doi.org/10.11152/mu-4021","url":null,"abstract":"<p><strong>Aims: </strong>Measurement of myocardial strain using 2D speckle-tracking echocardiography can successfully quantify ventricular function, being considered superior to conventional echocardiography. This study aimed to establish reference intervals, interobserver agreements and reliability of two fetal echocardiographic parameters which reflect left ventricular myocardial function, left ventricular apical 4 chamber endo peak strain (AP4pLS) and ejection fraction (EF).</p><p><strong>Material and methods: </strong>We conducted a prospective study on 103 healthy fetuses. In each case, cardiac ultrasound images obtained were stored and afterwards were subject to offline 2D speckle-tracking echocardiographic analyses. In 15 randomly chosen subjects a second examiner also carried out an offline analysis of the 4-chamber view and the archived images, in order to assess inter-observer reproducibility and agreement level. Our study group was sub-divided into four different gestational age groups.</p><p><strong>Results: </strong>Reference ranges were established for the two measured parameters, AP4pLS and EF, which did not differ significantly between four different gestational age groups (p=0.98 and p=0.64) and neither correlated with gestational age progression (p=0.37 and p=0.08). An excellent level of agreement between the two examiners was found for the echocardiographic measurements, expressed through an intra-class correlation coefficient (ICC) value of 0.85 (0.62-0.94 for 95%CI) for AP4pLS and 0.78 (0.47- 0.92 for 95% CI) for EF.</p><p><strong>Conclusions: </strong>Speckle tracking AP4pLS and EF parameters are useful for assessment of ventricular myocardial function in healthy fetuses and can be reliably reproduced by two different skilled examiners. Further studies conducted on larger populations are required to standardize reference values of fetal speckle-tracking measurements.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"168-174"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound features combined with tumor-infiltrating lymphocytes for prediction of pathological response to neoadjuvant chemotherapy in breast cancer. 超声特征结合肿瘤浸润淋巴细胞预测乳腺癌新辅助化疗的病理反应。
IF 1.7 4区 医学
Medical Ultrasonography Pub Date : 2023-06-26 DOI: 10.11152/mu-3909
Yingying Jia, Xin Zhou, Yangyang Zhu, Xuewen Song, Ying Duan, Kundi Chen, Fang Nie
{"title":"Ultrasound features combined with tumor-infiltrating lymphocytes for prediction of pathological response to neoadjuvant chemotherapy in breast cancer.","authors":"Yingying Jia,&nbsp;Xin Zhou,&nbsp;Yangyang Zhu,&nbsp;Xuewen Song,&nbsp;Ying Duan,&nbsp;Kundi Chen,&nbsp;Fang Nie","doi":"10.11152/mu-3909","DOIUrl":"https://doi.org/10.11152/mu-3909","url":null,"abstract":"<p><strong>Aim: </strong>Neoadjuvant chemotherapy (NAC) plays an important role in the treatment and prognosis of breast cancer. The early identification of patients who can truly benefit from preoperative NAC is crucial in clinical practice. The purpose of this study was to explore whether the ultrasound features and clinical characteristics combined with tumor-infiltrating lymphocyte(TIL) levels can improve the performance of predicting NAC efficacy in breast cancer patients.</p><p><strong>Material and methods: </strong>In this retrospective study, 202 invasive breast cancer patients who underwent NAC followed by surgery were included. The baseline ultrasound features were reviewed by two radiologists. Miller-Payne Grading (MPG) was used to assess pathological response, and MPG 4-5 was defined as major histologic responders (MHR). Multivariable logistic regression analysis was used to evaluate independent predictors for MHR and build the prediction models. The receiver operating characteristic (ROC) curve was used to evaluate the performance of the models.</p><p><strong>Results: </strong>Of the 202 patients, 104 patients achieved MHR and 98 patients achieved non-MHR. Multivariate logistic regression analysis showed the US size (p=0.042), molecular subtypes (p=0.001), TIL levels (p<0.001), shape (p=0.030), and posterior features (p=0.018) were independent predictors for MHR. The model combined the US features, clinical characteristics, and TIL levels had a better performance with an area under the curve (AUC) of 0.811, a sensitivity of 0.663, and a specificity of 0.847.</p><p><strong>Conclusion: </strong>The model combined US features, clinical characteristics, and TIL levels had a better performance in predicting pathological response to NAC in breast cancer.</p>","PeriodicalId":48781,"journal":{"name":"Medical Ultrasonography","volume":"25 2","pages":"131-138"},"PeriodicalIF":1.7,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9698040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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