IP archives of cytology and histopathology research最新文献_第3页

Malignant struma ovarii- Report of a rare case 卵巢恶性肿瘤1例报告

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.046

Chhaya Shevra, Himanshu Kumar

{"title":"Malignant struma ovarii- Report of a rare case","authors":"Chhaya Shevra, Himanshu Kumar","doi":"10.18231/j.achr.2023.046","DOIUrl":"https://doi.org/10.18231/j.achr.2023.046","url":null,"abstract":"Struma ovarii is a highly specialized form of mature ovarian teratoma in which the ovary contains &#62;50% of thyroid tissue. It accounts for 1 – 3% of benign teratomas of the ovary. Malignant transformation is observed in 5-37% cases of struma ovarii. Peak age of incidence 4 - 5th decade with excellent prognosis. We report a rare form of malignant struma ovarii, composed of a follicular variant of papillary thyroid carcinoma with capsular invasion. A65-year-old hypertensive postmenopausal female presented with complaints of pain in abdomen, pelvic mass, frequent micturition, since 3 days. A pelvic sonogram showed an enlarged heterogenous right ovarian mass of sized 12 x 9 x 5 cm, with solid cystic lesion. Left ovary was unilocular and cystic of sized 5.5 x 4 x 3 cm. The uterus and cervix appeared to be normal. She underwent an exploratory laparotomy, and a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Based on histopathological and radiological features an impression of follicular variant of papillary carcinoma of thyroid with capsular invasion was favoured. : The patient was successfully treated with total abdominal hysterectomy with bilateral salpingo-oopherectomy. There are no sign of recurrence and metastasis two months after surgery. Patient is under regular follow up. : Malignant struma ovarii is a medical rarity and very few studies have been reported.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series 奥里萨邦西部三级卫生保健中心皮肤附件肿瘤的临床组织病理学研究-病例系列

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.051

Pragnya P. Mishra, Puspanjali Sahu, Sarita Panigrahi, Smruti Ranjan Hota, Priya Kumari, Premanand Panda

{"title":"A clinico-histopathological study of skin appendageal tumours in a tertiary health care centre in western Odisha– A case series","authors":"Pragnya P. Mishra, Puspanjali Sahu, Sarita Panigrahi, Smruti Ranjan Hota, Priya Kumari, Premanand Panda","doi":"10.18231/j.achr.2023.051","DOIUrl":"https://doi.org/10.18231/j.achr.2023.051","url":null,"abstract":"Skin appendageal tumours (SATs) are those neoplasms that arise from pilosebaceous, apocrine, or eccrine sweat glands. These are a diverse group of tumours with both benign and malignant counterparts. They can be single, multiple, or have a syndromic association with internal malignancies. Benign adnexal tumours are more common, while malignant adnexal tumours are rare, usually locally aggressive, and have the potential for nodal involvement and distant metastasis with a poor clinical outcome. Therefore, proper diagnosis of SATs is important for therapeutic and prognostic reasons. This study aims to determine the clinico-histopathological correlation in cases of SATs in our hospital. It is a case series conducted over a one-and-a-half year period from January 2021 to July 2022. All clinically suspected cases of SATs were examined, biopsied, and subjected to histopathological examination. Histopathologically confirmed cases of SATs were finally analysed. Among twenty-four thousand two hundred twenty-four new patients attending OPD, 30 suspected cases of ATs underwent histopathological examination. Histopathology was confirmatory in only 12 cases (40%). 10 cases were benign, and two were malignant. Out of 10 benign cases, hidradenoma was noted in 3 (25%), trichoepithelioma in 2 (16%), proliferating pilar tumour, apocrine hidrocystoma, steatocystoma multiplex, hidradenoma papilliferum, and pilomatrixoma were seen in one each. Females (75%) outnumbered males (25%) in our study population. : SATs are infrequent and are not frequently observed in the field of surgical pathology. Histopathology is the gold standard for diagnosis.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Androgen receptor study in children with hypospadias in comparison with children with normal genitalia 尿道下裂儿童与正常生殖器儿童雄激素受体的比较研究

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.044

RB Nerli, Shreyas Rai, Adarsh Sanikop, Shridhar Ghagane

{"title":"Androgen receptor study in children with hypospadias in comparison with children with normal genitalia","authors":"RB Nerli, Shreyas Rai, Adarsh Sanikop, Shridhar Ghagane","doi":"10.18231/j.achr.2023.044","DOIUrl":"https://doi.org/10.18231/j.achr.2023.044","url":null,"abstract":"Androgen receptors (ARs) have been localized to the penile skin, inner prepuce and urethra. Androgens play an important and vital role in the development of male urethra. Androgen signalling through the AR is critical for normal penile development. The objective of our study was to prospectively assess the AR staining score in children with hypospadias in comparison with children with normal genitalia. All children with hypospadias presenting to the Paediatric urological services for repair formed the study group. Children with normal genitalia and undergoing circumcision either for phimosis or for religious indications formed the controls. A piece of the foreskin was collected during surgery and were stained for immunohistochemistry. AR staining was expressed as an m-quick score. A total of 32 children (group I) underwent primary hypospadias repair and 24 children (group II) underwent circumcision during the study period. The mean m-quick score in patients with hypospadias was 219.96 and that of children undergoing circumcision was 90.04 (p &#60;0.050). AR is overexpressed in patients with hypospadias when compared with patients with normal genitalia. Similarly, AR is significantly overexpressed in patients with proximal hypospadias when compared with distal hypospadias.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteopetrosis presenting as Leukoerythroblastosis in 4 month old patient: A case report 4个月大的骨质疏松表现为白细胞增生症1例

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.049

Ranjana Hawaldar, Shana Nikhat Khan

引用次数: 0

Gastric duplication Cyst in a Child - An insight 儿童胃重复囊肿-一种见解

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.035

Dhiraj B Nikumbh, Sudhir Singhavi, Roopali D Nikumbh

引用次数: 0

Revisitation of thyroid lesions in natives from hilly region: A four years perspective 在丘陵地区本地人甲状腺病变的回顾:四年的观点

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.042

Brijesh Thakur, Jyotsna Bhateja, Sanjay Kaushik, Seema Acharya

{"title":"Revisitation of thyroid lesions in natives from hilly region: A four years perspective","authors":"Brijesh Thakur, Jyotsna Bhateja, Sanjay Kaushik, Seema Acharya","doi":"10.18231/j.achr.2023.042","DOIUrl":"https://doi.org/10.18231/j.achr.2023.042","url":null,"abstract":"Clinically palpable thyroid nodules pose a challenge in diagnosis and management for surgeons and pathologists as thyroid malignancies may show overlapping characteristics with their benign counterparts in terms of physical characteristics, hormonal levels and imaging details. This study was aimed to revisit the spectrum of thyroid lesions in surgically resected specimens, their clinicopathological characteristics and to compare the cytological and imaging findings in discrepant cases. The present retrospective study retrieved a total of 69 cases of thyroid resection specimens with available relevant demographic, clinicoradiological and cytological findings. The histopathological diagnosis was considered gold standard. Colloid goitre (37.7%) and papillary carcinoma (17.4%) were found to be the commonest non-neoplastc and neoplastic lesions respectively. Peak incidence in 20-40 years of age group and M:F ratio of 1:3.6 in overall thyroid disorders was noted. 08 discrepent cases were observed while comparing histological diagnosis with radiological and /or cytological findings. Histopathological diagnoses were in agreement with imaging findings and /or FNAC results in most of the cases, however, patients with indeterminate or suspicious FNAC results, need to be followed-up for early surgical intervention if required.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transitional meningioma benign who grade 1 tumor-A case and review of the literature 良性移行脑膜瘤1级肿瘤1例及文献复习

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.037

Sunil V Jagtap, Loknath Srimanto Sarkar, Shubham S Jagtap

{"title":"Transitional meningioma benign who grade 1 tumor-A case and review of the literature","authors":"Sunil V Jagtap, Loknath Srimanto Sarkar, Shubham S Jagtap","doi":"10.18231/j.achr.2023.037","DOIUrl":"https://doi.org/10.18231/j.achr.2023.037","url":null,"abstract":"Transitional meningioma (TM) is an uncommon benign meningioma. Transitional meningioma is a WHO grade I meningioma characterized by the coexistence of meningothelial cells and fibrous architectural patterns. A35 year female presented with history of intermittent fever, headache of 1 month duration. And since last 2 days with altered level of consciousness and vomiting. : MRI of the brain was performed using TI weighted spin echoI2 weighted turbo spin echo and turbo Fluid-attenuated inversion recovery: FLAIR diffusion sequences. It showed a large, lobulated, enhancing lesion in right fronto-temporal region, along right greater wing of sphenoid suggestive of meningioma. Surgical excision of tumor was done. On histopathology showed a benign tumor consists of meningothelial and fibrous proliferation. The meningothelial cells were arranged in fascicles, with the fibroblastic tumor in syncytial pattern. The nuclei were round, uniform without nucleoli. The chromatin was fine and open. The tumor cells were spindle having abundant pink cytoplasm, indistinguishable cell membranes and bland nuclear features. Mitotic figures and atypia were absent .Scattered Psammoma bodies were noted. Histopathological diagnosis was gives as benign WHO grade 1 tumor- transitional meningioma. Due to enhanced and improved imaging, histopathological techniques the increased incidence of meningiomas is observed and it will be helpful for better outcomes of patients. We are presenting this case of transitional meningioma benign tumor WHO grade1for its clinical, radioimaging and histopatholgical findings.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of pleomorphic adenoma of the nasal cavity 鼻腔多形性腺瘤1例

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.050

Puja Singh, Ranbeer Singh, Pooja Arora, Tejasvita Singh

引用次数: 0

Histopathological spectrum of fungal infections in COVID 19 cases – A retrospective observational study COVID - 19病例真菌感染的组织病理学谱——一项回顾性观察研究

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.041

Shilpa Mishra, Rakesh Rajiv Patkar

{"title":"Histopathological spectrum of fungal infections in COVID 19 cases – A retrospective observational study","authors":"Shilpa Mishra, Rakesh Rajiv Patkar","doi":"10.18231/j.achr.2023.041","DOIUrl":"https://doi.org/10.18231/j.achr.2023.041","url":null,"abstract":"A wide range of fungal and bacterial infections are associated with Corona virus disease (COVID19). There was a surge of mucormycosis during COVID19 pandemic in 2021. This study elaborates the histopathological findings observed in fungal infections of head and neck in COVID 19 patients. A retrospective observational study of histopathological findings of invasive fungal infection in COVID 19 case was conducted in our laboratory. All the tissue samples diagnosed as post COVID fungal infections during January 2021 to June 2021 were analyzed. Representative sections were taken and slides were stained with Hematoxylin & Eosin, Periodic Acidic Schiff (PAS) and Gomori Methenamine silver (GMS) stains. Histopathological features were studied. There were total 32 cases which had invasive fungal infections associated with COVID 19. The most affected age group was 31 to 50 years of age (50%), with male preponderance (87.5%). Diabetes was present in 62.5% cases, and steroid use during the treatment was present in 31.3% of the cases. The most common site was maxillary sinus (53.1%) followed by nasal cavity (34.4%). Isolated infection by mucor was seen in 68.8% cases, there were cases of secondary bacterial infection and candida with aspergillus infection. Angioinvasion was present in 56.3% cases and bone destruction in 15.6% cases. COVID 19 infection results in immune dysregulation and background of diabetes and over use of steroids increases risk of mucormycosis. An early histopathological diagnosis provides early diagnosis.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secretory carcinoma of breast: No more a juvenile tumor 乳腺分泌性癌:不再是幼年肿瘤

IP archives of cytology and histopathology research Pub Date : 2023-10-15 DOI: 10.18231/j.achr.2023.047

Meenakshi Mohapatro, Swati Smita Sahoo, Deepika Mishra, Milan Tripathy, Prasant Kumar Das, Fakir Charan Munda, Shushruta Mohanty, Alkananda Balbantray

{"title":"Secretory carcinoma of breast: No more a juvenile tumor","authors":"Meenakshi Mohapatro, Swati Smita Sahoo, Deepika Mishra, Milan Tripathy, Prasant Kumar Das, Fakir Charan Munda, Shushruta Mohanty, Alkananda Balbantray","doi":"10.18231/j.achr.2023.047","DOIUrl":"https://doi.org/10.18231/j.achr.2023.047","url":null,"abstract":": Secretory breast carcinoma (SBC) is one of the rare breast neoplasm with an incidence rate of &#60; 0.15% of all breast cancers. Previously it was described as juvenile breast carcinoma. Young children and adolescent girls are most commonly affected. It is characterized by balanced translocation t (12;15), ETV6-NTRK3 gene fusion. : A 45 -year-old female presented with palpable lump in left breast. FNAC was suggestive of mucinous carcinoma. The diagnosis of SBC was made through histopathology and Immunohistochemistry : Recent study report suggested that the disease may also occur at a later age group in contrast to the conventional thought of onset at juvenile age group. Long-term survival is good for these cases. In radiological studies of breast imaging it mimics a benign tumour Immuno-histochemistry and cytogenetic are of the tumour are the ancillary investigations for confirmation of diagnosis. : Although rare diagnosis of SBC can be confirmed by histopathological studies and IHC. It is slowly progressive but has a good prognosis.","PeriodicalId":479918,"journal":{"name":"IP archives of cytology and histopathology research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0