{"title":"The Role of Metallic Nanoparticles in the Prevention and Treatment of Parasitic Diseases in Poultry","authors":"Fatemeh Heshmati, Shimen Gevargiz Sangar, Amirmehdi Amoozadehsamakoosh, Elham Azadi, Nima Komeili","doi":"10.58803/jwps.v2i3.15","DOIUrl":"https://doi.org/10.58803/jwps.v2i3.15","url":null,"abstract":"The development of nanotechnology for the treatment of parasitic diseases is still in its infancy. However, it is expected that this new field can provide a solution to parasitic diseases and compensate for the lack of vaccines to prevent them. It can also provide new treatment options for parasitic diseases resistant to current treatments. Nanomaterials have been developed for antibacterial and anticancer therapies. However, it is important to determine their antiparasitic potential due to the wide variety of their physicochemical properties. When designing metallic nanoparticles (MeNPs) and specialized nanosystems like MeNPs encapsulated within a drug shell, it is essential to consider several key physicochemical properties. Shape, size, surface charge, and type of surfactant control are some of these physicochemical properties. In addition to interacting with parasite cells’ target molecules, shell molecules are also important. By developing antiparasitic drugs using nanotechnology and nanomaterials for diagnostics, new and effective methods of treatment and diagnostic tools for poultry diseases are expected to be available in the future to enhance poultry disease prevention and reduce morbidity and mortality rates.","PeriodicalId":477606,"journal":{"name":"Journal of World’s Poultry Science","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136235302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Giardiasis in Companion Birds in Mashhad, Iran","authors":"Farzin KazemiLifshagerd, Omid BehrouziNasab, Alireza Koochakzadeh, Majid Kazemnezhad","doi":"10.58803/jwps.v2i3.16","DOIUrl":"https://doi.org/10.58803/jwps.v2i3.16","url":null,"abstract":"Introduction: Giardia spp. are parasitic protozoans that infect the digestive system of ornamental birds, especially in Psittaciformes, with different prevalence in various species. Symptoms of Giardia infection vary from no noticeable signs in adult birds to poor growth, weakness, anorexia, ruffled feathers, and diarrhea in chicks. This study aimed to evaluate the prevalence of giardiasis in some parrots referred to a private veterinary clinic in Mashhad, Iran, during 2022. Case report: Feces of 215 birds suspected of being infected with Giardia spp. were collected. The birds were visited at one of the clinics in Mashhad, Iran, in 2022. Wet smear was prepared from their fresh feces and then sent to the laboratory department of the clinic for diagnosis. The parrots included adult cockatiels, cockatiel chicks, lovebirds, African grey parrots, and Green-cheeked parakeets. After the final diagnosis, metronidazole was administered orally at a dosage of 50 milligrams per kilogram of body weight every 12 hours for 5 consecutive days. Sick birds were tested again after the treatment to confirm they were parasite-free. The obtained results of the laboratory indicated 60 positive Cockatiels (47.6%), 10 positive cockatiel chicks (43.4%), 4 positive lovebirds (14.2%), 2 Green-cheeked parakeets (8.6%), and only 1 positive African grey parrot (6.6%). Among the positive cases, the severity of infection varied, with some birds showing severe, moderate, or mild infection levels. Upon a second examination, birds with mild and moderate contamination were found to be disease-free, while those with severe contamination required further treatment. Conclusion: The results suggested that treatment with metronidazole for 5 consecutive days was effective against mild to moderate infection in sick parrots. However, birds with severe conditions need to continue the treatment procedure.","PeriodicalId":477606,"journal":{"name":"Journal of World’s Poultry Science","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135887096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of Infectious Coryza in Canaries: Antibiotic Sensitivity and Clinical Outcomes","authors":"Alireza Koochakzadeh, Omid BehrouziNasab, Majid Kazemnezhad, Mahyar Yarahmadi Khorasani","doi":"10.58803/jwps.v2i2.14","DOIUrl":"https://doi.org/10.58803/jwps.v2i2.14","url":null,"abstract":"Introduction: Infectious coryza (IC) is a respiratory disease that affects poultry and other avian species. It is caused by Avibacterium paragallinarum. Common clinical signs of IC include rhinitis, facial swelling, anorexia, and retarded growth in young poultry. Case report: This report delves into a specific outbreak of IC among a herd of 120 ornamental canaries in Iran in February 2021, where 15 canaries succumbed to the disease. The canaries indicated symptoms, such as swollen heads, closed eyes, severe sinusitis, weight loss, loss of appetite, and reduced ovulation. After the necropsy, a clumpy discharge in the eyes and sinuses and minor bleeding were observed in the trachea. Samples from the sinuses of dead canaries were taken to the laboratory (Mashhad, Iran), and it was determined that the bacteria responsible for the deaths belonged to the genus Avibacterium. Avibacterium spp. are slow-growing and require a specific factor, Nicotinamide Adenine Dinucleotide (NAD), for growth. The antibacterial susceptibility of the bacteria was tested using 18 different antibiotics. Based on the results, fosfomycin and amikacin were selected for treatment. The birds were administered oral fosfomycin (160 milligrams per kilogram) and injection amikacin (10 milligrams per kilogram) for 7 consecutive days. However, a recurrence of symptoms was observed a week after the initial treatment (second outbreak), prompting a further 5 days of treatment. The isolate was completely sensitive to fosfomycin, trimethoprim-sulfamethoxazole, vancomycin, penicillin, amikacin, and furazolidone and the bacterium showed intermediate susceptibility to other antibiotics which tested. After 72 hours of treatment, casualties ceased, and clinical symptoms were reduced. Complete resolution of symptoms was observed within a week. In the second outbreak of the disease, no casualties occurred, and the symptoms vanished within 48 hours of initiating treatment. Conclusion: This case report underscored the infection of canaries flock by Avibacterium spp., which was sensitive to fosfomycin and amikacin in laboratory conditions, and and effectively facilitated the recovery of the infected birds in vivo. The antibiotic sensitivity test provided useful information for finding an effective treatment against bacterial infection, emphasizing the significance of collaborating with laboratories for optimal results. Furthermore, continuous monitoring of this isolate is imperative, as it may potentially play a role in upper respiratory disease outbreaks across diverse avian species.","PeriodicalId":477606,"journal":{"name":"Journal of World’s Poultry Science","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135842292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}