Anti-Aging Eastern Europe最新文献_第5页

INFLAMMAGING IN MUSCLE: THE MISSING LINK BETWEEN SARCOPENIA AND IDIOPATHIC INFLAMMATORY MYOPATHIES 肌肉炎症:肌肉减少症和特发性炎性肌病之间缺失的联系

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.10

K. Jagtap, L. Hoff, E. Conticini, R. Naveen, Latika Gupta

引用次数: 1

AGING AND ANTI-AGING RESEARCH AND PUBLISHING PRIORITIES 衰老和抗衰老的研究和出版重点

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.01

Oleksii Bashkirtsev, O. Zimba

引用次数: 1

POLYPHARMACY AS A THREAT TO AGING POPULATION 多重药房是人口老龄化的威胁

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.12

I. Benlidayı

引用次数: 0

NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS 神经性疼痛作为一个具有挑战性的临床实体在老年人

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.09

I. Benlidayı

引用次数: 0

AGE, AUTOIMMUNITY, AND INFLAMMATION: THE CURIOUS CASE OF IMMUNOSENESCENCE AND INFLAMM-AGING 年龄、自身免疫和炎症:免疫衰老和炎症老化的奇特案例

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.04

T. Sundaram, Sakir Ahmed

{"title":"AGE, AUTOIMMUNITY, AND INFLAMMATION: THE CURIOUS CASE OF IMMUNOSENESCENCE AND INFLAMM-AGING","authors":"T. Sundaram, Sakir Ahmed","doi":"10.56543/aaeeu.2022.1.1.04","DOIUrl":"https://doi.org/10.56543/aaeeu.2022.1.1.04","url":null,"abstract":"An ever-aging population has caused an increase in the prevalence of diseases which occur in the elderly like diabetes and cancer; and autoimmune disease like rheumatoid arthritis (RA). On the other hand, ageing also causes an increased susceptibility to infections, reactivation of latent infections and a poorer vaccine response. Together, this ageing-related decline in immunity is called immunosenescence and the associated ageing-related inflammation is called inflamm-aging. \u0000In this brief review, we describe the changes seen with ageing in innate and adaptive immunity and how these lead to the various peculiarities associated with ageing in the immune system. TEMRA cells, Senescence associated secretory phenotype (SASP) and exhausted T cells are the main changes that occur in ageing T cells. Age-associated B cells (ABCs) contribute to changes associated with autoimmunity in elderly. In the innate arm, the macrophages-led inflamm-aging cause an overall net pro-inflammatory state. However, the macrophages have reduced phagocytosis leading to accumulation of necrotic and apoptotic debris. \u0000We also attempt to explain how immunosenescence and inflamm-aging cause defective vaccine responses and an increased predisposition to autoimmune diseases. As the average life expectancy of the world continues to increase, this is not just a curiosity to study at whim, but an indispensable part of medicine in the near-future.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124190469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

OLEKSANDR BOGOMOLETS IS A VISIONARY OF ANTI-AGING IN UKRAINE Oleksandr bogomolets是乌克兰抗衰老的梦想家

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.06

B. Doskaliuk

引用次数: 3

THE ROLE OF PHYSICAL MEDICINE AND REHABILITATION IN LONG COVID-19 MANAGEMENT 物理医学和康复在COVID-19长期管理中的作用

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.02

B. Koçyiğit

{"title":"THE ROLE OF PHYSICAL MEDICINE AND REHABILITATION IN LONG COVID-19 MANAGEMENT","authors":"B. Koçyiğit","doi":"10.56543/aaeeu.2022.1.1.02","DOIUrl":"https://doi.org/10.56543/aaeeu.2022.1.1.02","url":null,"abstract":"COVID-19 is an infectious disease that can have a multi-system involvement, most notably, the respiratory tract. After acute infection, a considerable proportion of patients suffer from persistent symptoms and signs, defined as long COVID-19. Depending on the affected systems and organs, patients can experience various clinic pictures. Rehabilitation approaches serve a crucial role in providing functional recovery and improving quality of life for COVID-19 survivors. As a result of the wideness of the clinical spectrum of the long COVID-19, rehabilitation practices differ according to the affected systems. Therefore, the formation of multidisciplinary rehabilitation teams is an inevitable necessity. The establishment of specific centers for long COVID-19 rehabilitation will be beneficial. If it is not possible, existing rehabilitation centers should be strengthened for this purpose. Since the pulmonary system and respiratory tract are the most affected structures, one of the main issues to be considered in long COVID-19 cases is cardiopulmonary rehabilitation. Patients experience musculoskeletal disorders such as atrophy, sarcopenia, poor physical performance and contracture due to long-term hospitalization, intensive care treatment, quarantine practices and immobilization. Rehabilitation practices also focus on these disorders. All rehabilitation practices in long COVID-19 patients should start with low intensity, and parameters such as intensity and frequency should be increased as the patient's tolerance improves. In high-risk cases, parameters including oxygen saturation, blood pressure, and heart rhythm should be monitored. Health-care authorities should prioritize the rehabilitation of the long COVID-19 syndrome and invest in this area. Authorities, physicians and patients should collaborate to facilitate long COVID-19 rehabilitation and to establish a self-contained system.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125815958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

INFLAMM-AGING: A MECHANISM OF AGING THAT CONTRIBUTES TO THE CHARACTERISTICS OF SKIN INVOLVEMENT IN SYSTEMIC SCLEROSIS 炎症老化:一种老化机制，有助于皮肤参与系统性硬化症的特征

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.07

N. Gokcen

引用次数: 1

VITAMIN D AND AGING: AN INTERPLAY OF MULTIPLE MECHANISMS 维生素d与衰老:多种机制的相互作用

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.08

M. Goyal, Arun Kumar Kedia

引用次数: 0

IMMUNOSENESCENCE AND LATE-ONSET FAMILIAL MEDITERRANEAN FEVER 免疫衰老和晚发性家族性地中海热

Anti-Aging Eastern Europe Pub Date : 2022-06-28 DOI: 10.56543/aaeeu.2022.1.1.05

D. Cansu, C. Korkmaz

{"title":"IMMUNOSENESCENCE AND LATE-ONSET FAMILIAL MEDITERRANEAN FEVER","authors":"D. Cansu, C. Korkmaz","doi":"10.56543/aaeeu.2022.1.1.05","DOIUrl":"https://doi.org/10.56543/aaeeu.2022.1.1.05","url":null,"abstract":"Familial Mediterranean fever (FMF) is an autoinflammatory disease that causes recurrent fever and serositis. FMF often begins in childhood and is diagnosed at an early age. Although it is uncommon for the disease to occur after the age of 40, late-onset patient series have been published and compared to early-onset patient series in recent years. Although it is a genetically inherited disease, the reason why clinical symptoms appear at such a late age in some patients is unknown. The frequency of pathogenic mutations is lower in these patients than in early-onset FMF patients, and the disease has a milder course. Whether or not this clinical presentation is related to immune system changes associated with aging is an open question. Age-related immune system changes, such as an increase in senescence cells, the development of senescence-associated secretory phenotype, and a decline in autophagy with age, can trigger the inflammasome activation. In this regard, understanding the cause of the late-onset of FMF attacks may open up new avenues for research into pathogenesis. In this review, we will first compare the clinical features of the early and late-onset FMF series. We will then consider hypothetical causes of late-onset FMF attacks by reviewing age-related changes in the innate immune system.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"28 9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116292634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1