Current Journal of Neurology最新文献

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Validity and reliability of a questionnaire assessing the knowledge, attitude, and awareness in the informal caregivers of comatose patients: An observational study. 评估昏迷病人非正式照护者的知识、态度和意识的问卷效度和信度:一项观察性研究。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17544
Aishwarya Swaminathan, Sanjiv Kumar
{"title":"Validity and reliability of a questionnaire assessing the knowledge, attitude, and awareness in the informal caregivers of comatose patients: An observational study.","authors":"Aishwarya Swaminathan, Sanjiv Kumar","doi":"10.18502/cjn.v23i3.17544","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17544","url":null,"abstract":"<p><p><b>Background:</b> Comatose is a state of deep unconsciousness in an individual being unresponsive which has an impact on the informal caregivers providing care to their kinships. The validity and reliability of the domains of the Knowledge, Attitude, Awareness-Comatose Caregiver Questionnaire (KAA-CCQ) and has been taken into consideration as an outcome measure to assess the level of knowledge, attitude, and awareness among the caregivers of comatose patients. <b>Methods:</b> 68 informal caregivers above the age of 18 years related to comatose patients were included in the study. The self-developed KAA-CCQ was administered on the informal caregivers of comatose patients to assess the level of knowledge, attitude, and awareness regarding coma. Validity and reliability of the questionnaire were calculated by Spearman's rank correlation and Cronbach΄s alpha, respectively. <b>Results:</b> The reliability of all the three domains and the questionnaire was found to be 0.8 and the item correlation with respect to the domain was above 0.6 for the knowledge whereas it was above 0.6 for the attitude and awareness domains that justified the validity of the questionnaire, and also the questionnaire had an excellent reliability. <b>Conclusion:</b> The KAA-CCQ will be a suitable questionnaire to assess the knowledge, attitude, and awareness in the informal caregivers of comatose patients.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"144-151"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between serum levels of fibroblast growth factor-21 and the severity of migraine headache in patients undergoing sodium valproate treatment. 丙戊酸钠治疗患者血清成纤维细胞生长因子-21水平与偏头痛严重程度的相关性
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17600
Hamed Cheraghmakani, Mehrdad Afzalinezhad, Monireh Ghazaeian, Parham Mortazavi, Narges Karimi, Sahar Fallah
{"title":"Correlation between serum levels of fibroblast growth factor-21 and the severity of migraine headache in patients undergoing sodium valproate treatment.","authors":"Hamed Cheraghmakani, Mehrdad Afzalinezhad, Monireh Ghazaeian, Parham Mortazavi, Narges Karimi, Sahar Fallah","doi":"10.18502/cjn.v23i3.17600","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17600","url":null,"abstract":"<p><p><b>Background:</b> Mitochondrial metabolism disruption increases neuron excitability and reduces migraine attack threshold. This study investigates whether serum fibroblast growth factor-21 (FGF-21) levels in chronic migraine relate to headache severity and response to sodium valproate treatment. <b>Methods:</b> This pilot study involved 30 patients with chronic migraine treated with sodium valproate. Serum FGF-21 levels were assessed at baseline and after 12 weeks of treatment. Pain severity and disability were evaluated using visual analogue scale (VAS) and Migraine Disability Assessment (MIDAS). Paired t-test was used for the quantitative variables. The qualitative variables were evaluated using Pearson's chi-square test and Fisher's exact test. Moreover, correlation coefficients were calculated. A P < 0.05 was considered statistically significant. <b>Results:</b> Mean age of the patients was 42.9 ± 11.3 years. There was a significant reduction in headache severity between baseline and the end of the study regarding VAS scores (8.50 ± 1.50 vs. 5.30 ± 2.20, P < 0.001). The same reduction was observed in MIDAS during the study (61.20 ± 33.20 vs. 20.31 ± 17.07, P < 0.001). However, there was no significant changes in serum levels of FGF-21 over three months (299.53 ± 479.80 vs. 491.33 ± 456.64, P = 0.810), nor any relationship between these levels and headache severity scores (MIDAS: P = 0.658, VAS: P = 0.708). <b>Conclusion:</b> The results of this study did not show a significant correlation between FGF-21 serum levels and changes in VAS and MIDAS throughout the study. Further research on various mitochondrial pathways can provide valuable insights into the migraine pathophysiology and help identify more effective biomarkers for monitoring therapeutic regimens.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"170-175"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral anterior capsulotomy in a patient with severe obsessive-compulsive disorder: Case report. 双侧前囊切除术治疗重度强迫症1例。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17603
Sajad Shafiee, Abbas Tafakhori, Mohammad Sadra Nemati, Saeed Kargar-Soleimanabad, Sobhan Alipour-Kiasar, Reza Yazdani-Cherati, Ahmadreza Hojati-Marvast, Omid Ahmadvand
{"title":"Bilateral anterior capsulotomy in a patient with severe obsessive-compulsive disorder: Case report.","authors":"Sajad Shafiee, Abbas Tafakhori, Mohammad Sadra Nemati, Saeed Kargar-Soleimanabad, Sobhan Alipour-Kiasar, Reza Yazdani-Cherati, Ahmadreza Hojati-Marvast, Omid Ahmadvand","doi":"10.18502/cjn.v23i3.17603","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17603","url":null,"abstract":"","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"193-196"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relative frequency of primary headaches in patients with neuromyelitis optica spectrum disorder: A cross-sectional study. 视神经脊髓炎谱系障碍患者原发性头痛的相对频率:一项横断面研究。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17547
Mohammadreza Etemadifar, Masoud Etemadifar, Seyyed Ali Alaei, Mahdi Norouzi
{"title":"Relative frequency of primary headaches in patients with neuromyelitis optica spectrum disorder: A cross-sectional study.","authors":"Mohammadreza Etemadifar, Masoud Etemadifar, Seyyed Ali Alaei, Mahdi Norouzi","doi":"10.18502/cjn.v23i3.17547","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17547","url":null,"abstract":"<p><p><b>Background:</b> Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disease predominantly affecting the central nervous system (CNS). Headaches, although common in patients with multiple sclerosis (MS), have been less studied in NMOSD. This study aimed to investigate the prevalence, characteristics, and associated symptoms of headaches in patients with NMOSD. <b>Methods:</b> This cross-sectional study included 120 patients with NMOSD recruited from MS clinics in Isfahan City, Iran, between 2023 and 2024. Patients were assessed for headache prevalence and characteristics. An expert neurologist conducted examinations to exclude secondary causes of headaches and classified headache types according to the International Classification of Headache Disorders (ICHD-3). <b>Results:</b> Eighteen patients (15%) reported headaches, all of whom were women. The average age of these patients was 41.27 ± 11.33 years, and the average onset age of NMOSD was 34.60 ± 12.12 years. Of the 18 patients, 14 were diagnosed with migraine and 4 with tension headaches. Patients with migraine reported more severe pain (severity score: 6.00 ± 1.42) than those with tension headaches (4.20 ± 1.35). Headache onset was equally likely to occur before or after an NMOSD diagnosis. Significant associated symptoms included photophobia, phonophobia, and nausea in patients with migraine, with a substantial impact on occupational disability reported by 57% of migraine sufferers and 50% of tension headache sufferers. <b>Conclusion:</b> Headaches, particularly migraines, are prevalent in patients with NMOSD and significantly impact their quality of life (QOL) and occupational functioning. These findings emphasize the need for clinicians to recognize headache patterns in NMOSD for accurate diagnosis and effective management. Further longitudinal studies are warranted to explore causal mechanisms and develop targeted interventions.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"165-169"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular, speech, and swallowing problems in a 9-year-old boy: A rare case of polyneuritis cranialis. 9岁男童的眼部、言语及吞咽问题:一例罕见的颅多神经炎病例。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17602
Sara Memarian, Golazin Shahbodagh-Khan, Masood Ghahvechi-Akbari, Elham Pourbakhtyaran, Saeid Samimiat, Mahmoudreza Ashrafi, Morteza Heidari
{"title":"Ocular, speech, and swallowing problems in a 9-year-old boy: A rare case of polyneuritis cranialis.","authors":"Sara Memarian, Golazin Shahbodagh-Khan, Masood Ghahvechi-Akbari, Elham Pourbakhtyaran, Saeid Samimiat, Mahmoudreza Ashrafi, Morteza Heidari","doi":"10.18502/cjn.v23i3.17602","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17602","url":null,"abstract":"","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"189-192"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examination of intracranial arachnoid cysts in children, symptomatic or asymptomatic. 有症状或无症状儿童颅内蛛网膜囊肿的检查。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17546
Yiğithan Güzin, Safa Mete Dağdaş, Pınar Gençpınar, Figen Baydan, Özkan Alataş, Ümit Belet, Gamze Sarıkaya Uzan, Nihal Olgaç Dündar
{"title":"Examination of intracranial arachnoid cysts in children, symptomatic or asymptomatic.","authors":"Yiğithan Güzin, Safa Mete Dağdaş, Pınar Gençpınar, Figen Baydan, Özkan Alataş, Ümit Belet, Gamze Sarıkaya Uzan, Nihal Olgaç Dündar","doi":"10.18502/cjn.v23i3.17546","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17546","url":null,"abstract":"<p><p><b>Background:</b> Arachnoid cysts (ACs) are non-neoplastic, intracranial cerebrospinal fluid (CSF)-filled cavities lined with arachnoid membranes. Most of them are found incidentally and are asymptomatic. The aim of this study was to describe the clinical and demographic characteristics of ACs and to investigate the frequency of complications. <b>Methods:</b> ACs were classified as cerebral and cerebellar, and were evaluated according to location and size using the Galassi classification. <b>Results:</b> Evaluation was made of 103 patients with AC admitted to the pediatric neurology department. The patients comprised 62.1% boys and 37.9% girls with a mean age of 10.1 ± 4.9 years. Headache was present in 33% of patients, epileptic seizures in 22.3%, and neuromotor developmental delay in 14%. Spontaneous intracranial hemorrhage (ICH) was observed in 6 patients (5.8%), with 3 (50%) having a cyst diameter ≥ 5 cm. ACs frequently involved the retrocerebellar and temporal lobes. Epilepsy was diagnosed in 26 patients (25.2%) and in only one of them, epileptic discharge and AC originated from the same region. The risk of bleeding was found to be higher in patients with cyst diameter ≥ 5 cm (P = 0.032). <b>Conclusion:</b> Although ACs are generally considered harmless, a cyst size ≥ 5 cm is important in terms of the risk of bleeding and should be followed up regularly. Although it has been reported in the literature that ACs may be associated with epilepsy, no significant correlation was found between seizure type and electroencephalography (EEG) recordings in this study.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"159-164"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of interferon beta on quality of life in patients with multiple sclerosis: A systematic review and meta-analysis study. 干扰素对多发性硬化症患者生活质量的影响:一项系统回顾和荟萃分析研究。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17601
Mohammadreza Jamshidi, Milad Abbasian, Ali Ghasemnezhad, Atoosa Keshavarz-Motamed, Zehra Batool, Arian Tavasol, Mahsa Nikfarjam, Mohammad Moein Ashrafi, Atefeh Zare-Ahmadabadi, Seyyed Ali Jalalian
{"title":"The effect of interferon beta on quality of life in patients with multiple sclerosis: A systematic review and meta-analysis study.","authors":"Mohammadreza Jamshidi, Milad Abbasian, Ali Ghasemnezhad, Atoosa Keshavarz-Motamed, Zehra Batool, Arian Tavasol, Mahsa Nikfarjam, Mohammad Moein Ashrafi, Atefeh Zare-Ahmadabadi, Seyyed Ali Jalalian","doi":"10.18502/cjn.v23i3.17601","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17601","url":null,"abstract":"<p><p><b>Background:</b> Multiple sclerosis (MS) is one of the most common progressive neurological disorders affecting young adults. This study aimed to perform a meta-analysis on the effect of interferon beta (IFN-β) on the quality of life (QOL) of patients with MS. <b>Methods:</b> Using valid keywords and searching through databases like Medlib, ScienceDirect, PubMed, etc., 10 articles published between 1999 and 2020 were collected. The inclusion criteria were developed based on clinical guidelines, focusing on studies involving adults with MS treated with IFN-β, with outcomes measuring QOL. The exclusion criteria included studies not in English, those involving pediatric populations, or those lacking a control group. In the reviewed studies, 14 scales of QOL were measured at the beginning and the end of treatment with IFN-β. The data were analyzed using the random effects model meta-analysis method with R software and Stata software. Publication bias was not significant. Heterogeneity was evaluated using the Q test and the I<sup>2</sup> index. In heterogeneous studies, subgroup analysis and meta-regression were used for meta-analysis. The random-effect model was used for analyses with I<sup>2</sup> of more than 50%. <b>Results:</b> A total number of 1320 people with an average age of 32.40 ± 8.77 years were included in this study. On average, there was a slight decline in energy and satisfaction with sexual function scales (SSF), while a slight improvement was seen in the other 12 scales, following the treatment with IFN-β. However, no significant changes were observed in any of the QOL scales following treatment, except for health distress (HD) (P < 0.001), role limitation due to physical problems (RLPP) (P < 0.001), and role limitation due to emotional problems (RLEP) (P = 0.037), all of which showed a slight but natable improvement. The physical and mental components, showed significant increases of 0.189 [95% Confidence interval (CI): 0.083, 0.295, I<sup>2</sup> = 0%] and 0.221 (95% CI 0.119, 0.324, I<sup>2</sup> = 0%) in the scores after using IFN-β, respectively. <b>Conclusion:</b> This study's results showed that treatment with IFN-β does not negatively affect the QOL of patients with MS. Moreover, this treatment can slightly improve most QOL scales associated with the disability observed in MS.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"176-188"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hoarseness following heart valve replacement under general anesthesia: Bilateral tapia's syndrome as a rare cause. 全身麻醉下心脏瓣膜置换术后声音嘶哑:双侧tapia综合征是一个罕见的原因。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17629
Ilkin Iyigundogdu, Eda Derle, Fatma Irem Yesiler
{"title":"Hoarseness following heart valve replacement under general anesthesia: Bilateral tapia's syndrome as a rare cause.","authors":"Ilkin Iyigundogdu, Eda Derle, Fatma Irem Yesiler","doi":"10.18502/cjn.v23i3.17629","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17629","url":null,"abstract":"","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"197-198"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular lateropulsion in acute vestibular neuritis. 急性前庭神经炎的眼侧撕裂。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17604
Lisle Blackbourn, Maher Salem, Deepak Nair
{"title":"Ocular lateropulsion in acute vestibular neuritis.","authors":"Lisle Blackbourn, Maher Salem, Deepak Nair","doi":"10.18502/cjn.v23i3.17604","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17604","url":null,"abstract":"","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"199"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delirium among pediatric patients admitted to open-heart surgery intensive care unit: A cross-sectional study investigating a common challenge and concern, and its inciting factors. 心内直视手术重症监护病房儿科患者谵妄:一项横断面研究调查了一种常见的挑战和关注,及其刺激因素。
IF 0.5
Current Journal of Neurology Pub Date : 2024-07-05 DOI: 10.18502/cjn.v23i3.17545
Mohammadreza Mirzaaghayan, Sara Memarian, Alireza Abdshah, Mojgan Ghavami, Ghazale Roozbahani, Fatemeh Naseri, Mohammad Sajjad Jolani, Masood Ghahvechi, Behdad Gharib
{"title":"Delirium among pediatric patients admitted to open-heart surgery intensive care unit: A cross-sectional study investigating a common challenge and concern, and its inciting factors.","authors":"Mohammadreza Mirzaaghayan, Sara Memarian, Alireza Abdshah, Mojgan Ghavami, Ghazale Roozbahani, Fatemeh Naseri, Mohammad Sajjad Jolani, Masood Ghahvechi, Behdad Gharib","doi":"10.18502/cjn.v23i3.17545","DOIUrl":"https://doi.org/10.18502/cjn.v23i3.17545","url":null,"abstract":"<p><p><b>Background:</b> Delirium is a common challenge in pediatric open heart surgery intensive care units (OH-ICU). It is believed that emergence of delirium can lead to extended hospitalization periods. Therefore, we decided to investigate the association between delirium and its inciting factors in OH-ICU. <b>Methods:</b> This was a cross-sectional study on 92 pediatric patients admitted to OH-ICU of \"Children's Medical Center\" in Tehran, Iran, for more than 48 hours. To screen for delirium, the Cornell Assessment of Pediatric Delirium (CAPD ≥ 9) was utilized. Demographics, length of stay, development of complications, delirium, and factors associated with delirium were recorded. <b>Results:</b> We observed 34 (37%) cases of delirium in patients in OH-ICU. We had 51% male patients and 49% female ones, with a median age of 8 (0.2-144) months. The median length of mechanical ventilation was 11.5 hours (2-405) and they stayed in the hospital for a median of 4 days (2-31). The most common cardiac abnormality was ventricular septal defect (18%), associated with tetralogy of Fallot (TOF) (10%). Most of the patients (71%) experienced no adverse events during their stay; however, among those who did, vomiting and post-operation chorea were the most prevalent. Among the patients in our study, age [adjusted odds ratio (AOR) = 0.91], weight (AOR = 1.34), and sex (AOR = 0.31 for boys vs. girls) were significantly associated with delirium. <b>Conclusion:</b> We observed delirium in 37% of the patients. Development of delirium in patients admitted to pediatric intensive care unit (PICU) was associated with younger age, female sex, and higher weight.</p>","PeriodicalId":40077,"journal":{"name":"Current Journal of Neurology","volume":"23 3","pages":"152-158"},"PeriodicalIF":0.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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