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Brazilian Journal of Oncology最新文献

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Conhecimento de farmacovigilância no Brasil: percepção de participantes de um grupo de advocacy de pacientes de oncologia sobre informes de eventos adversos 巴西的药物警戒知识:肿瘤患者倡导小组参与者对不良事件报告的看法
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20180004
Guilherme Silva Julian, Renato de Oliveira, Eimy Minowa, L. Cecilio, Luciana de Barros
{"title":"Conhecimento de farmacovigilância no Brasil: percepção de participantes de um grupo de advocacy de pacientes de oncologia sobre informes de eventos adversos","authors":"Guilherme Silva Julian, Renato de Oliveira, Eimy Minowa, L. Cecilio, Luciana de Barros","doi":"10.5935/2526-8732.20180004","DOIUrl":"https://doi.org/10.5935/2526-8732.20180004","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127147318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic Factors Associated with the Efficacy of Hepatic Transarterial Embolization in Patients with Neuroendocrine Tumors 影响经动脉肝栓塞治疗神经内分泌肿瘤疗效的预后因素
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20190018
Jose Eduardo Nuñez, C. Zurstrassen, M. Barros, D. Uema, R. López, R. Riechelmann
{"title":"Prognostic Factors Associated with the Efficacy of Hepatic Transarterial Embolization in Patients with Neuroendocrine Tumors","authors":"Jose Eduardo Nuñez, C. Zurstrassen, M. Barros, D. Uema, R. López, R. Riechelmann","doi":"10.5935/2526-8732.20190018","DOIUrl":"https://doi.org/10.5935/2526-8732.20190018","url":null,"abstract":"Introduction: To evaluate the safety and efficacy of hepatic transarterial embolization (TAE) or transarterial chemoembolization (TACE) in patients with irresectable liver metastases from neuroendocrine tumors (NETs) treated at two Brazilian cancer centers. Methods: Retrospective multicenter analysis of patients (pts) with histological diagnosis of neuroendocrine tumor of any origin with unresectable and measurable hepatic metastases who underwent at least one procedure of TAE or TACE. Endpoints: Hepatic progression free survival (HPFS), overall survival (OS), tumor response and toxicity assessment. Results: Thirty-six pts were evaluated. Primary tumors were as follow: midgut 20 pts, pancreas 7 pts, others 9 pts. Most of patients had grade (G) 1-2 tumors (93.3%). In patients with functioning NETs, clinically significant symptomatic control was 41.7%. Concerning type of embolization (TAE vs TACE), there were no significant differences in the proportion of patients achieving reduction of at least 50% of 5HIAA (45.5% vs 50%) and radiological disease control rate (91.3% vs 92.3%), respectively. In a median follow up of 40.8 months (m), median HPFS was 38.9m, and mean OS was 98m (median not reached). No significant differences were found in HPFS or OS by type of embolization procedure. Pancreatic primary tumor and G3 tumor by WHO classification were associated with significantly shorter HPFS. Tumor G3 was also associated with shorter OS. Adverse events of any grade were: abdominal pain (13.8%), fever (5.5%), and 2 pts developed biloma. Conclusion: Our study is the first in our region reporting results of TAE/TACE in patients with irresectable liver metastases from NETs. We observed that pts with pancreatic or G3 NET derive less benefit from these procedures. In pts with G1-2 NETs, both techniques offer similar results. ABSTRACT","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129950695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group - GTG: Gastrointestinal Tumors 巴西胃肠道肿瘤小组- GTG:胃肠道肿瘤2018年回顾
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/1806-6054.20190014
A. Coutinho, G. Prolla, G. Fernandes, H. Salvador, R. Peixoto, R. Weschenfelder
{"title":"Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group - GTG: Gastrointestinal Tumors","authors":"A. Coutinho, G. Prolla, G. Fernandes, H. Salvador, R. Peixoto, R. Weschenfelder","doi":"10.5935/1806-6054.20190014","DOIUrl":"https://doi.org/10.5935/1806-6054.20190014","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123203380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group: Neuroendocrine Tumors 巴西胃肠道肿瘤组2018年回顾:神经内分泌肿瘤
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20190005
D. R. Filho, J. Rêgo, R. Riechelmann
{"title":"Year in Review 2018 by the Brazilian Gastrointestinal Tumors Group: Neuroendocrine Tumors","authors":"D. R. Filho, J. Rêgo, R. Riechelmann","doi":"10.5935/2526-8732.20190005","DOIUrl":"https://doi.org/10.5935/2526-8732.20190005","url":null,"abstract":"Neuroendocrine tumors (NET) constitute a heterogeneous group of neoplasms with variable prognoses and clinical presentations. Therefore their therapeutic management is challenging, involving a real multidisciplinary approach composed of medical oncologists, surgeons, endocrinologists, nuclear medicine physicians and interventionist radiologists. Here in this article, we have summarized the studies that have changed (or are likely to influence) the clinical management of patients with NET in 2018: the new WHO pathology classification for pancreatic NET, the use of peptide receptor radionuclide therapy (PRRT) in G3 NET, re-treatment with PRRT, randomized data on the CapTem regimen and new data on carcinoid heart disease. ABSTRACT","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123234869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tratamento do câncer avançado de próstata: Onde estamos em 2019? 晚期前列腺癌的治疗:2019年我们在哪里?
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20190001
F. J. S. Monteiro, A. Soares, Fernando Nunes Oliveira, Pedro Castilhos de Freitas Crivelaro, Pablo M. Barrios, A. P. Fay
{"title":"Tratamento do câncer avançado de próstata: Onde estamos em 2019?","authors":"F. J. S. Monteiro, A. Soares, Fernando Nunes Oliveira, Pedro Castilhos de Freitas Crivelaro, Pablo M. Barrios, A. P. Fay","doi":"10.5935/2526-8732.20190001","DOIUrl":"https://doi.org/10.5935/2526-8732.20190001","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122749370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic renal failure as initial presentation of pelvic hemangioendothelioma 盆腔血管内皮瘤的初始表现为慢性肾衰竭
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20210009
J. Braga, Fernanda Monteiro Orellana, A. Ziroldo, L. Sementilli, L. Toledo, R. Fernandes
{"title":"Chronic renal failure as initial presentation of pelvic hemangioendothelioma","authors":"J. Braga, Fernanda Monteiro Orellana, A. Ziroldo, L. Sementilli, L. Toledo, R. Fernandes","doi":"10.5935/2526-8732.20210009","DOIUrl":"https://doi.org/10.5935/2526-8732.20210009","url":null,"abstract":"Hemangioendothelioma is a rare vascular tumor whose etiology has not yet been defined. Currently, it is known to affect different sites, such as the abdominal-pelvic cavity. It is also known to present intermediate characteristics to hemangioma and angiosarcoma. In recent studies, 50-76% of patients are asymptomatic. Surgical treatment is indicated in most cases. The authors present a case of hemangioendothelioma with pelvic involve-ment and initial presentation as acute renal failure due to extrinsic ureteral compression, treated surgically, with histopathological diagnosis of hemangioendothelioma and recurrence after one year of the initial treatment presenting a histologically different form. This case illustrates a rare cause of lower urinary tract symptoms (LUTS), obstructive uropathy and acute renal failure and the appearance of two different tumors within a year, in line with the genetic/immunological factor in its genesis. ABSTRACT tumor vascular a cavidade abdominal e pélvica. Sabe-se que possui características intermediárias do hemangioma e do angios -sarcoma. Em estudos recentes, 50-76% dos pacientes são assintomáticos. O tratamento cirúrgico é indicado na maioria dos casos. Os autores apresentam um caso de hemangioen dotelioma com envolvimento pélvico e apresentação inicial como insuficiência renal aguda por compressão extrínseca ureteral, tratado cirurgicamente, diagnóstico histopatológico de hemangioendotelioma e recorrência após um ano do tratamento inicial, apresentando uma forma histologicamente diferente. Este caso ilustra uma causa rara de LUTS, uropatia obstrutiva e insuficiência renal aguda e o aparecimento de dois tumores diferentes dentro de um ano, em consonância com o fator genético/imunológico em sua gênese.","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126591821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous perirenal hematoma - foreshadowing of an impending renal cell carcinoma - does it need close surveillance? A case report and literature review 自发性肾周血肿——即将发生的肾细胞癌的前兆——是否需要密切监测?病例报告及文献复习
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20230376
Ankit Gupta, A. Singh, R. Sabnis
{"title":"Spontaneous perirenal hematoma - foreshadowing of an impending renal cell carcinoma - does it need close surveillance? A case report and literature review","authors":"Ankit Gupta, A. Singh, R. Sabnis","doi":"10.5935/2526-8732.20230376","DOIUrl":"https://doi.org/10.5935/2526-8732.20230376","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122193140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of trastuzumab therapy’s efficacy with or without pertuzumab combination in the metastatic HER2-positive breast cancer an oncology hospital of Pernambuco 在伯南布哥肿瘤医院，曲妥珠单抗联合或不联合治疗转移性her2阳性乳腺癌的疗效分析
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20220339
Kaline Nascimento dos Santos Lima, J. R. Cruz, Amanda Florentino Fonseca de Carvalho
{"title":"Analysis of trastuzumab therapy’s efficacy with or without pertuzumab combination in the metastatic HER2-positive breast cancer an oncology hospital of Pernambuco","authors":"Kaline Nascimento dos Santos Lima, J. R. Cruz, Amanda Florentino Fonseca de Carvalho","doi":"10.5935/2526-8732.20220339","DOIUrl":"https://doi.org/10.5935/2526-8732.20220339","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126009218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of EGFR family and p53 in a patient with Synchronous Primary Endometrial Adenocarcinoma and Clear Cell Renal Carcinoma: a Case Report EGFR家族和p53在同步原发性子宫内膜腺癌和透明细胞肾癌中的表达:1例报告
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20190011
P. F. Martins, Izabella Cristina Alves Souza, Ê. Ferreira, E. Veloso, T. Silveira, A. Underwood, F. C. Araújo, Helen Lima Del-Puerto
{"title":"Expression of EGFR family and p53 in a patient with Synchronous Primary Endometrial Adenocarcinoma and Clear Cell Renal Carcinoma: a Case Report","authors":"P. F. Martins, Izabella Cristina Alves Souza, Ê. Ferreira, E. Veloso, T. Silveira, A. Underwood, F. C. Araújo, Helen Lima Del-Puerto","doi":"10.5935/2526-8732.20190011","DOIUrl":"https://doi.org/10.5935/2526-8732.20190011","url":null,"abstract":"Braz J Oncol. 2019; 00(Supl): 0-00 1 Expression of EGFR family and p53 in a patient with Synchronous Primary Endometrial Adenocarcinoma and Clear Cell Renal Carcinoma: a Case Report Expressão da família EGFR e p53 em paciente com Adenocarcinoma Endometrial e Carcinoma Renal de Células Claras primários e sincrônicos: Relato de Caso Priscila Fernanda da Silva Martins1, Izabella Cristina Alves Souza1, Enio Ferreira2, Emerson Soares Veloso2, Tatiany L Silveira2, Adam Underwood3, Fabiano Conde Araujo4, Helen Lima Del-Puerto2","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"61 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114109838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The addition of PD-1/PD-L1 axis blockade to BRAF and MEK inhibition for advanced melanoma patients harboring BRAF mutations: a systematic review and meta-analysis 在BRAF和MEK抑制中加入PD-1/PD-L1轴阻断治疗BRAF突变晚期黑色素瘤患者:一项系统综述和荟萃分析
Brazilian Journal of Oncology Pub Date : 1900-01-01 DOI: 10.5935/2526-8732.20220298
M. F. Ribeiro, C. B. Xavier, A. Pereira, M. Scaranti, L. Faria, T. S. Corrêa, Marina Sahade, D. Q. Muniz, O. Feher, G. Fernandes, A. Katz, R. Munhoz
{"title":"The addition of PD-1/PD-L1 axis blockade to BRAF and MEK inhibition for advanced melanoma patients harboring BRAF mutations: a systematic review and meta-analysis","authors":"M. F. Ribeiro, C. B. Xavier, A. Pereira, M. Scaranti, L. Faria, T. S. Corrêa, Marina Sahade, D. Q. Muniz, O. Feher, G. Fernandes, A. Katz, R. Munhoz","doi":"10.5935/2526-8732.20220298","DOIUrl":"https://doi.org/10.5935/2526-8732.20220298","url":null,"abstract":"","PeriodicalId":395496,"journal":{"name":"Brazilian Journal of Oncology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115219831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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