Medicine Today最新文献

{"title":"Complications of Nd Yag Laser Capsulotomy","authors":"Md Abdul Matin, Md Mahbubur Rahman Shaheen, Zakia Farhana, Sajed Abdul Khaleque","doi":"10.3329/medtoday.v35i2.69173","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69173","url":null,"abstract":"Introduction: Aim and objective is to study the intra and post laser complications of Nd yag laser posterior  capsulotomy and to find out the incidence of complications. Materials and Methods: This study was conducted in the department of ophthalmology, Ad-Din Women Medical College 2, Bara moghbazar, Dhaka from July  2018 to June 2022. Our study included 206 patients of 220 eyes with significant PCO. Before laser capsulotomy all patients were assess by routine slit lamp examination, IOP measurement and posterior segment examination done for every patient for exclusion of gross posterior segment pathology. Nd yag laser capsulotomy was carried out under topical anesthesia. These patients were assessed for post laser visual acuity and complications  in 1st POD  after 7 day and 1 month. Every patients with post laser routine medications and as per need of other related eye problems. Result: Total 220 eyes  of 208 patients included in our study ,including 93 male (44.71%) and 115 female (55.29%).Range of age were 21yrs to 87 years. Laser capsulotomy were done  one  eye in 208 patients and both eyes in 14 patients. Range of energy used in our study from 1 to 4.5 mJ. Complications were noted after yag laser capsulotomy In 29 eyes (13.76%) though after taking maximum precaution for avoiding complications including pre laser slit lamp examination, assessment of IOP, proper dilatation of pupil, power setting were minimum as per as possible. Conclusion: The Nd yag laser capsulotomy is an effective, safe procedure for the treatment of opaque posterior capsule which is unique and magical approach for improvement of vision and restoration of effective life style. Every procedure have some adverse effect, Nd yag laser capsulotomy also have some complications .but benefit are tremendous if we can go in proper way. Medicine Today 2023 Vol.35(2): 91-94","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Outcome of Distal Tibial Fractures Fixed with Distal Tibial Locking Plate using MIPPO Technique","authors":"Nripen Kumar Kundu, Anwar Ahmed Miajee, Sathi Dastider","doi":"10.3329/medtoday.v35i2.69275","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69275","url":null,"abstract":"Introduction: Because of the extensive list of potential consequences, treating extra-articular distal tibia fractures is a daunting task for an orthopedic surgeon. This study was designed to evaluate the clinical and functional outcomes of minimally invasive plating for the treatment of distal tibial fractures. Materials and Methods: This prospective study was conducted at the Department of Orthopedic Surgery, Popular Medical College and Hospital, Dhaka during June 2021 to May 2022. A total of 20 patients with distal tibial fracture were selected for surgery and treated with minimally invasive plating. Afterwards, the patients' clinical and radiological outcomes were recorded. The ankle-hindfoot score developed by the American Orthopedic Foot and Ankle Society (AOFAS) was used to assess the functional outcomes. Results: In 15 of the 20 cases, radiological union took place between 18 and 22 weeks (mean 20.5 weeks); however, in 5 cases, union was delayed and required almost 26 weeks to establish. Four of the 20 cases experienced a superficial infection, while the remaining patients showed no further complications. According to the AOFAS score, our research showed that, out of 20 patients, 9 had excellent outcomes, 8 had good results, and 3 had acceptable results. Conclusion: Treatment of distal tibia fractures with locking plates by MIPPO technique is an effective method of therapy to achieve union and excellent functional results since it aids in the early restoration of ankle movement while reducing ankle stiffness. Medicine Today 2023 Vol.35(2): 114-117","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"37 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern, Severity and Outcome of Injuries Sustained in Road Traffic Accidents: A Tertiary Care Hospital-Based Study","authors":"Mohammad Ariful Islam, Md Aziz Ullah, Fatematul Jannat, Soma Rahman, Md Zillur Rahman","doi":"10.3329/medtoday.v35i2.69274","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69274","url":null,"abstract":"Introduction:Road Expansion and motorization, in the country has been accompanied by a rise in road accidents leading to road traffic injuries (RTIs). Today RTIs are one of the leading causes of deaths, disabilities, and hospitalizations with severe socioeconomic costs across the world. The aim of the study is to determine the pattern, severity and outcome of injuries amongst road traffic accident victims. Materials & Methods: An observational study was carried out at casualty department of Cumilla Medical College Hospital, from April 2020 to September 2020. Total 192 patients following RTIs were included in this study. After history taking, clinical examination and collection of investigation reports, data was analyzed by using SPSS-23. Results: Out of 192 patients, 33.3% of the patients belonged to age group 21-30 years, 71.4% were male. More than two third (67.2%) patients accident took place in high way and 62 (32.8%) in other areas. According to pattern of victims 111(57.8%) patients was found in pedestrian of victims, 48(25.0%) in driver and 33(17.2%) in passenger. In injury severity score, 98(51.0%) patients were found minor injuries followed by 57(29.7%) moderate, 22(11.5%) serious and 15(7.8%) severe injuries. Ninety (46.9%) patients were found transfer for definitive care followed by 52(27.1%) discharge after Rx, 30(15.6%) wound infection, 18(9.4%) referred to higher center and 2(1.0%) death. Conclusion: The present study shows that fatal accidents mainly affected the young adults in productive age groups and pedestrians. Highways were most commonly affected location. Most of the accidents caused by motorized vehicles. Medicine Today 2023 Vol.35(2): 109-113","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"35 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mystery of Tomato Flu in India","authors":"Taniqsha Bambani, Ashfaque Hossain","doi":"10.3329/medtoday.v35i2.69280","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69280","url":null,"abstract":"Introduction: While the globe fights against monkeypox and the coronavirus, a new virus known as \"Tomato flu\" threatens. This virus's recognized target is children. In May 2022, the virus was found for the first time in Kerala, India. Due to its principal symptom, tomato-shaped blisters all over the body, the ailment was given the term \"Tomato Flu.\" Recent reports described it as type of hand, foot and mouth disease (HFMD). It is easily diagnosed by a history and physical examination. It is an infectious condition, but there are still a lot of unanswered questions. To shed light on this topic, we decided to collect and summarize the information on this novel viral pathogen. Materials and Methods: To accomplish this, we undertook a thorough literature assessment of the Tomato Flu research that has already been done. We analyzed data from various sources such as medical journals, government reports and news articles to gain a better understanding of this emerging disease. In addition, we conducted interviews with healthcare professionals who have treated patients with Tomato Flu to gain insights into their experiences. Results: Survey of literature showed that Tomato Flu is a self-limiting disease. Children under the age of 5 and immunocompromised individuals are more susceptible to this disease. There is no diagnostic test for the disease, differential diagnosis involves typical symptoms and the absence of other known viral agents. There is no treatment, supportive care brings relief. Conclusion: Overall, this review provides a better understanding of Tomato Flu and its potential impact on public health. By shedding light on this emerging virus, we hope to contribute to ongoing efforts to prevent and treat of this infectious disease. Medicine Today 2023 Vol.35(2): 129-133","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"10 5-6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preterm Labour Pain & Its Outcome in 50 pts attending at a Tertiary Care Hospital-ICMH","authors":"Dr. Mahe Jabeen, Prof. Dr. Mossammat Dilruba, Prof. Anjuman Ara, Md Shabab Azmaeen, Mossammat Dilruba Akter, Anjuman Ara","doi":"10.3329/medtoday.v35i2.69167","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69167","url":null,"abstract":"Introduction: Preterm labor is the leading cause of neonatal morbidity all over the world. Over the past two decades despite major preventive efforts, the incidence of preterm birth has remained constant at about 5-10% of live births. The etiology is often multifactorial and poorly understood. Currently preterm labour is one of the most challenging problems confronting the obstetricians and perinatologists. With this background the present study was done to find out perinatal outcome in women presenting with preterm labour. Aims To study the fetal and maternal outcome in preterm labor cases. Materials and Methods: It was Prospective, single centered, observational study. A total of 50 women with preterm labor in the study period i.e. from June 2019 to May 2020 were included for the study sample. This study carried out at the department of Obstetrics and Gynecology, Institute of Child and Mother Health (ICMH), Matuail, Dhaka, Bangladesh. The data were collected personally through a structural questionnaire. Results: Out of 50 subjects, majority of mothers 32(64%) were in age group of 21-30 years followed by 12(24%) in age group of 20 years. Majority 26(52%) of study subjects were primigravida followed by 24(48%) multigravida. Majority 32(64%) of study subjects were in lower class followed by 15 (30%) cases in middle class, 3(6.0%) cases in affluent class. Maximum 31 (62%) cases were unbooked cases and rest 19 (38%) cases were booked. Out of 50 babies who were <2500 grams, maximum 29 (58.0%) were low birth weight followed by 11(22%) being VLBW babies. 5 cases were >2.5 kgs, which are not LBW babies according to WHO Classification of low birth weight. Majority 17 (47.2%) stayed for 1-10 days followed by 9 (25.0%) babies for 11-20 days. Also 7 (19.4%) babies stayed for 21-30 days. Conclusions: Preterm infants are at high risk of overall morbidity and mortality. Clinical suspicion, early detection and correction of risk factors, institutional delivery and good neonatal care back up facilities can improve the outcome of preterm labour and decrease the maternal complications as well. Medicine Today 2023 Vol.35 (2): 73-77","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"35 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Atorvastatin Plus Ezetimibe Therapy Versus Atorvastatin Monotherapy on Clinical Outcome in Acute ST-Segment Elevation Myocardial Infaction(STEMI)","authors":"Md Abdul Mukid, Md Shahabuddin, Farzana Tazin, Md Suhail Alam, Partha Sarathi Roy Chowdhury","doi":"10.3329/medtoday.v35i2.69175","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69175","url":null,"abstract":"Introduction: An acute ST-elevation myocardial infarction (STEMI) is an event in which transmural myocardial ischemia results in myocardial injury or necrosis. The current 2018 clinical definition of myocardial infarction (MI) requires the confirmation of the myocardial ischemic injury with abnormal cardiac biomarkers.  Acute coronary syndrome is the leading cause of death in the world and this is a consequence of unstable plaque due to dyslipidemia, reviewing with elevated LDL cholesterol. Reduction in LDL-c repeated clinical outcomes in patients with the acute coronary syndrome. Objective: To assess the effect of atorvastatin plus ezetimibe therapy versus atorvastatin monotherapy on clinical outcome in acute ST-Segment Elevation Myocardial Infaction(STEMI). Materials and Methods: A cross-sectional study was performed at dept. of Cardiology, Parkview Medical College, Sylhet, Bangladesh from June to December 2022. A total of 50 patients were evaluated in the study, including 42 patients with acute coronary syndrome with LDL-c levels≥70mg/dL at Can Tho Central General Hospital, we divided randomly into 2 groups: group A: control LDL-c by atorvastatin 40mg and ezetimibe 10mg; group B: control LDL-c by atorvastatin 40mg monotherapy. Then we compared the effect of control LDL-c between two groups after 10 follow-up days. Results: 50 patients with acute coronary syndrome: 60.0% male and 40.0% female, the average age was 66.03 ± 12.06 years, 82.0% LDL- c levels ≥7 mg/dL. After 10 days of treatment, the target LDL-c concentration in the group treated with atorvastatin 40mg+ ezetimibe 10mg was 48.1%, in the group treated with atorvastatin 40mg was 29.9% (p<0.05). Conclusions: LDL-c ratio reaches the target in the treatment group by atorvastatin 40mg + ezetimibe 10mg was 48.1% in the treatment group with atorvastatin 40 mg was 29.9% (p<0.05). From the results of our study, we recommend the combination therapy of atorvastatin and ezetimibe control LDL-c in patients with acute coronary syndrome better than atorvastatin monotherapy, thus physicians to treat patients with the acute coronary syndrome should combine early atorvastatin with ezetimibe since hospitalization. Medicine Today 2023 Vol. 35(2): 99-104","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"48 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disease Characteristics of Chronic Venous Disease in Referral Hospital in Bangladesh","authors":"Md Shamim Reza, Md Nazmus Sabah, Mst Tanzila Yasmin, Most Nusrat Zahan, Abul Hasan Muhammad Bashar, Md Moynul Islam, Md Mokhlesur Rahman, Shantonu Kumar Ghose","doi":"10.3329/medtoday.v35i2.69273","DOIUrl":"https://doi.org/10.3329/medtoday.v35i2.69273","url":null,"abstract":"Introduction:Chronic venous disease (CVD) is widespread, underdiagnosed, and can progress to chronic venous insufficiency and venous ulcer, which can require extensive treatment. This condition negatively impacts patient quality of life and place substantial burdens on healthcare resources. In Bangladesh this problem is increasing with very poor awareness. Materials and Methods: The prospective observational study was carried out in department of vascular surgery of National Institute of Cardiovascular disease. We randomly choose 180 patients with chonic venous disease (CVD) and evaluate their characteristics and prevalence of several types. Data collection started from May 2021 for next 6 months. Results: : The patients of this survey were aged between 24 to 70 years and the Mean±SD age was 43.6±12.2. 78.3% of total study population were male, 33.3% were businessman and 10% were housewife. 66.6% patients were having low socio-economic condition. C2 varicose veins were highly prevalent among the study population (35%) & lowest prevalence of C4b lipodermatosclerosis or atrophie blanche (11.7%) we have seen in the study. (31- 40) & (51-60) these two age group were more prone to have CVD, 28.33% (n51) & 26.67% (n48) (p <0.001*) respectively. Male were predominantly more prevalent to having CVD, 78.33% (n141), (p <0.001). Conclusion: Patients having CVD, invariably presented with the complains of heaviness of leg and unexplained leg swelling and Varicose vein were highly prevalent irrespective of sex. Advanced stages are more common in male patients. In every age group were having different stages of CVD. More awareness can help patients to get proper management and relief from chronic venous disease. Medicine Today 2023 Vol.35(2): 105-108","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139259856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Body Mass Index with Vitamin D and Parathormone (PTH) in Obese and Overweight Children, Study from a Tertiary Care Hospital of Bangladesh","authors":"K. J. Shyamaly, M. Karim, Baraka Badruddoza Tithi, Romana Akther, R. Parvin, Suraiya Begum","doi":"10.3329/medtoday.v35i1.64942","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64942","url":null,"abstract":"Introduction with aim and objectives: Childhood obesity and vitamin D deficiency both are emerging health issues. Vitamin D is essential for normal growth and development and frequently found low in obese and overweight children. The aim of this study was to assess serum vitamin D level, calcium, inorganic phosphate, alkaline phosphatase and parathormone (PTH) in obese and overweight children and to see the correlation between BMI, vitamin D and parathormone.\u0000Materials and Methods: This study was conducted at Pediatric Endocrinology clinic of department of Paediatrics of Bangabandhu Sheikh Mujib Medical University from the period of November 2016 to October 2018. We assessed 50 obese and overweight children for serum vitamin D, calcium, inorganic phosphate, alkaline phosphatase, and parathormone and we also tried to find out the correlations among the parameters in this cross sectional study.\u0000Results: Endocrine society clinical practice guideline was used to define vitamin D status. Result found that all of the obese/overweight children had low vitamin D (82% had deficiency and 18% had insufficiency). There was a statistically significant negative correlation between BMI and serum vitamin D level and positive correlation between BMI and the parathormone level (p value < 0.05). In this study significant negative association was found between vitamin D level and the PTH level p value <0.05.\u0000Conclusion: All the studied obese and overweight had vitamin D deficiency or insufficiency. There was negative correlation between BMI and serum vitamin D level and positive correlation between BMI and the parathormone level (PTH).\u0000Medicine Today 2023 Vol.35(1): 52-55","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74822808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern and Frequency of Microalbunuria with Different Types of Stroke","authors":"Z. Ahammed, Pijush Majumder, Rushmila Ferdous, Mohammad Mosharaf Hossen Talukder, A. Hoque","doi":"10.3329/medtoday.v35i1.64945","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64945","url":null,"abstract":"Introduction with aim and objectives: Cerebrovascular diseases have recently emerged as a major health problem affecting the elderly population. The spectrum includes some of the most common and devastating disorders like ischemic stroke, hemorrhagic stroke and anomalies in vascular system. Microalbuminuria is an early finding in urine in the patients of diabetes and hypertension and it is associated with macrovascular complications like cerebrovascular accident and myocardial infarction. The aim of this study was to find out the pattern and frequency of microalbunuria with different types of stroke.\u0000Materials and Methods: Fifty cases of stroke Patients admitted in CMCH medicine and neurology department from 1 January 2019 to 31 June 2019 were analyzed and urine for microalbumin was done. Univariate statistical analyses were performed to see the outcome in relation with blood volume by SPSS-19.\u0000Results: Regarding analysis of gender distribution of 50 study patients, 27(60%) were found male and 23(40%) were found female. Male to female ratio was 1:0.4. Among the 50 patients, different types of occupation were found. House wife was common occupation. Among the total patients, most of them were from lower middle class 24(61.4%). Others were from low 16(32.0%) and upper middle class 10(5.75%) group. Most of the patients were from rural residence 41(80%). In our study, 13(71.42%) patients had hypertension. Diabetes mellitus was found among 13(8.57%). Different examination findings were analyzed where mean GCS of ischaemic stroke was 14.5 and mean GCS of hemorrhagic stroke was 10.6, 12 patients had abnormal fundoscopic findings. Regarding analysis of serum LDL and serum Creatinine, mean LDL level was 123.95 and mean serum Creatinine level was 1.19. After analysis, mean of urine for Microalbumin of 30 Ischaemic stroke patients was 71.96mg/L and mean of urine for Microalbumin of 20 Hemorrhagic stroke patients was 80.70mg/L.\u0000Conclusions: We found high frequency of microalbuminuria in patients with stroke Therefore; microalbuminuria could be is a useful modifiable factor, in addition to conventional risk factors, in identifying those at increased risk of stroke.\u0000Medicine Today 2023 Vol.35(1): 63-66","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90898425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"C-reactive Protein Level in Bangladeshi Preeclamptic Patients and Its Comparison with Trimester-Matched Normal Pregnancy","authors":"Shahmima Siddiqua, S. Khatun, A. Saleh, Ishrat Jahan Karim, Rezwana Mirza","doi":"10.3329/medtoday.v35i1.64929","DOIUrl":"https://doi.org/10.3329/medtoday.v35i1.64929","url":null,"abstract":"Introduction with objective: Preeclampsia is a major cause of maternal and fetal morbidity and mortality in Bangladesh. This study aimed to estimate C-reactive protein (CRP) level among patients with preeclampsia and to compare with those of trimester-matched normal pregnancy.\u0000Materials and Methods: : This cross-sectional study was done from January 2005 to December 2006 at the different tertiary care hospital at Dhaka. A total of 33 preeclamptic and 33 normal pregnant women in the third trimester were enrolled in the study. The PE patients were divided into two groups: mild hypertension [diastolic blood pressure (DBP) <110 mm Hg] and severe hypertension (DBP _110 mm Hg). Similarly the patients were divided into two groups on the basis of proteinuria, group I ( 2+>=1gm/l) and group II (3+_3gm/l). Both PE and control groups were matched for their age and parity. Estimation of serum CRP was done by Turbulometry method.\u0000Results: CRP concentration (mg/l) was 4.55±2.83 in control group and 23.52±24.85 in PE group which was significantly higher than in control group. CRP level was significantly higher (p<0.001) in severe PE than in mild PE group. Significant difference was also seen between the groups subdivided on the basis of proteinuria (p<0.05). In the whole population CRP values showed significant positive correlation with systolic and diastolic blood pressure (p<0.001) and significant negative correlation with gestational age at delivery and birth weight (gestational age: p<0.05, birth weight: p<0.001).\u0000Conclusion: Maternal CRP concentration was higher in patients with preeclampsia and was correlated with disease severity.\u0000Medicine Today 2023 Vol.35(1): 1-6","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72834597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}