Medicina Clinica Practica最新文献

{"title":"Flourishing through continuous medical education: Empowering medical educators","authors":"Heather A. Billings , Juliana M. Kling , Devyani Lal , Jon T. Nordrum , Mira T. Keddis","doi":"10.1016/j.mcpsp.2024.100460","DOIUrl":"10.1016/j.mcpsp.2024.100460","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000351/pdfft?md5=b9fc8d288af598d4432696bf73091f5c&pid=1-s2.0-S2603924924000351-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141950141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous sarcoidosis","authors":"Jullio C. Salas-Alanís , Mauricio Salas-Garza , María G. Moreno-Treviño , Luis C. Mata-Meléndez , Raymundo Garza-Martínez , Gerardo Rivera-Silva","doi":"10.1016/j.mcpsp.2024.100455","DOIUrl":"10.1016/j.mcpsp.2024.100455","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000302/pdfft?md5=7ea391955c1a0171f8fdf974f78d4f23&pid=1-s2.0-S2603924924000302-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurofibromatosis tipo 1 en paciente puérpera","authors":"Sergia Daniela Rosales Castro , Olman Daniel Gradis Santos , Ana María Enríquez Martínez , Shirley Andino Moya","doi":"10.1016/j.mcpsp.2024.100454","DOIUrl":"10.1016/j.mcpsp.2024.100454","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000296/pdfft?md5=6e1ddb9714a19c56a3dc536f18d986c9&pid=1-s2.0-S2603924924000296-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiencia clínica con la combinación de cinarizina y dimenhidrinato en el tratamiento del vértigo de origen diverso en atención primaria: una serie de casos","authors":"David Martín-Enguix ,&nbsp;Amara Helena Aladel Ponce ,&nbsp;Sandra Albamonte Navarro ,&nbsp;José Miguel Álvarez Cabo ,&nbsp;José Miguel Fernández Rodríguez ,&nbsp;José Ignacio González Lillo ,&nbsp;Judith Norma Montoya Fernández del Campo ,&nbsp;Manuel Ruiz Cuetos","doi":"10.1016/j.mcpsp.2024.100457","DOIUrl":"10.1016/j.mcpsp.2024.100457","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Dizziness, including vertigo, imbalance, and presyncope, affects 15–20% of adults, increasing the risk of falls, especially in the elderly. The interaction between signals from the peripheral vestibular system, vestibular nuclei, and the central nervous system, modulated by neurotransmitters such as glutamate, acetylcholine, and glycine, along with histamine, adrenaline, and noradrenaline, is crucial for balance. Dizziness arises when vestibular information does not match other sources and can be associated with various neurological, psychiatric, respiratory, or infectious conditions. Current treatment is based on rest, particle replacement maneuvers and medications such as betahistine and sedatives, but the fixed combination of cinnarizine and dimenhydrinate has proven effective in clinical trials, effectively treating vertigo of various origins by acting on peripheral and central vestibular systems.</p></div><div><h3>Patients</h3><p>We present 7 clinical cases, in which we have used the same treatment with cinnarizine and dimenhydrate at fixed doses of 20/40 mg.</p></div><div><h3>Results</h3><p>The combination of cinnarizine and dimenhydrinate proved effective in managing a variety of vestibular disorders, including recurrent benign paroxysmal positional vertigo, vestibular migraine, Meniere's syndrome, and presbivestibulopathy. Patients experienced improvement in vestibular symptoms, such as dizziness, vertigo, and imbalance, proving to be a safe and effective drug, demonstrating in some cases the resolution of symptoms in patients previously treated with other therapies.</p></div><div><h3>Conclusion</h3><p>The versatility of the combination allows its use in the treatment of vertigo of various origins, making it a comprehensive and valuable option for situations where the precise diagnosis of the causes of vertigo is not clear.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000326/pdfft?md5=3a7a612e1cfcd3c3038e79318fd550ee&pid=1-s2.0-S2603924924000326-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing clonidine and dexmedetomidine effects in the treatment of opiate withdrawal syndrome in poisoned patients","authors":"Azadeh Memarian ,&nbsp;Mahdiye Abiyarghamsari ,&nbsp;Shahin Shadnia ,&nbsp;Babak Mostafazadeh ,&nbsp;Peyman Erfan Talab Evini ,&nbsp;Mahdiye Golestani Fard ,&nbsp;Mitra Rahimi","doi":"10.1016/j.mcpsp.2024.100458","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100458","url":null,"abstract":"<div><h3>Background</h3><p>While opiate withdrawal syndrome (OWS) typically resolves within a few weeks, the discomfort in the initial days after discontinuing opioid use is intense. In this study, we compared the effects of 2 drugs, clonidine and dexmedetomidine, for treating OWS in patients admitted to the Toxicology ICU at Loghman-e Hakim Hospital.</p></div><div><h3>Methods</h3><p>We collected patient information for individuals diagnosed with OWS in this clinical trial study. Fifty-two patients, matched based on the type of drug use (methadone, opiate, heroin), were included and divided into 2 groups. We compared the clinical effects of 2 drugs, dexmedetomidine and clonidine, on OWS symptoms using the Clinical Opiate Withdrawal Scale (COWS). The dexmedetomidine group received a dosage of 0.5 mcg/kg/h continuous IV infusion; not to exceed 24 h, while the clonidine group received 1.2 mg per day for 24 h. We completed the COWS standard checklist and compared the results after 0, 12, and 24 h.</p></div><div><h3>Results</h3><p>At Zero hours' patients who were administered dexmedetomidine had a significantly higher average COWS score of 0.684, compared to a score of 0.053 for patients who received clonidine (<em>p</em>-value<!--> <!-->=<!--> <!-->.000201). At the 12-h, the distinction between the 2 treatment groups was no longer statistically significant, as evidenced by a <em>p</em>-value of .162829 (dexmedetomidine: 0.105 vs. clonidine: 0.000).</p></div><div><h3>Conclusions</h3><p>The results suggest that dexmedetomidine is superior to clonidine in reducing withdrawal symptoms. The study found that both medications had a significant decrease in COWS scores over time, indicating their effectiveness in alleviating withdrawal symptoms as time passed.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000338/pdfft?md5=6f499a35c0bf5fa0b77610e3df49f399&pid=1-s2.0-S2603924924000338-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apocrine miliaria","authors":"Jullio C. Salas-Alanís ,&nbsp;Mauricio Salas-Garza ,&nbsp;María G. Moreno-Treviño ,&nbsp;Raymundo Garza-Martínez ,&nbsp;José G. Silva-Hernández ,&nbsp;Gerardo Rivera-Silva","doi":"10.1016/j.mcpsp.2024.100456","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100456","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000314/pdfft?md5=1607694fe5a168611b700a74ef8f9483&pid=1-s2.0-S2603924924000314-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melatonin treatment in patients with atypical facial pain: A randomized, double-blind, placebo-controlled clinical trial","authors":"Tahereh Nosratzehi","doi":"10.1016/j.mcpsp.2024.100430","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100430","url":null,"abstract":"<div><h3>Background</h3><p>The present study was carried out to evaluate the effect of melatonin and placebo in the patients with atypical facial pain (AFP).</p></div><div><h3>Method</h3><p>This double blind randomized controlled study was carried out on 30 patients who were suffering from AFP. During this period, patients were divided in 2 study and control groups. Then, they were treated with melatonin. Melatonin group used four 3-mg daily and placebo group received 4 placebo which were similar in size, shape, color with melatonin until the end of treatment, and then the severity of burning sensation was measured by physician. Sleep quality was measured using the visual analog scale using the Petersburg questionnaire.</p></div><div><h3>Result</h3><p>The results of the present study show that the use of melatonin and placebo in patients with AFP reduces sensation and improves their sleep quality, although it may not reduce it completely. In this study, severity of burning was 5.71<!--> <!-->±<!--> <!-->1.42 after treatment in the study group and 5.93<!--> <!-->±<!--> <!-->2.65 in the control group, which was not statistically significant (<em>p</em> <!-->=<!--> <!-->.46). The mean score of sleep before treatment was not significantly different between the study (9<!--> <!-->±<!--> <!-->1.23) and the control (8<!--> <!-->±<!--> <!-->1.56) groups. The mean score of sleep after treatment between the study group (8<!--> <!-->±<!--> <!-->1.45) and the control group (7<!--> <!-->±<!--> <!-->1.23) was not significantly different (<em>p</em> <!-->=<!--> <!-->.43).</p></div><div><h3>Conclusion</h3><p>According to the result of the study, melatonin was not superior placebo in treatment of AFP.</p></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000053/pdfft?md5=773be6dd66de6b979d5c724771dd0fe0&pid=1-s2.0-S2603924924000053-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium abscessus infection associated with mesotherapy injections","authors":"Julio C. Salas-Alanís ,&nbsp;Gerardo Rivera-Silva ,&nbsp;Mauricio Salas-Garza ,&nbsp;David I. Orozco-Pasadas ,&nbsp;Raymundo Garza-Martínez ,&nbsp;María G. Moreno-Treviño","doi":"10.1016/j.mcpsp.2024.100452","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100452","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000272/pdfft?md5=0bad6f64c60724a3f453a806de412f2e&pid=1-s2.0-S2603924924000272-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Keratoderma palmoplantaris varians","authors":"Gerardo Rivera-Silva ,&nbsp;Luis F.P. Blanco-Ortega ,&nbsp;María G. Moreno-Treviño ,&nbsp;Julio C. Salas-Alanís ,&nbsp;Ma. Guadalupe Treviño-Alanís ,&nbsp;José G. Silva-Hernández","doi":"10.1016/j.mcpsp.2024.100453","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100453","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000284/pdfft?md5=924cfc77df206cc1433f4858933822e2&pid=1-s2.0-S2603924924000284-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141438834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncommon complication of late perforation of the right atrium with active fixation atrial electrode","authors":"Lorenzo Socias Crespí ,&nbsp;Tomas Ripoll-Vera ,&nbsp;Francisco Trucco Espinosa","doi":"10.1016/j.mcpsp.2024.100450","DOIUrl":"https://doi.org/10.1016/j.mcpsp.2024.100450","url":null,"abstract":"","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2603924924000259/pdfft?md5=a43aac0dae34cae3f959a093bc75627c&pid=1-s2.0-S2603924924000259-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141434711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}