Mueen Al Abdullah, Esam Al Sharieda, Hasanain Al-Ali
{"title":"Etiological Factors of Hoarseness in Patients Attending Basrah General Hospital","authors":"Mueen Al Abdullah, Esam Al Sharieda, Hasanain Al-Ali","doi":"10.37319/iqnjm.5.2.3","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.3","url":null,"abstract":"Background: Hoarseness is a common symptom in otolaryngology practice, and it’s the earliest manifestation of a large variety of conditions directly or indirectly affecting the larynx, ranging from benign to most malignant. Aim: This study was undertaken to find out a clinical profile, the incidence of common predisposing and etiological factors of hoarseness. Methods: Two hundred cases of hoarseness for 18 months were studied. All cases were analyzed for detailed history and examination with visualization of the larynx through rigid video laryngoscopy or flexible nasopharyngolaryngoscopy and in some cases, direct laryngoscopy and biopsy were taken for histopathological study. The final results were analyzed by simple manual analysis with frequency and percentage using Microsoft Excel Software 2007. Results: A total of 200 patients were included in the study. Among them, patients in the age groups of 31–40 years and 41–50 years were the main sufferers of hoarseness. Similarly, among 200 patients 124 (62%) were males whereas 76 (38%) were females, with the male to female ratio of 1.6:1. Vocal cord nodules were the most commonly encountered etiology with a frequency of 17.5 % whereas tuberculous laryngitis was the least commonly encountered etiology with a frequency of 0.5%. Conclusions: There was an etiological variation in hoarseness ranging from simple laryngitis to the most life-threatening malignancies. It is important not to ignore the hoarseness and precise history, examination and investigations should be done to diagnose the early underlying pathological changes for prevention and accurate management.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125732580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation and Characterization of L-ascorbic Acid Ethosomal Formulation for Enhancement of Permeation","authors":"Ahmed Alabada, Murtadaa Mohammed","doi":"10.37319/iqnjm.5.2.4","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.4","url":null,"abstract":"Background: Vesicular system is a good approach to improve hydrophilic drug permeability using phospholipids as Nanocarriers to increase lipophilicity and reduce vesicle size. L-ascorbic acid is a water soluble vitamin with antioxidant activity with poor skin permeability. Aim: The purpose of this work is to prepare LAA-containing ethosomes formulations utilizing a modified thin film hydration approach. Methods: eight formulas were prepared using different types of phospholipids (egg yolk lecithin and soya lecithin), different volumes of ethanol (2 and 3mL), and tween 80 as a surfactant. The prepared formulas (F1, F2, F3, F4, F5, F6, F7 and F8) were characterized to detect the best one regarding the physical appearance, pH, average vesicle size, polydispersity index (PDI) and entrapment efficiency. Scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to evaluate the morphological properties Results: The best prepared ethosomal formula was F3 which contains (1.5g) LAA, (0.1 g) egg yolk lecithin, (2 mL) ethanol, 0.025 mL tween 80 and (q.s.10mL) of distilled water. Its average vesicle size value (176nm), PDI = 0.243, high entrapment efficiency (89.8%) and good physical stability. The morphological properties showing spherical, smooth, and devoid of drug crystalline structures. The drug-excipient compatibility is confirmed using (FTIR, DSC and PXRD) analyses. Additionally, the Ex-vivo drug permeation investigation demonstrated that the prepared formula of LAA had flux and permeability coefficients that were two times higher than the control. Conclusions: The average vesicle size and PDI are affected by, the volume of ethanol, type of lecithin and presence of solubilizing agent.\u0000 ","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132701381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of Placental Weight with Neonatal Weight and HbA1c in Normal Sudanese Pregnant Ladies in Alban-Jaded Teaching Hospital","authors":"Ibrahim Ali, A. Osman, W. Ahmed","doi":"10.37319/iqnjm.5.2.6","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.6","url":null,"abstract":"Background: The placenta is a life-supporting organ for the growing fetus. Several studies have highlighted the relationship between placental weight and neonatal birth weight; however, the role of glycosylated hemoglobin (HbA1c) has not been addressed. Aim: The study aimed to determine the relationship between the placental weight, neonatal birth weight, and HbA1c at term pregnancy in a Sudanese hospital. Methods: This was a cross-sectional hospital-based study conducted at Al Ban-Jaded Hospital between November and December 2022. Data, including the gestational age at delivery (in weeks), parity, mode of delivery, fetal birth weight, placental weight, fetal gender, and presence or absence of maternal medical diseases, was obtained from 60 singleton term deliveries who met the inclusion criteria for the study. The tested data was analyzed using SPSS version 25, and t-test was used to compare the statistical significance (P value ≤ 0.05 was considered statistically significant). Results: The mean age was 27.02 ± 6.8 years. The mean HbA1C was 5.98% ± 0.39% (5.2%–6.9%). Glycated hemoglobin was elevated (≥5.7%) in the majority (46, 76.7%) of pregnancies. The mean placental weight was 290 ± 106 g (100 g–700 g), while the mean birth weight was 3.00 kg ± 0.36 kg (2.3 kg–3.8 kg), and the placental/birth weight ratio was 9.6%. There was a significant positive correlation between neonatal weight and placental weight (r=0.514, P value=0.000). Also, neonatal weight and placental weight had a significant positive correlation with HbA1C (r=0.657, P value=0.000). Placental weight and neonatal birth weight significantly increased with the gestational age of neonates (P value <0.05), with a slight drop noted in term gestation. Conclusions: There is a positive correlation between placental weight and birth weight of the neonate in pregnancies with high maternal HbA1C, and placental weight and birth weight were higher than in pregnancies with normal maternal HbA1C.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"222 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122400416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hasanain Al-Ali, J. Al-Asadi, Abdulrazzaq Alrubaye, H. Ali
{"title":"Ototoxicity in Cancer Patients on Cisplatin Therapy Attending Basrah Oncology Centre: A Cohort Study","authors":"Hasanain Al-Ali, J. Al-Asadi, Abdulrazzaq Alrubaye, H. Ali","doi":"10.37319/iqnjm.5.2.2","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.2","url":null,"abstract":" \u0000Background: Cisplatin is a chemotherapeutic agent that is used extensively for the treatment of a broad spectrum of tumors. However, progressive irreversible side effects of Cisplatin, including ototoxicity, have been reported. Methods: A cohort study was implemented from 1 April to 30 August 2015 to study the association between Cisplatin chemotherapy and sensory-neural hearing loss as the major and most important sign of ototoxicity. The cohort group included cancer patients treated with Cisplatin, while patients on Carboplatin were the control group. Cisplatin and Carboplatin belong to alkylating platinum chemotherapy drugs, which are used to treat various malignant solid tumors. Data collection was done through a questionnaire, including information related to sociodemographic characteristics and current and past medical history. Hearing loss was assessed using pure tone audiometry at the time of starting chemotherapy and one month later. Results: The total number of patients was 50, with male to female ratio 1:1 and a mean age of 49.7±14.7 (range 18–80 years): 27 patients were on Cisplatin with a mean age of 50.3±13.5 and 23 patients were on Carboplatin chemotherapy with a mean age of 51.9±15.1 with no significant difference in age (P=0.695). A highly significant association between Cisplatin use and sensory-neural hearing loss (RR, 5.13; P <0.001) was noted. No significant association was found between hearing loss and sociodemographic characteristics or other clinical conditions. Conclusions: Ototoxicity represents a significant clinical sequel of Cisplatin chemotherapy in patients with cancer. A future study using a larger sample size aiming at the evaluation and prevention of Cisplatin induced ototoxicity is recommended.\u0000 ","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127202912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiba Adnan Hameed, Mohammad Yahya Abdulrazaq, Abass Farhood Hussein
{"title":"Tuberculosis as a Complication of BCG in the Treatment of Bladder Carcinoma","authors":"Hiba Adnan Hameed, Mohammad Yahya Abdulrazaq, Abass Farhood Hussein","doi":"10.37319/iqnjm.5.2.1","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.1","url":null,"abstract":"Bacillus Calmette-Guérin (BCG), is a live attenuated strain of Mycobacterium bovis, and is the essential constituent of the vaccine against tuberculosis (TB) and adjuvant treatment for bladder cancer. This vaccine has a potential pathogenic action; bacilli can cause recorded complications that can be located locally near the site of inoculation and at a distance through blood dissemination root. The BCG-related disease can represent a side effect of anti-TB vaccination in patients with acquired or congenital immunodeficiency or a complication of the therapeutic oncologic schedule in patients with malignancy. Here in we report three cases of BCG-related disease which visited our national tuberculosis Iraqi center in 2022, two of those with locally developed TB and the third presented with disseminated miliary TB.\u0000 ","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131519034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ZiyadT Shwaish, Mahmood Alatbee, W. H. Al-Kawaz, Nada Hasan Al-Kawaz
{"title":"Prevalence of Overweight and Obesity Among Students of Intermediate Schools in Basra","authors":"ZiyadT Shwaish, Mahmood Alatbee, W. H. Al-Kawaz, Nada Hasan Al-Kawaz","doi":"10.37319/iqnjm.5.2.5","DOIUrl":"https://doi.org/10.37319/iqnjm.5.2.5","url":null,"abstract":"Background: Obesity is one of the most serious public health challenges of the 21st century and represents a serious health problem for low- and middle-income countries, particularly in urban settings. Its prevalence has increased at an alarming rate. Globally, more than 340 million children and adolescents aged 5–19 years are overweight or obese, and approximately two-third of them live in developing countries. Aim: The present study was implemented to assess the prevalence rates of overweight and obesity among adolescents in intermediate schools in Basrah, Iraq. Methods: A cross-sectional study was conducted during the second semester (between January 15 and May 30, 2013) among children attending public and private secondary schools in Basra city to determine the relationship between certain variables and the prevalence of overweight and obesity. Results: According to the study findings, the overall prevalence rates of overweight and obesity among adolescents aged 13–15 years in intermediate schools were 20.6% and 22.6%, respectively. Conclusions: A combination of decreased physical activity, sedentary behaviors (watching TV, playing video games, and using the internet), ingestion of unhealthy foods, and consumption of soft drinks may be responsible for the observed increased prevalence of overweight and obesity among adolescent students in Basra city.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126029051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Smell Disorders And Covid 19 Pandemic: Across sectional study","authors":"","doi":"10.37319/iqnjm.4.2.8","DOIUrl":"https://doi.org/10.37319/iqnjm.4.2.8","url":null,"abstract":"Background: Since its emergence in December 2019, SARS-CoV2 infection has been characterized by several signs and symptoms related to the respiratory and other body systems. One of the important symptoms of this infection includes smell disorders that result in the reduction, complete loss, or alteration in smell perception. Although several studies have investigated these disorders from various perspectives, these disorders require further elucidation. Objective: The objective of this study was to analyze the data pertaining to COVID-19 infected individuals who suffered from smell disorders, and to identify the correlation between different variables. Materials and Methods: A total of 310 individuals from 5 countries participated in the web-based electronic questionnaire conducted from June 15 to July 15, 2021. Data were collated and analyzed using the IBM SPSS (v. 23) software. Results: Out of the 310 participants, 228 individuals (73.5%) exhibited a history of COVID-19 infection, with 151 males (66.2%) and 77 females (33.8%). The most common age-group infected by SARS-CoV2 was 41–60 years (44.2%), and 168 patients (73.7%) exhibited smell disorders during infection, with the most common disorder being complete loss of smell. Furthermore, 45.2% patients reported reduced or alterations in smell perception (hyposmia and dysosmia, respectively), while 87.5% patients recovered completely, with most patients recovering within 1–3 weeks. More than one-third of the patients with smell disorders undertook olfactory training at home, and more than half of them benefitted from the training. Moreover, 45.7% of the patients with smell disorders experienced some form of depression during or after the infection. However, no correlation was observed between patients with allergic rhinitis and COVID-19 infection. Conclusion: Different types of smell disorders were common in individuals infected with COVID-19. Nonetheless, most patients recovered completely and spontaneously. While olfactory training may have benefitted in recovery, few patients suffered from depression and required early psychological intervention to overcome the COVID-19 sequelae. Background: Since its emergence in December 2019, SARS-CoV2 infection has been characterized by several signs and symptoms related to the respiratory and other body systems. One of the important symptoms of this infection includes smell disorders that result in the reduction, complete loss, or alteration in smell perception. Although several studies have investigated these disorders from various perspectives, these disorders require further elucidation. Objective: The objective of this study was to analyze the data pertaining to COVID-19 infected individuals who suffered from smell disorders, and to identify the correlation between different variables. Materials and Methods: A total of 310 individuals from 5 countries participated in the web-based electronic questionnaire conducted from June 15 to July 15, 2021. Data","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116062059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Resistance Exercise Therapy on Patients' Physiological Status during Hemodialysis: A Randomized Controlled Trial","authors":"Ahmed Lateef Alkhaqani","doi":"10.37319/iqnjm.4.2.3","DOIUrl":"https://doi.org/10.37319/iqnjm.4.2.3","url":null,"abstract":"Background: Management disorder of vital signs remains a critical issue worldwide, particularly regarding hypertension in chronic renal disease (CRD), both of which are associated with a higher risk of cardiovascular (CV) and renal events. Physical inactivity resulting in poor exercise capacity is a common consequence of chronic kidney disease and is associated with increased mortality in the general population. Nursing management for patients undergoing hemodialysis requires an experienced nurse who understands the types of complications. Objective: The present study aimed to evaluate the effectiveness of resistance exercise therapy on patients’ physiological status by utilizing a checklist of physiological parameters and comparing it with a control group. Patients and Methods: The study was designed as a randomized controlled trial (RCT), using a double-blind technique, and it was conducted on patients divided into two groups (study and control groups). A total of 63 patients were included as follows: 32 patients for the study group and 31 patients in the control group. The patients were diagnosed with chronic kidney disease and were undergoing hemodialysis. The patients were randomly assigned to receive exercise therapy under the supervision of trained therapists during the second hour of the three routine hemodialysis treatments per week and under the supervision of the researcher. The study took place in Al-Najaf Al-Ashraf City/Al-Sadder Medical City and Al-Hakeem Hemodialysis Center. Results: The study results indicated an improvement in the physiological status of the study group compared to the control group. Conclusions: Exercise therapy effectively improves the physiological status of patients with chronic kidney disease undergoing hemodialysis.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115016822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hydatidiform mole; histological types and age distribution in Basrah","authors":"Wafa Ali, Rasha S. Manuel, Jasim M. A. Al-Diab","doi":"10.37319/iqnjm.4.2.1","DOIUrl":"https://doi.org/10.37319/iqnjm.4.2.1","url":null,"abstract":"Background Hydatidiform mole (HM) is a placental pathology, which is a form of gestational trophoblastic disease (GTD). HM is classified into complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM). The incidence of molar pregnancy varies according to the geographical area. It is found to be higher in developing countries. Age is a risk factor for developing HM. In this study, we aim to determine the frequency of hydatidiform mole among cases of early trimester evacuation specimens and its relation to patient's age at Basrah maternity and paediatric hospital and Al- Mosawi private hospital. Method This was a descriptive retrospective study for a four-year period; all cases of early trimester evacuation specimens were from January 1, 2017, to December 31, 2020. All specimens were fixed in 10% formalin and dehydrated in graduated alcohol, (5) micron thickness sections were obtained, stained with hematoxylin and eosin and examined, and cases of CHM, PHM and RPOG were analyzed. Result A total of 216 evacuation specimens were examined, and the patients age ranged from 14–50 years. Among these, 78.2% of patients were between 20 and 30 years. The percentage of RPOC was 54.2%, while that of CHM was 19.4% and that of PHM was 26.4%. The maximum cases of complete and partial mole were in the 20–30 years age group. Conclusion The frequency of HM was high compared to many other studies.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122892603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empiric guideline therapy for simple UTI at outpatient clinics: a prospective observational study.","authors":"K. Jawad","doi":"10.37319/iqnjm.4.2.7","DOIUrl":"https://doi.org/10.37319/iqnjm.4.2.7","url":null,"abstract":"Background: Community-acquired urinary tract infection is a widespread problem encountered in the outpatient clinics of most hospitals. UTI has various clinical presentations; some are simple UTIs that can be managed with outpatient antibiotics. The current treatment of UTI is empirical, based on the limited and predictable spectrum of etiological microorganisms. Objectives: To collect information on the susceptibility tests of microorganisms in simple urinary tract infections (UTIs) and outline the best empiric antimicrobial prescribed for them. Methods: A total of 117 patients from 14 to 70 years of age (mean age = 43.61years, standard deviation = + 24.5) received the care of our surgical and urological outpatient clinics in Alnuman Teaching Hospital, Baghdad, Iraq, between March 1, 2019, and September 1, 2020. The patients who were showing symptoms of simple uncomplicated UTI and were prescribed empiric antibacterial treatment and requested for a sample of midstream urine for culture and sensitivity tests were enrolled in this prospective study. The susceptibility test for (ciprofloxacin, trimethoprim, gentamycin, and ceftriaxone) was performed using the Kirby–Bauer disc diffusion method. The data were input into SPSS 22.0 for statistical analysis. Pearson’s chi-squared test was used to compare parameters. The data have been presented as the number of variables (n) and percentages (%). Statistical significance was set at P < 0.05. Results: The frequencies of isolated uropathogens were as follows: E. coli, n = 65 (77.4%); Klebsiella spp., n = 9 (10.7%), Proteus spp., n = 3 (3.57%), Enterobacter spp., n = 3 (3.57%)., Staphylococcus spp., n = 2 (2.38%)., Pseudomonas spp., n = 1 (1.19%), and Candida spp., n = 1 (1.19%). The resistance rates of the most prevalent microorganisms were E. coli isolates to trimethoprim, ciprofloxacin, gentamycin, and ceftriaxone. The lower resistance rates to ceftriaxone in E. coli isolates (29.7%) was not clinically significant, with p < 0.05. Gentamycin showed significant sensitivity and resistance rates of 58.3% and 33.3% respectively, among the antimicrobials used (p < 0.05). The clinical effectiveness of empirical antimicrobial use in the treatment of simple UTIs showed no statistically significant correlation with P < 0.05. Conclusions: Trimethoprim and ciprofloxacin should not be used in empirical therapy for UTIs because of their increased resistance rates. A review of the local guidelines should be considered.","PeriodicalId":333401,"journal":{"name":"Iraqi National journal of Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125240292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}