Shanghai International Conference on Laser Medicine and Surgery最新文献_第4页

Experimental and clinical studies on transmyocardial laser revascularzation (TMLR) 经心肌激光血管重建术(TMLR)的实验与临床研究

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639109

M. Okada

{"title":"Experimental and clinical studies on transmyocardial laser revascularzation (TMLR)","authors":"M. Okada","doi":"10.1117/12.639109","DOIUrl":"https://doi.org/10.1117/12.639109","url":null,"abstract":"The number of patients with coronary artery disease has been increasing in Japan and several kinds of treatments have been performed to reduce their cardiovascular diseases. In patients with small branches, or diffuse stenotic lesions of the coronary arteries, on whom coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) cannot be carried out, it has been hemodynamically demonstrated possible to supply arterial blood from the left ventricular cavity to the ischemic myocardium through laser channels. On the basis of excellent experimental studies using mongrel dogs, newly created laser channels 0.2 mm in diameter have been confirmed to be histologically patent even 3 years after transmyocardial revascularization(TMLR). Thus, this method could be applied as an alternative procedure of transmyocardial revascularization. First clinical procedure of TMLR alone was performed on 55 year-old male patient with severe angina pectoris who had undergone pericardiectomy 7 years ago. He had no candidate for percutaneous coronary intervention, or coronary artery bypass grafting, because his left venticle had severe adhesion to the left lung. Therefore, this method was finally carried out. He is getting well after this surgical intervention. This procedure should be recommended for the patient with end-stage coronary artery disease.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132404056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early panretinal photocoagulation for the treatment of ischemic central retinal vein occlusion 早期全视网膜光凝治疗缺血性视网膜中央静脉闭塞

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639341

Zikui Yu, N. He

引用次数: 0

Research of epidermal cellular vegetal cycle of intravascular low level laser irradiation in treatment of psoriasis 低水平激光血管内照射治疗银屑病表皮细胞植物周期的研究

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639327

Jing Zhu, Xiaoqing Bao, Meijue Zhang

引用次数: 0

Development of a handy-type laser surgical unit 便携式激光手术装置的研制

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639157

Y. Abe, K. Wakamatsu, Shigeru Goto

{"title":"Development of a handy-type laser surgical unit","authors":"Y. Abe, K. Wakamatsu, Shigeru Goto","doi":"10.1117/12.639157","DOIUrl":"https://doi.org/10.1117/12.639157","url":null,"abstract":"We proposed a concept of a handy-type laser surgical unit for use in outpatient, in ward and in open-air field. To investigate the possibility of the concept, a handy-type semiconductor laser surgical unit was developed experimentally using 2-watts power laser diode with no built-in electrical cooling unit (Peltier chip) and a small rechargeable battery. The drive circuit was constructed with only current limit and ACC circuits. The laser diode was cooled with heat sink and simple fan. Laser irradiation was set to stop at 30 degree Celsius by monitoring the temperature of laser diode with thermistor temperature sensor. With this system, 1.18 watts of laser power at the end of optical fiber with both 600 and 900μm core diameter, and about 30 minutes of continuous irradiating time with Ni-Cd battery (4.8V 1,500mA/h) could be obtained with no over heating in laser diode. The result showed that the high power semiconductor laser could be driven with small battery when specially designed. In an animal experiment, small bleeding could be managed with contact irradiation method. This kind of simple laser surgical unit is considered to be useful for the management of small bleedings in clinical.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126629353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of the technique in treatment of internal hemorrhoids with Nd:YAG laser Nd:YAG激光治疗内痔技术的改进

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639385

Xiaoqing Bao, Jing Zhu, Hongmin Shi

引用次数: 0

Influence of intravascular low level He-Ne laser irradiation on iNOS, total-NOS, and ET-1 in acute spinal cord-injured rabbits 血管内低水平He-Ne激光照射对急性脊髓损伤家兔iNOS、总nos和ET-1的影响

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639315

Zhenchun Yin, Yinghai Dong, Jing Zhu

{"title":"Influence of intravascular low level He-Ne laser irradiation on iNOS, total-NOS, and ET-1 in acute spinal cord-injured rabbits","authors":"Zhenchun Yin, Yinghai Dong, Jing Zhu","doi":"10.1117/12.639315","DOIUrl":"https://doi.org/10.1117/12.639315","url":null,"abstract":"Objective To research the influence of intravascular low level Laser irradiation (ILLLI) on total NOS, iNOS, and ET-1 in spinal cord following acute spinal cord injury (ASCI), and discuss the protective effects of ILLLI on neurons. Methods 72 rabbits were randomly divided into 3 groups: treatment group, injury group and control group. In treatment group and injury group, after laminectomy at the level of T-13, ASCI was performed by using Allen's method with slight modification (6g×10cm) on rabbits. After injury, rabbits were treated immediately with He-Ne laser (power 5 mW, 1 hour per day for 10 days). At the day of 10th after treatment, total-NOS, iNOS, and ET-1 in spinal cord tissues were measured. Results The expression level of total-NOS, iNOS, and ET-1 in spinal cord in injury group were significantly higher than those in control group (P<0.05), while after ILLLI the level of these index in treatment group decreased statistically significantly compared with those in injury group (P<0.05). Conclusion ILLLI can significantly decrease the expression level of total-NOS, iNOS, and ET-1 in spinal cord. It indicates that ILLLI can relieve the overexpression of total-NOS, iNOS, and ET-1, and thus can perform protective effects on neurons in the course of secondary spinal cord injury (SSCI) following ASCI","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126873668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Model for monitoring the process of photodynamic therapy in patients 监测患者光动力治疗过程的模型

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639221

Takato O. Yoshida, E. Kohno, T. Sakurai, T. Hirano, Seiji Yamamoto, S. Terakawa

{"title":"Model for monitoring the process of photodynamic therapy in patients","authors":"Takato O. Yoshida, E. Kohno, T. Sakurai, T. Hirano, Seiji Yamamoto, S. Terakawa","doi":"10.1117/12.639221","DOIUrl":"https://doi.org/10.1117/12.639221","url":null,"abstract":"The photodynamic therapy (PDT) on tumors is quite effective and widely applied but usually carried out without an immediate evaluation of results. We measured the tumor fluorescence in mice with a fiber probe connected to a linear array spectral analyzer (PMA-11, Hamamatsu Photonics). The spectrum showed a transient change in fluorescence color from red to green during Photofrin-mediated PDT. In order to examine the source of green fluorescence, the mitochondria were accessed under a Nipkow disk-scanning confocal microscope in the HeLa cell in culture after labeling them with a red fluorescent protein (DsRed1-mito) and staining the cell with Photofrin (Axcan Scandipharm). Changes in fluorescence color from red to green were observed in the area of mitochondria upon their swelling during irradiation. This finding in vitro provided clear evidence that the change in fluorescence color from red to green observed in vivo was due to the mitochondrial destruction associated with the cell-death by PDT. This technique of spectral monitoring in tumor may be useful for detection of the cell-death signal during PDT in patients.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134437116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of intravascular irradiation of He-Ne laser on cerebral infarction: hemorrheology and apoptosis He-Ne激光血管内照射对脑梗死的影响:血液流变学和细胞凋亡

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639329

Jian Zhu, M. Liang, H. Cao, Xiaoyuan Li, Shaochen Li, Shun-hao Li, Wen-qi Li, Jin-hong Zhang, Lei Liu, Jian-hong Lai

{"title":"Effect of intravascular irradiation of He-Ne laser on cerebral infarction: hemorrheology and apoptosis","authors":"Jian Zhu, M. Liang, H. Cao, Xiaoyuan Li, Shaochen Li, Shun-hao Li, Wen-qi Li, Jin-hong Zhang, Lei Liu, Jian-hong Lai","doi":"10.1117/12.639329","DOIUrl":"https://doi.org/10.1117/12.639329","url":null,"abstract":"Objective: To explore the efficacy of He-Ne laser intravascular irradiation on infarction and hemorrheology. To observe the effects of intravascular low level He-Ne laser irradiation (ILLLI) of blood on cell proliferation, apoptosis and chromosome in lymphocyte from cerebral infarction. Methods: Seventy cases with cerebral infarction were randomly divided into groups control group (35 cases) treated only with common drugs and therapeutic group (35 cases) treated besides common drugs also by He-Ne laser intravascular irradiation. Their hemorrheology index and treatment results were observed and compared. The blood lymphocytes of cerebral infarction were cultured before and after treatment. After that, the mitosis index (MI), cell kinetics index (CKI), sister-chromatid exchanges (SCE) frequencies and apoptosis were determined. Results: The therapeutic group was better than the control one. The effective rate in the therapeutic group was 88.6%, in the control one was 65.7%. The viscosity and fibrinogen, etc. were better than that in the control group with significant difference (P<0.01). The lymphocyte proliferation index was significantly two increased than the control one (P>0.05) in cerebral infarction patients after treatment; The CKI of lymphocytes had no obvious difference among groups (P>0.05); SCE frequencies of lymphocytes had no statistic significance between control group and ILLLI on (P>0.05). It showed the apoptosis rate of lymphocytes in cerebral infarction patients after ILLLI treatment increased significantly compared with the control group, (P<0.001). There was a significant difference of apoptosis rate of lymphocytes in cerebral infarction patients than the control (P<0.001). Conclusions: During the He-Ne laser intravascular irradiation of the cerebral infarction, the low level He-Ne by ILLLI can increase the proliferation of lymphocytes, and can induce lymphocytes to apoptosis, but has no mutagenicity of cells.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124866401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Ureteropyeloscopy and holmium:YAG laser lithotripsy for treatment of ureteral calculi: report of 356 cases 输尿管镜联合钬激光碎石治疗输尿管结石356例报告

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639376

Zhong Wu, Qiang Din, Haowen Jiang, Jing-cun Zen, Jiang Yu, Yuan-fan Zhang

{"title":"Ureteropyeloscopy and holmium:YAG laser lithotripsy for treatment of ureteral calculi: report of 356 cases","authors":"Zhong Wu, Qiang Din, Haowen Jiang, Jing-cun Zen, Jiang Yu, Yuan-fan Zhang","doi":"10.1117/12.639376","DOIUrl":"https://doi.org/10.1117/12.639376","url":null,"abstract":"Objective: To evaluate the efficacy and safety of holmium:YAG laser lithotripsy for the treatment of ureteral calculi. Methods: A total of 356 patients underwent ureteropyeloscopic lithotripsy using holmium:YAG laser with a semirigid uretesopyeloscope, 93 upper, 135 middle, and 128 lower ureteral stones were treated. Results: The overall successful fragmentation rate for all ureteral stones in a single session achieved 98% (349/356). The successful fragmentation rate stratified by stone location was 95% (88/93) in the upper ureter, 99% (134/135) in the mid ureter , and 99% (127/128) in the distal ureter. 12 cases with bilateral ureteral stones which caused acute renal failure and anuria were treated rapidly and effectively by the holmium:YAG laser lithotripsy. No complications such as perforation and severe trauma were encountered during the operations. 2weeks~17months (with an average of 6.8 month) follow up postoperatively revealed that the overall stone-free rate was 98% (343/349) and no ureteral stenosis was found. Conclusions: Holmium:YAG laser lithotripsy is a highly effective, minimally invasive and safe therapy for ureteral calculi. It is indicated as a first choice of treatment for patients with ureteral calculi, especially for the ones with mid-lower levels of ureteral calculi.","PeriodicalId":325950,"journal":{"name":"Shanghai International Conference on Laser Medicine and Surgery","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126410834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Determination of the ablation threshold of 1341nm Nd:YAP laser radiation in the larynx of rabbit 1341nm Nd:YAP激光对家兔喉部消融阈值的测定

Shanghai International Conference on Laser Medicine and Surgery Pub Date : 2005-07-25 DOI: 10.1117/12.639161

Huiyun Lin, S. Xie, Buhong Li

引用次数: 0