PCJN Pharmaceutical and Clinical Journal of Nusantara最新文献

Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method 番荔枝鲜果仁、鲜纱丽和鲜乙醇提取物的抗氧化活性研究叶片采用DPPH法

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2023-03-24 DOI: 10.58549/pcjn.v2i01.60

Eva Fransiska, A. Daulay, Ridwanto Ridwanto, Rafita Yuniarti

{"title":"Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method","authors":"Eva Fransiska, A. Daulay, Ridwanto Ridwanto, Rafita Yuniarti","doi":"10.58549/pcjn.v2i01.60","DOIUrl":"https://doi.org/10.58549/pcjn.v2i01.60","url":null,"abstract":"Antioxidants are compounds that are able to ward off or reduce free radicals in the body so that they can prevent several diseases. Soursop leaves (Annona muricata L.) are used as a traditional herbal medicine to prevent or treat cancer, as well as a natural antioxidant, which is usually used by people by boiling it. The purpose of this study was to look at the phytochemical screening by comparing fresh boiled water, fresh juice, and a fresh extract of soursop leaves, as well as test the antioxidant activity with the addition of DPPH (1,1-diphenyl-2-picrylhydrazyl) and measured using a UV-Vis spectrophotometer at 516 nm. The results of the soursop leaf phytochemical screening showed that there were groups of chemical compounds such as flavonoids, glycosides, tannins, and saponins. The results of testing the antioxidant activity by looking at the maximum wavelength of DPPH, using a UV-Vis spectrophotometer, obtained IC50 values for fresh juice of 770.067 µg/mL, fresh decoction of 1,022.8422 µg/mL, and ethanol extract of 299.733 µg/mL. Based on the results of the study, it was shown that the ethanol extract had stronger antioxidant activity than a fresh decoction and the fresh juice of soursop leaves.","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125957627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Level of Public Knowledge About the Treatment of Gastritis at The Kyan Sehat Pharmacy Kyan Sehat药房治疗胃炎的公众知识水平

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2023-03-24 DOI: 10.58549/pcjn.v2i01.59

Dian Sarirotul Karimah, Jamaludin Al Jamaludin Efendi

{"title":"The Level of Public Knowledge About the Treatment of Gastritis at The Kyan Sehat Pharmacy","authors":"Dian Sarirotul Karimah, Jamaludin Al Jamaludin Efendi","doi":"10.58549/pcjn.v2i01.59","DOIUrl":"https://doi.org/10.58549/pcjn.v2i01.59","url":null,"abstract":"Gastritis is an inflammatory condition of the gastric mucosa, which can be acute or chronic, with a very high number of sufferers in Indonesia. Public knowledge and awareness about gastritis is still lacking, one of which is the adoption of an unhealthy lifestyle. If left continuously, it will damage the function of the stomach and will increase the risk of getting gastric cancer which can lead to death. This research was able to find out “Level of Public Knowledge About Gastritis Treatment at the Kyan Sehat Pharmacy”. This type of research is observational by making descriptive observations, The data taken is done quantitatively. The data collected is in the form of quantitative data. This study describes how the level of public knowledge about the treatment of gastritis, explore the relationship between the level of knowledge and self-medication behavior using a survey method with a questionnaire as the main instrument. The results show that the level of knowledge of the respondents regarding the treatment of gastritis is 55% which is a good category, the sufficient category is 40% and the less category is 5%. And gastritis treatment behavior obtained data as much as 17% have gastritis (ulcer) treatment behavior which is in the good category, for the sufficient category, namely 70%, and the less category, namely 13%. So knowledge about gastritis (ulcer) treatment has good knowledge, namely as much as 55% and gastritis (ulcer) treatment behavior has sufficient behavior as much as 70%","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"173 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124251528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Familiar Edible Flowers in Indonesia 印度尼西亚常见的食用花

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-30 DOI: 10.58549/pcjn.v1i01.7

I Nyoman Bagus Aji Kresnapati, Muhammad Eka Putra Ramandha, Nurul Indriani

引用次数: 0

Testing Honey on Chicken Embryos as Candidates for Herbal Medicine in Indonesia 在印度尼西亚对鸡胚胎进行蜂蜜作为草药候选药物的试验

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-26 DOI: 10.58549/pcjn.v1i01.6

M. Mafruchati, J. Makuwira

{"title":"Testing Honey on Chicken Embryos as Candidates for Herbal Medicine in Indonesia","authors":"M. Mafruchati, J. Makuwira","doi":"10.58549/pcjn.v1i01.6","DOIUrl":"https://doi.org/10.58549/pcjn.v1i01.6","url":null,"abstract":"The nutrients in honey had function as antioxidants. The aim of this study was to testing honey on chicken embryos as candidates for herbal medicine in Indonesia. This study used treatment method, consisting of 6 (six) doses of honey products. The solution volume of each treatment dose was fixed at 10 l/egg via the route to the air bag. At the age of 13 days, embryo morphology and possible abnormalities were observed in all treatments. Each two eggs are cracked. The remainder was continued by incubation in the incubator until day 21. During this time the eggs were observed and the number was recorded to find out which eggs would die and which eggs would hatch at the end of the incubation period. Newborn chicks (DOC) were weighed and observed for possible morphological abnormalities. From the results of the research conducted, it was found that the percentage of viable chicken eggs sprouted after being injected with honey (days 13-21 after inoculation) and the morphology of chicken embryos after being injected with honey. Chicken Embryo Weight and Body Length Measurements were carried out in chicken embryos. The conclusion of the study is that propolis from honey products can be used as herbal medicine.","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"297 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121268040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Apis Mellifera Propolis Extract As A Stimulator Of Brain Cell Development (Study On Experimental Animals) 蜜蜂蜂胶提取物促进脑细胞发育的实验动物研究

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-24 DOI: 10.58549/pcjn.v1i01.5

M. Mafruchati, J. Makuwira

{"title":"Apis Mellifera Propolis Extract As A Stimulator Of Brain Cell Development (Study On Experimental Animals)","authors":"M. Mafruchati, J. Makuwira","doi":"10.58549/pcjn.v1i01.5","DOIUrl":"https://doi.org/10.58549/pcjn.v1i01.5","url":null,"abstract":"Apis mellifera could have potential as cell growth stimulator ability of the propolis. It also expected to increase the growth and proliferation of brain cells. This study aimed to analyze Apis mellifera Propolis Extract as a Stimulator of Brain Cell Development in Experimental Animals. This research is an experimental study using a completely randomized design (CRD) with 6 treatments and 4 replications. The research consisted of making Propolis Extract, Making Media (DMEM Stock Media, Washing Media, Culture and Treatment Media), Brain Cell Isolation and Culture, Observation of Culture Results (Cell Viability, Population Doubling Time, The results found that all treatments with propolis extract showed higher average viability than the control, which had average viability of 86.3%. Based on PDT (Population Doubling Time value), propolis extract has a good effect on brain cell growth, hence increasing cell proliferation. In addition, the confluent brain cells of rats given propolis extract had higher average confluency than those not given propolis extract. Propolis extract can protect neurons from damage by increasing the brain-derivatedneurotrophic factor (BDNF) gene expression in cell line neuron cultures. \u0000 ","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131363820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis Of Medicinal Plants On Embryo Development Of Mice (Mus Musculus L.) And White Rats (Rattus Novergicus): A Systematic Review 药用植物对小鼠胚胎发育的影响分析白鼠(Rattus Novergicus):系统综述

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-24 DOI: 10.58549/pcjn.v1i01.4

M. Mafruchati, J. Makuwira

引用次数: 0

TESTING THE EFFECTIVENESS OF BIDARA LEAF ETHANOL EXTRACT (Ziziphus mauritiana L.) IN GEL PREPARATIONS FOR BURN WOUNDS IN MALE RABBIT (Oryctolapus cuniculus) 比达拉叶乙醇提取物的药效测定公兔烧伤创面凝胶制剂的研究

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-24 DOI: 10.58549/pcjn.v1i01.2

S. Sulasmi, A. Sanjaya, Sofia Elia Sari Bangun, Cucu Arum Dwi Cahaya

{"title":"TESTING THE EFFECTIVENESS OF BIDARA LEAF ETHANOL EXTRACT (Ziziphus mauritiana L.) IN GEL PREPARATIONS FOR BURN WOUNDS IN MALE RABBIT (Oryctolapus cuniculus)","authors":"S. Sulasmi, A. Sanjaya, Sofia Elia Sari Bangun, Cucu Arum Dwi Cahaya","doi":"10.58549/pcjn.v1i01.2","DOIUrl":"https://doi.org/10.58549/pcjn.v1i01.2","url":null,"abstract":"Abstract \u0000Bidara plants have many benefits in the treatment of sore skin, ulcers, and burns. Burns are a form of tissue damage or loss caused by contact with a heat source such as fire, hot water, electricity, radiation, or corrosive substances. This study aims to determine the effectiveness of the ethanol extract of bidara leaf in healing burns in male rabbits compared to bioplacenta. This study used an experimental method of maceration extraction using 96% ethanol. To test the effect of burns, 15 test animals were grouped into five groups, each of which used three test animals. The treatment group was a gel-based negative control group, a positive bioplacenta control group, and a treatment group with bidara leaf ethanol extract at concentrations of 5%, 10%, and 15%. The results of the research on the effectiveness of healing burns in the three formulations, namely a concentration of 15%, showed faster healing of wound diameter in male rabbits compared to concentrations of 5% and 10% but were not more effective when compared to bioplacenta ointment. \u0000 \u0000Keywords: Bidara leaf ethanol extract, burns, ointment and bioplacenton","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"1994 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131148457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Embryo Development and Early Performance of Larvae of Barbonymus Schwanenfeldii: A Systematic Review 薛氏Barbonymus Schwanenfeldii幼虫胚胎发育及早期性能的系统分析

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-24 DOI: 10.58549/pcjn.v1i01.3

M. Mafruchati, J. Makuwira

{"title":"Analysis of Embryo Development and Early Performance of Larvae of Barbonymus Schwanenfeldii: A Systematic Review","authors":"M. Mafruchati, J. Makuwira","doi":"10.58549/pcjn.v1i01.3","DOIUrl":"https://doi.org/10.58549/pcjn.v1i01.3","url":null,"abstract":"Tengadak fish is a freshwater fish that can be found in rivers, lakes and canals and ditches. One of the important phases in fish development is the embryo. Embryo development (embryogenesis) is more in the process of formation and development of the embryo, not only the increase in the number and mass of embryonic blastomer cells but also the activity of blastomeric cells.The purpose of this study was to analyze the stages of embryonic development and early larval performance in Tengadak fish (Barbonymus schwanenfeldii). This study used systematic literature review using data from PubMed, NCBI, Google Scholar databases using keywords, namely, “embryo, performance, Tengadak fish (Barbonymus schwanenfeldii)”. Approximately, 350 articles were obtained for the keywords “embryo, performance, Tengadak fish (Barbonymus schwanenfeldii)”. All articles were selected based on inclusion criteria and exclusion and obtained as many as 27 articles that meet the inclusion criteria From the results of research conducted, it can be concluded that this research has sequentially described the embryonic development and early performance of the larvae of the barbonymus schwanenfeldii. Need research on the other animal for future research.","PeriodicalId":322289,"journal":{"name":"PCJN Pharmaceutical and Clinical Journal of Nusantara","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121624093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Activity of Staphylococcus capitis, Bacillus cereus, Pantoea dispersa From Telang Flower (Clitoria ternatea L) Kombucha Bath Soap as a Pharmaceutical Biotechnology Product 药用生物技术产品特朗花康普茶皂对头炎葡萄球菌、蜡样芽孢杆菌、分散泛菌的抑菌活性研究

PCJN Pharmaceutical and Clinical Journal of Nusantara Pub Date : 2022-11-24 DOI: 10.58549/pcjn.v1i01.1

Yuliana Kolo, Firman Rezaldi, M. Fadillah, Aris Ma'ruf, Fernanda Desmak Pertiwi, F. Hidayanto

引用次数: 4