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A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY最新文献

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The Importance of Lung Microenvironment on Gremlin1 Regulation and Pulmonary Fibrosis Pathogenesis 肺微环境对Gremlin1调控及肺纤维化发病机制的重要性
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2315
Q. Zhou, T. Yanagihara, K. Tsubouchi, W. Shi, S. Revill, A. Noble, A. Dvorkin-Gheva, J. Gauldie, K. Ask, M. Kolb
{"title":"The Importance of Lung Microenvironment on Gremlin1 Regulation and Pulmonary Fibrosis Pathogenesis","authors":"Q. Zhou, T. Yanagihara, K. Tsubouchi, W. Shi, S. Revill, A. Noble, A. Dvorkin-Gheva, J. Gauldie, K. Ask, M. Kolb","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2315","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2315","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115583726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibronectin-EDA Accumulates via Reduced Ubiquitination and Lysosomal Degradation in Scleroderma Lung Fibroblasts Downstream of Toll Like Receptor 9 Activation 在Toll样受体9激活下游的硬皮病肺成纤维细胞中，纤维连接素- eda通过泛素化和溶酶体降解的减少而积累
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2304
J. Evankovich, F. Tuncer, M. Bulik, J. Villandre, T. Lear, D. Kass, E. Valenzi, R. Lafyatis, B. Chen
{"title":"Fibronectin-EDA Accumulates via Reduced Ubiquitination and Lysosomal Degradation in Scleroderma Lung Fibroblasts Downstream of Toll Like Receptor 9 Activation","authors":"J. Evankovich, F. Tuncer, M. Bulik, J. Villandre, T. Lear, D. Kass, E. Valenzi, R. Lafyatis, B. Chen","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2304","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2304","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123719250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increases in Glutathione Dependent Protein Oxidation Impair Airway Basal Cell Differentiation 谷胱甘肽依赖蛋白氧化的增加损害气道基底细胞分化
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2312
E. Corteselli, J. Druso, C. Erickson, R. Aboushousha, M. MacPherson, Y. Janssen-Heininger
{"title":"Increases in Glutathione Dependent Protein Oxidation Impair Airway Basal Cell Differentiation","authors":"E. Corteselli, J. Druso, C. Erickson, R. Aboushousha, M. MacPherson, Y. Janssen-Heininger","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2312","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2312","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124004365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interleukin-11 Perpetuates a Vicious Cycle of Lung Macrophage and Mesenchymal Cell Activation in IPF 白细胞介素-11在IPF中维持肺巨噬细胞和间充质细胞活化的恶性循环
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2317
M. Hohmann, S. Garcia, M. Espíndola, B. Creyns, A. Coelho, T. Jun, D. King, J. Swaney, C. Hogaboam
{"title":"Interleukin-11 Perpetuates a Vicious Cycle of Lung Macrophage and Mesenchymal Cell Activation in IPF","authors":"M. Hohmann, S. Garcia, M. Espíndola, B. Creyns, A. Coelho, T. Jun, D. King, J. Swaney, C. Hogaboam","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2317","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2317","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132959188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GPR87 - a G-Coupled Protein Receptor Overexpressed in Human and Murine Pulmonary Fibrosis, Localizes to Aberrant Basaloid Cells in the IPF Lung GPR87 -一种在人和鼠肺纤维化中过表达的g偶联蛋白受体，定位于IPF肺中的异常基底样细胞
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2325
J. Khoury, F. Ahangari, T. Barnthaler, J. Mcdonough, N. Kothapalli, T. Adams, J. Schupp, G. DeIuliis, J. L. Gómez, N. Kaminski
{"title":"GPR87 - a G-Coupled Protein Receptor Overexpressed in Human and Murine Pulmonary Fibrosis, Localizes to Aberrant Basaloid Cells in the IPF Lung","authors":"J. Khoury, F. Ahangari, T. Barnthaler, J. Mcdonough, N. Kothapalli, T. Adams, J. Schupp, G. DeIuliis, J. L. Gómez, N. Kaminski","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2325","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2325","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121624065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of Lung Endothelial Cell Heterogeneity in Idiopathic Pulmonary Fibrosis (IPF) 特发性肺纤维化(IPF)患者肺内皮细胞异质性的研究
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2313
J. Lee, T.X. Pham, N. Caporarello, S.K. Huang, G. Ligresti
{"title":"Characterization of Lung Endothelial Cell Heterogeneity in Idiopathic Pulmonary Fibrosis (IPF)","authors":"J. Lee, T.X. Pham, N. Caporarello, S.K. Huang, G. Ligresti","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2313","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2313","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129270666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging CD38通过促进肺泡上皮细胞衰老介导肺纤维化
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2310
G. Liu, H. Cui, N. Xie, S. Banerjee, R-m Liu, V. Antony, Y. Sanders, V. Thannickal, N. Kaminski
{"title":"CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging","authors":"G. Liu, H. Cui, N. Xie, S. Banerjee, R-m Liu, V. Antony, Y. Sanders, V. Thannickal, N. Kaminski","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2310","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2310","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129415382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Peptidylarginine Deiminase-2 Is Highly Expressed in Rheumatoid Arthritis-Associated Interstitial Lung Disease Derived Lung Fibroblasts and Contributes to Their Profibrotic Phenotype 肽精氨酸脱亚胺酶-2在类风湿关节炎相关间质性肺疾病衍生的肺成纤维细胞中高表达并有助于其纤维化表型
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2305
K. Tsoyi, R. Bowen, X. Liang, F. Poli, R.E. Cardenas Castillo, S. Ryter, F. Romero, L. Celada, M. Robertson, M. Perrella, I. Ho, I. Rosas
{"title":"Peptidylarginine Deiminase-2 Is Highly Expressed in Rheumatoid Arthritis-Associated Interstitial Lung Disease Derived Lung Fibroblasts and Contributes to Their Profibrotic Phenotype","authors":"K. Tsoyi, R. Bowen, X. Liang, F. Poli, R.E. Cardenas Castillo, S. Ryter, F. Romero, L. Celada, M. Robertson, M. Perrella, I. Ho, I. Rosas","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2305","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2305","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121824251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
S100A4 Regulates Fibrotic Response Through Modulation of Matrix Expression S100A4通过调节基质表达调控纤维化反应
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2321
S. Li, M. Li, P. Fang, Y. Chang, Q. Ding, P. Che
{"title":"S100A4 Regulates Fibrotic Response Through Modulation of Matrix Expression","authors":"S. Li, M. Li, P. Fang, Y. Chang, Q. Ding, P. Che","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2321","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2321","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123400586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caveolin Scaffolding Domain LTI-03 Modulates Both Inflammatory and Fibrotic Responses in Aged Mice After Bleomycin Challenge 小窝蛋白支架结构域LTI-03调节衰老小鼠博来霉素刺激后的炎症和纤维化反应
A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2307
B. Mackenzie, E. Maier, B. Creyns, A. Coelho, B. Windsor, C. Hogaboam
{"title":"Caveolin Scaffolding Domain LTI-03 Modulates Both Inflammatory and Fibrotic Responses in Aged Mice After Bleomycin Challenge","authors":"B. Mackenzie, E. Maier, B. Creyns, A. Coelho, B. Windsor, C. Hogaboam","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2307","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2307","url":null,"abstract":"","PeriodicalId":302729,"journal":{"name":"A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116443714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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