World Journal of Cancer Research最新文献

{"title":"Application of Precise Positioning of Preoperative Ultrasound-Guided Carbon Nanoparticles in Thyroidmicrolesion Resection","authors":"波 于","doi":"10.12677/wjcr.2022.124029","DOIUrl":"https://doi.org/10.12677/wjcr.2022.124029","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123807928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Diagnosis and Treatment of a Case of Giant Renal Lipoma","authors":"昊 吴","doi":"10.12677/wjcr.2023.132010","DOIUrl":"https://doi.org/10.12677/wjcr.2023.132010","url":null,"abstract":"Renal lipoma is a rare benign tumor of the renal solid. Its interior is normal mature adipocytes, and its appearance is an expansive mass. Generally, there is no capsule, growth is slow, the course of disease is long, and the clinical symptoms are not obvious and typical. Often, the corresponding symptoms occur due to the compression of adjacent organs by larger masses. Tumors originate from adipocytes and can occur in the renal parenchyma, as well as in the renal tubules, pelvis, and","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125771806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinformatics Analysis of Genes Related to Liver Metastasis of Colorectal Cancer","authors":"义莲 黄","doi":"10.12677/wjcr.2023.133017","DOIUrl":"https://doi.org/10.12677/wjcr.2023.133017","url":null,"abstract":"Purpose: To find the key genes and therapeutic targets of liver metastasis of colorectal cancer (CRC) by mining and analyzing the existing gene expression data and related clinical data in the GEO database of the National Biotechnology Information Center (NCBI). Methods: The GEO database was searched, and the gene chips containing normal colorectal, CRC and liver metastatic tissues of CRC were screened. GEO2R tool was used to screen the differentially expressed genes (DEGs) between CRC and normal colorectal tissues and between CRC and liver metastasis of CRC, and the common DEGs of the two gene sets were further screened. Annotation, Visualization and Integrated Discovery Database (DAVID) was used for Gene Ontology (GO) analysis and Kyoto Encyclopedia of Gene and Genome (KEGG) pathway analysis. STRING database and Cytoscape software were used to construct Protein-Protein Interaction (PPI) network and screen Hub genes. The expression of Hub genes in normal colorectal, CRC and liver metastatic tissues of CRC was analyzed by R language, and the correlation between Hub genes and the prognosis of CRC was analyzed by Gene Expression Profile Interactive Analysis (GEPIA) database. Results: The gene chip GSE49355 showed that there were 1394 genes in CRC and normal colorectal tissues, 125 genes in CRC and liver metastasis of CRC, and 29 DEGs in the two gene sets. GO analysis showed that their biological processes may be mainly concentrated in complement activation, positive regulation of polypeptidase activity, alternative pathway. Cellular components were mainly located in blood particles and peripheral cells. Molecular functions were enriched in peptidase activator activity, CXCR chemokine receptor binding, extra-cellular matrix binding and chemokine activity. The enrichment analysis of KEGG signal pathway showed that DEGs were mainly enriched in complement and coagulation cascade, IL-17 signal pathway and TNF signal pathway. According to the sequence of related genes in PPI analysis, the first five Hub genes were SPP1, MMP1, MMP3, CXCL1 and CXCL5. Their expression in CRC was higher than that in normal colorectal tissues. The expression of SPP1 was gradually increased in normal colorectal, CRC and liver metastatic cancer, and the high expression of SPP1 was significantly correlated with poor survival in patients with CRC. Conclusion: CRC liver metastasis is related to SPP1, MMP1, MMP3, CXCL1 and CXCL5, which may provide a basis for further research on the molecular mechanism of CRC liver metastasis.","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131121551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 6 MV and 10 MV Flattening Filter-Free X-Ray Beams on Intensity Modulated Radiotherapy for Rectal Cancer","authors":"圣贤 彭","doi":"10.12677/wjcr.2022.123017","DOIUrl":"https://doi.org/10.12677/wjcr.2022.123017","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123746107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of PI3K/Akt/mTOR Pathway in Ovarian Cancer","authors":"乐 张","doi":"10.12677/wjcr.2022.123027","DOIUrl":"https://doi.org/10.12677/wjcr.2022.123027","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126485520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress of Endoplasmic Reticulum Stress in Hepatocellular Carcinoma","authors":"佳怡 徐","doi":"10.12677/wjcr.2023.132005","DOIUrl":"https://doi.org/10.12677/wjcr.2023.132005","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122057002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Advances of Prognostic Risk Factors of Wilms Tumor","authors":"建宇 汪","doi":"10.12677/wjcr.2023.132008","DOIUrl":"https://doi.org/10.12677/wjcr.2023.132008","url":null,"abstract":"Wilms tumor is the most common renal malignant tumor in children and it often needs systematic comprehensive treatment of surgery combined with radiotherapy and chemotherapy. Thanks to","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114891348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress of Cancer Trimodal Prehabilitation","authors":"义 李","doi":"10.12677/wjcr.2023.133015","DOIUrl":"https://doi.org/10.12677/wjcr.2023.133015","url":null,"abstract":"This paper introduces the development of cancer prehabilitation, discusses the necessity of the application of trimodal prehabilitation in cancer patients, and analyzes the specific aspects of exercise, nutrition and psychological aspects of trimodal","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114458651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect Comparison between Microwave Ablation and Thyroid Removal via Lateral Cervical Surgery for Benign Thyroid Nodules in Old Patients","authors":"传盛 杨","doi":"10.12677/wjcr.2021.113012","DOIUrl":"https://doi.org/10.12677/wjcr.2021.113012","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126506286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Peripheral Blood Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Assessing the Prognosis of Children with Hepatoblastoma","authors":"立玲 韩","doi":"10.12677/wjcr.2022.123013","DOIUrl":"https://doi.org/10.12677/wjcr.2022.123013","url":null,"abstract":"","PeriodicalId":286101,"journal":{"name":"World Journal of Cancer Research","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132251666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}