Vascular Malformations of the Central Nervous System最新文献

Blister Aneurysms 泡动脉瘤

Vascular Malformations of the Central Nervous System Pub Date : 2020-03-11 DOI: 10.5772/intechopen.89284

Themistoklis I. Papasilekas, Konstantinos M. Themistoklis, Stefanos I. Korfias, Damianos E. Sakas

引用次数: 0

Cerebral Arteriovenous Malformations (cAVMs): What Is New? 脑动静脉畸形(cavm):有什么新发现?

Vascular Malformations of the Central Nervous System Pub Date : 2019-12-13 DOI: 10.5772/intechopen.90096

A. Ganaw, Abdulgafoor M. Tharayil, Moad Ehfeda, Mohamed Hassan Alfared, Qazi Zeeshan, Sohel Mohamed Gamal Ahmed, A. Ayyad, Ibrahim Naemi, Hossam Algallie, Nissar Shaikh, N. Shallik

引用次数: 1

Intensive Care Management in Cerebral Aneurysm and Arteriovenous Malformations 脑动脉瘤和动静脉畸形的重症监护管理

Vascular Malformations of the Central Nervous System Pub Date : 2019-11-27 DOI: 10.5772/intechopen.89714

Sedef Tavukçu Özkan

引用次数: 0

Arteriovenous Fistulas: The Pathological Bridge 动静脉瘘:病理桥梁

Vascular Malformations of the Central Nervous System Pub Date : 2019-10-29 DOI: 10.5772/intechopen.89724

Sara A. AbuSini, Nour A. Tashtush, Abdelwahab J. Aleshawi, Amer Jaradat

引用次数: 0

Endovascular Treatment of Cerebral Arteriovenous Malformations 脑动静脉畸形的血管内治疗

Vascular Malformations of the Central Nervous System Pub Date : 2019-10-22 DOI: 10.5772/intechopen.89185

C. Senturk

{"title":"Endovascular Treatment of Cerebral Arteriovenous Malformations","authors":"C. Senturk","doi":"10.5772/intechopen.89185","DOIUrl":"https://doi.org/10.5772/intechopen.89185","url":null,"abstract":"Arteriovenous malformations (AVM) are vascular malformations composed of a network of abnormal vessels connecting directly between the artery and vein without an intervening capillary bed. Cerebral arteriovenous malformations have an incidence of 0.8–1.3 per 100.000 person years. Clinical symptoms include intracranial hemorrhage, seizure, headache, and focal neurological deficit. Annual mortality rate associated with hemorrhage is 1–5%, and 10–30% of survivors will have disability. Treatment options for cerebral AVMs include open surgery, embolization, and radiosurgery. Depending on the grade and angioarchitectural characteristics, a combination of these modalities can be used. Endovascular treatment can be performed for size and grade reduction, presurgical devascularization, size reduction before radiosurgery, targeted embolization, and as stand-alone treatment for cure. Targeted embolization can address intranidal or flow-related aneurysms and high flow arteriovenous shunts. Complications of the endovascular treatment include hemorrhage related to vessel perforation or normal pressure breakthrough phenomenon, ischemia, microcatheter retention, and other general complications associated with angiographic procedures. Mortality associated with endovascular treatment is less than 2% and permanent neurological deficit can be seen up to 2–8.9% of cases. New endovascular techniques include balloon-assisted embolization, transvenous embolization, and double microcatheter techniques like pressure cooker technique.","PeriodicalId":260013,"journal":{"name":"Vascular Malformations of the Central Nervous System","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116457546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Advocating Intraluminal Radiation Therapy in Cerebral Arteriovenous Malformation Treatment 提倡腔内放射治疗脑动静脉畸形

Vascular Malformations of the Central Nervous System Pub Date : 2019-10-17 DOI: 10.5772/intechopen.89662

N. Hirsh, A. Arthur, S. Golan

{"title":"Advocating Intraluminal Radiation Therapy in Cerebral Arteriovenous Malformation Treatment","authors":"N. Hirsh, A. Arthur, S. Golan","doi":"10.5772/intechopen.89662","DOIUrl":"https://doi.org/10.5772/intechopen.89662","url":null,"abstract":"In 2014, ARUBA (a randomized trial on cerebral Arteriovenous Malformation – AVM) found patients treated using prevalent interventional strategies are three times more likely to suffer a stroke/die compared with those treated conserva-tively (blood pressure reduction). Subsequent controversy led the European societies dealing with AVM to organize a consensus conference. Among the statements made was: “There may be indications for treating patients with higher Spetzler-Martin (SM) grades, based on a case-to-case consensus decision of the experienced team”. Thus, a clear accord emerges. There is a lacuna/weakness of interventional modalities when addressing high SM grade AVMs. This lack of a clear treatment choice originated our review. We attempt to identify the advantages and challenges of each present treatment/evaluation modality and highlight core requirements for future strategies. We conclude that existing modalities provide substantial recent improvements, yet the core challenge persists. Finally, we advocate testing a novel modality – intraluminal radiotherapy (active implants) by exploiting the “candy wrapper” or edge effect. If proven effective, this approach could offer gradual vessel occlusion with minimal abrupt hemodynamic changes known to induce hemorrhage, the lowest recurring session number (reduced costs), minimally invasive attributes and very low radiation (dose/dose rate) kinetics minimizing potential Adverse Radiation Effects (AREs).","PeriodicalId":260013,"journal":{"name":"Vascular Malformations of the Central Nervous System","volume":"84 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114011475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Spontaneous Spinal Epidural Haematomas 自发性脊髓硬膜外血肿

Vascular Malformations of the Central Nervous System Pub Date : 2019-09-19 DOI: 10.5772/intechopen.89175

David C. Kieser, Scheherezade Soltani, Michael C Wyatt, Khoon S. Lim, S. Kieser

引用次数: 9

Moyamoya Disease: A Rare Vascular Disease of the CNS 烟雾病:一种罕见的中枢神经系统血管疾病

Vascular Malformations of the Central Nervous System Pub Date : 2019-08-20 DOI: 10.5772/INTECHOPEN.88770

Abdulgafoor M. Tharayil, A. Ganaw, Nissar Shaikh, S. Prabhakaran, Arshad H. Chanda, S. Praveen, Ajith Kumar Choran, Qazi Sami ul Haq

{"title":"Moyamoya Disease: A Rare Vascular Disease of the CNS","authors":"Abdulgafoor M. Tharayil, A. Ganaw, Nissar Shaikh, S. Prabhakaran, Arshad H. Chanda, S. Praveen, Ajith Kumar Choran, Qazi Sami ul Haq","doi":"10.5772/INTECHOPEN.88770","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.88770","url":null,"abstract":"Moyamoya disease (MMD) is a rare disease affecting the cerebral vasculature of the central nervous system (CNS) with a reported incidence of 0.35–0.94 per 100,000 populations. It was first reported from Japan and later from other parts of the world. The pathology is narrowing of blood vessels supplying anterior circulation and rarely posterior circulation. It was believed that the disease is genetic in origin, but environmental factors also play a role. Patients with this rare disease may present with ischemic or hemorrhagic symptoms. Ischemic symptoms account for the disease in most of the pediatric patients, whereas in adults, hemorrhage is more common. Diagnostic imaging like CT angiogram and magnetic resonance angiogram helps in demonstrating the narrowing or the collateral vessels like “a puff of smoke” (moyamoya) formed at the base of the brain. Moyamoya disease is treated medically and/or surgically. Aspirin is the main medication used. Surgical options are direct or indirect revascularization techniques to bypass the stenosis. The disease is progressive in majority of the patients, but if treated early, they can have good prognosis especially children.","PeriodicalId":260013,"journal":{"name":"Vascular Malformations of the Central Nervous System","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115843607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Cerebral Arteriovenous Malformation from Classification to the Management 脑动静脉畸形从分类到治疗

Vascular Malformations of the Central Nervous System Pub Date : 2019-06-08 DOI: 10.5772/INTECHOPEN.86659

Nissar Shaikh, Aisha Al-Kubaisi, Muhammad Mohsin khan, Adnan Khan, Zia Mahmood, Arshad H. Chanda, A. Ganaw, Gamal Al-ameri, M. Rezk, Moad Ehfeda, M. Zubair, Jazib Hassan, AR Raju Vegesna

引用次数: 2