Europasian Journal of Medical Sciences最新文献

{"title":"Covering Letter","authors":"Ejms Journals","doi":"10.46405/ejms.v1i1.151","DOIUrl":"https://doi.org/10.46405/ejms.v1i1.151","url":null,"abstract":"COvering Letter","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123072160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Citation Style","authors":"Ejms Journals","doi":"10.46405/ejms.v1i1.155","DOIUrl":"https://doi.org/10.46405/ejms.v1i1.155","url":null,"abstract":"Citation Style","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116738089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicity Profiles of Commonly Used Anti-Inflammatory Drugs in Geriatrics","authors":"Talal Alhouzani, Mohammad Saleem, S. Khadka, Saleh Musaed Mohammed Al-Subari, D. Shrestha, Imamah Anwar Butt","doi":"10.46405/ejms.v2i2.107","DOIUrl":"https://doi.org/10.46405/ejms.v2i2.107","url":null,"abstract":"Anti-inflammatory drugs are among the mostly used drugs in geriatrics. Geriatrics usually encounter problems of pain and inflammation and are more vulnerable to the toxicity of drugs as compared to young patients. In this review, we aimed to find out the toxic profile of drugs and the pharmacotherapy considerations for geriatric care. The diseases geriatrics mostly suffered from are osteoarthritis (OA), ankylosing spondylitis, carcinoma, and other degenerative disorders that require anti-inflammatory medicines. Non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids are mostly used agents for the treatment of inflammation in geriatrics. Due to the over the counter (OTC) availability, NSAIDs are mostly used and being self-medicated as well. As the pharmacokinetics of drugs get altered due to alteration in body physiology in geriatrics, the pharmacodynamics also gets affected, and hence toxicity ensues even with normal dose. Depending upon the nature of the drugs; gastrointestinal, renal, and cardiovascular toxicities occur. Due to this reason, utmost care should be taken for pharmacotherapy practice in such population. The presence of comorbidity and poly-pharmacy will complicate drug therapy. The drugs should be used for the shortest duration possible at the lowest effective dose, and with careful surveillance to monitor toxicities. The careful evaluation of the beneficial and potential risks of the agents must be considered for pharmacotherapy practice in such populations.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126179983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge regarding COVID-19 among Registered Nurses of Pokhara, Nepal","authors":"Akriti Kafle, Sirjana Pandit Pahari, S. Khanal, Kushalata Baral, Kabita Pathak, S. Baral, Anil Kafle, Maginsh Dahal","doi":"10.46405/ejms.v2i2.88","DOIUrl":"https://doi.org/10.46405/ejms.v2i2.88","url":null,"abstract":"Background: Coronavirus disease is an emerging pandemic disease. The whole world is suffering from this disease these days. It is an acute respiratory disease in which transmission occurs essentially through respiratory droplets and this virus said to have 2-14 days of incubation.Objective: To assess their knowledge regarding COVID19 among registered nurses of Pokhara valley.Methods: A descriptive cross-sectional study was performed with the help of the pretested and self-administered questionnaires to 750 registered nurses of Pokhara valley. Thus collected data was entered into SPSS version 20 and then further analyzed using R software. Frequency, percentages, the mean and standard deviation were calculated for the analysis. p-value was calculated where ever applicable to find the significance of data.Results: The study disclosed that mass of the respondents had moderate proportion (44.8%) concerning understanding, followed by the respondents had a low level of knowledge (29.2%) and the rest of them (26.0%) had good knowledge about COVID 19.Conclusion: Overall knowledge among nurses was found to be satisfactory as the disease is entirely new. Further research and updates on the diseases will help to profound knowledge among nurses.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116469153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Access to Maternal Health Services during COVID-19","authors":"S. Pant, Saugat Koirala, M. Subedi","doi":"10.46405/ejms.v2i2.110","DOIUrl":"https://doi.org/10.46405/ejms.v2i2.110","url":null,"abstract":"Most causes of maternal morbidity and mortality can be prevented by giving prompt, suitable treatment to the women by qualified health practitioners. Maternal health services (MHS), which include antenatal care, delivery care, and postnatal care, can play a crucial role in preventing maternal health problems. The recent coronavirus disease (COVID-19) pandemic has had a disastrous effect on the health care delivery system of people of all ages, on a global scale but pregnant women face particular challenges. The aim of this review is to assess the effect of COVID-19 on access to MHS. For writing this narrative review, national and international reports on maternal health services during COVID-19, along with journal articles on the related topic were reviewed. Due to this pandemic, women worldwide are facing more barriers to accessing maternal health care, including restrictions, transport challenges, and anxiety over possibly being exposed to coronavirus. Many women preferred not to seek healthcare due to the fear of themselves being infected with the virus or transmitting it to their unborn babies. Additionally, movement restriction has made it difficult for many pregnant women to reach health care facilities. Even those who managed to reach health facilities have reported not receiving timely care. As a result, a considerable rise in maternal mortality globally has been estimated over the next six months. Despite the circumstances, efforts have been made to boost maternal health in both developed and developing countries. This pandemic has highlighted the importance of health preparedness with special attention given to vulnerable people like pregnant women and newborns while planning for such events.\u0000\u0000Keywords: Childbirth, COVID19, Maternal Health, Pandemic, Pregnancy, Women’s health","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123412050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydroxychloroquine with or without macrolide and standard of care versus standard of care alone for COVID-19 cases: a systematic review and meta-analysis","authors":"D. Shrestha, P. Budhathoki, S. Khadka, Era Rawal","doi":"10.21203/rs.3.rs-39092/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-39092/v1","url":null,"abstract":"\u0000 Background: Coronavirus disease (COVID-19) pandemic has been a global health threat. The specific treatment of this disease has not yet been approved. In this review, we aimed at assessing the role of hydroxychloroquine with/without macrolide in terms of efficacy and adverse effects against the standard of care. Methods: Pubmed, Medline, Google Scholar, Cochrane Library, and Clinicaltrials.gov were searched for the quantitative and qualitative synthesis of 13 studies using PRISMA guidelines for a proper review. Assessment of heterogeneity was done using the I-squared (I2) test and fixed/random effect analysis was done to determine the odds/risk ratio among the selected studies.Results: Meta-analysis of our study demonstrated no significant differences in improvement for the virological cure (RR 0.95, 0.67-1.34), whereas a significant relationship was there in radiological progression (pneumonia resolution) (RR 1.40, 1.03-1.91) between the two arms. There are 1.52 times the odds of intubation during treatment (CI 0.61-3.77), 1.08 times the risk of mortality (CI 0.65-1.79), and about 2.21 times increased risk of development of adverse effect (OR 2.21, 0.95-5.17). Though overall it is of no statistical significance, clinical relevance to thinking while using the treatment for COVID-19 is advised. Among randomized controlled trials, the treatment group has 3.5 times (OR 3.48, 1.64-7.42) higher risk of developing adverse effects. There is 2.5 times the likelihood of severe arrhythmias and QT prolongation (OR 2.49, 1.67-3.70) on the treatment arm compared to control.Conclusion: Hydroxychloroquine with/without macrolide has shown no beneficial effect in viral clearance, survival rates while shows significant relation with the radiological improvement compared to standard of care but may increase the risk of intubation, overall side effects, and cardiac complications like arrhythmias and QT prolongation. Thus utilizing this treatment needs to be judged in clinical relevance and proper monitoring.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128542605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Implications of COVID-19 in Kenya","authors":"Marylyn Ochillo, I. Elsie","doi":"10.46405/ejms.v2i2.111","DOIUrl":"https://doi.org/10.46405/ejms.v2i2.111","url":null,"abstract":"Dear Editor, \u0000As the COVID-19 pandemic continues to spread rapidly worldwide, it is certainly having an immense effect on the mental wellbeing of people thereby increasing the number of people with elevated levels of stress, depression, or anxiety.1 Developing countries will undoubtedly have serious mental health implications due to the poor or almost non-existent mental health services. \u0000In Kenya, mental health is still somewhat neglected mainly because only 0.05% of the Governments’s health budget allocation goes to mental health.2 The allocated health budget largely focuses on communicable diseases despite the impact of mental health on the Kenyan population. Although there are no accurate data on the prevalence of mental disorders in Kenya, various studies have shown that the prevalence of depression generally varies from 19% in household review studies2 to 42% among the general population visiting the health facilities.3 Similar to other African countries, Kenya has a shortage of mental health professionals. Mathari hospital is the country’s only mental referral facility where one nurse handles up to 150 patients.4 In a country with only approximately 100 psychiatrists serving a population of 45 million, only a third of the psychiatrists work in the government health facilities.5 The rest of the psychiatrists work in private health facilities that are generally more expensive making them inaccessible to the majority of the population due to the unaffordable consultation fees.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115579846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Concern during COVID-19 Pandemic in Nepal","authors":"A. Chalise, S. Paudel","doi":"10.46405/ejms.v2i2.87","DOIUrl":"https://doi.org/10.46405/ejms.v2i2.87","url":null,"abstract":"The whole world struggles to combat COVID-19 pandemic forcing nations to take extreme measures in an attempt to prevent outbreaks and save lives. It has been noted that COVID-19 has established itself as a risk factor for psychological distress among the population of different subgroups. There are several factors such as uncertainties, controversies, misinformation, social isolation, stigma, and discrimination which are escalating the risk of massive mental distress among the public. Nepal is trying to increase its effort to combat COVID-19 by adopting community containment measures, but the mental health of the frontline health workforce, service providers, and the general public seems to be highly overshadowed. In this aspect, this paper aims to shed light on different aspects of mental health issues emerging in Nepal during the time of COVID-19 lockdown, along with some of its potential contributing factors. Nepal lacks adequate infrastructure and human resource to provide mental healthcare services effectively in case of any massive mental distress. In this state of resource deprivation, providing education and training regarding psychosocial issues to health system leaders, first responders, and health care professionals could be a key to address the population need at present and to prevent further complications.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132711777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grammar and Spelling Checker","authors":"Europasian Journals","doi":"10.46405/ejms.v1i1.84","DOIUrl":"https://doi.org/10.46405/ejms.v1i1.84","url":null,"abstract":"Paste the contents here \u0000to check the grammar and spelling.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"398 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123270711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Pregnancy after Previous Uterine Rupture","authors":"K. Tiwari, A. Karki, G. Dangal, H. Pradhan, R. Shrestha, K. Bhattachan, Rekha Paudel, N. Bajracharya, S. Bharati","doi":"10.46405/ejms.v2i1.22","DOIUrl":"https://doi.org/10.46405/ejms.v2i1.22","url":null,"abstract":"Uterine rupture is a rare and catastrophic incidence with high maternal and fetal morbidity rates. It is most commonly seen in the scarred uterus. The unscarred uterus is least susceptible to rupture with the incidencebeing 1 in 8000 deliveries. In the past, pregnancy after uterine rupture was not widely advised and patients underwent hysterectomy or tubal ligation but with the evolving practice, women are motivated for pregnancy which can be successful with proper obstetric care and emphasis on time and mode of delivery. Here we present a case of 31 years old female, gravida-2 para-1 living 0 with previous uterine rupture after medical induction of labor with stillbirth 4 years ago. She underwent emergency laparotomy with the repair. The patient spontaneously conceived and had close antenatal care throughout the pregnancy. The patient was admitted at 34 weeks of gestation and kept under close surveillance. Corticosteroid was administered. She underwent spontaneous labor at 37 weeks of gestation and emergency cesarean section was planned, delivered via a breech presentation to a live baby of 2.4 kg, APGAR score of 8/10, 9/10 at 1 and 5 minutes.","PeriodicalId":254508,"journal":{"name":"Europasian Journal of Medical Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114733724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}