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Development of a potentiometric circuit for A PZR microcantilever biosensor for measurement of human stress 用于人体压力测量的PZR微悬臂生物传感器电位测量电路的研制
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742287
M. F. Abdullah, L. Khuan, Mohd Ismarul A. Ismail, A. Hamid, I. Rustam, Maureen S. A. Bujang, Norhairi Rusmani, N. K. Madzhi, A. Ahmad
{"title":"Development of a potentiometric circuit for A PZR microcantilever biosensor for measurement of human stress","authors":"M. F. Abdullah, L. Khuan, Mohd Ismarul A. Ismail, A. Hamid, I. Rustam, Maureen S. A. Bujang, Norhairi Rusmani, N. K. Madzhi, A. Ahmad","doi":"10.1109/IECBES.2010.5742287","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742287","url":null,"abstract":"This paper describes design and development of transduction, filtering, stabilisation and linearization stages of a potentiometric circuit to convert micro-signals from a PZR microcantilever biosensor into readable signals for human stress. The biosensing principle is based on immobilization of the bioreceptor to produce a biochemical reaction. The novel potentiometric circuit converts this biochemical event into a measurable electrical output. The transduction stage transforms the changes in enzymatic reaction in salivary alpha amylase, influenced by the level of human stress into resistivity within range of 1.2–1.3kΩ and corresponding potential of 108.6 to − 100mV. The subsequent stages condition the signal to attain an output of 0–5V. The design for filtering stage employs a first order high and low pass filter to capture stress signals, known with frequency of 0.15–0.4Hz. Performance of the circuit is evaluated with simulation and experimental study. On the average, discrepancy less than 3.69%, 4.5% and 3.7% is found between simulation and experimental results for the three stages of the circuit respectively.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125358887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Brain and heart interaction during sleep in the healthy and sleep apnoea 大脑和心脏在健康睡眠期间的相互作用和睡眠呼吸暂停
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742243
H. Abdullah, N. Maddage, I. Cosic, D. Cvetkovic
{"title":"Brain and heart interaction during sleep in the healthy and sleep apnoea","authors":"H. Abdullah, N. Maddage, I. Cosic, D. Cvetkovic","doi":"10.1109/IECBES.2010.5742243","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742243","url":null,"abstract":"Neurocardiology is a study of interaction between the brain and the heart. This paper presents the pilot study which assessed the multivariate analysis of EEG and ECG activity in the healthy and sleep apnoea patients during different sleep stages. Three synchronization measures based on a linear method (cross-correlation), information theory (mutual information) and nonlinear interdependence, were applied to analyse the EEG and ECG signals. The results indicated that the brain is dependent more on the heart electrical activity during different sleep stages and brain hemispheres in the healthy and sleeps apnoea. This might suggest that the information that flows from the heart, actually modulates the brain electrical activity or simply that heart drives the brain activity.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114732917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
User requirement analysis for personalized cancer dietary planning and menu construction 用户需求分析，个性化癌症饮食规划和菜单构建
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742272
F. A. Saludin, Nasriah Zakaria, W. Husain
{"title":"User requirement analysis for personalized cancer dietary planning and menu construction","authors":"F. A. Saludin, Nasriah Zakaria, W. Husain","doi":"10.1109/IECBES.2010.5742272","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742272","url":null,"abstract":"Cancer has been a major cause of death in Malaysia and total number of patients diagnosed is increasing each year. Based on anecdotes of cancer patients and survivors, we found that many patients and survivors do not seek for proper diet guidance and rely on their network for such information. Realizing the importance of proper diet to cancer patients, a personalized dietary planning and menu construction is proposed. The proposed system will offer information on dietary and nutritional tips, seven day meal plan and collection of healthy recipes. Research on user requirement of the system has been conducted in order to identify and analyze information regarding cancer patients' diet and nutritional that is useful to them. The outcome of this research is a complete list of user requirements for development of personalized cancer dietary planning and menu constructions. The result of the user requirements analysis is a web-based system that recommends tips, guidelines and meal plan for cancer patients. All recommendations are based on individual health information and current health status.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133883997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A better way for exon identification in DNA splicing 一种更好的DNA剪接外显子鉴定方法
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742274
Muneer Ahmad, A. Abdullah, Khalid A. Buragga
{"title":"A better way for exon identification in DNA splicing","authors":"Muneer Ahmad, A. Abdullah, Khalid A. Buragga","doi":"10.1109/IECBES.2010.5742274","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742274","url":null,"abstract":"The strands of chromosomes are supposed to be split into genic and intergenic regions. Gene identification is an optimization problem in Eukaryotic DNA splicing. An optimal solution is essential which may help in better protein translation. We have proposed a novel approach for gene identification by employing discrete wavelet transforms for noise reduction in DNA sequences and introducing a new indicator sequence for better signal generation. Wavelet transforms greatly reduced the background noise and visible peaks of genic regions were found in power spectral estimation. The comparative analysis of proposed and existing approaches showed significant results for novel approach over prevailing solutions over dataset Yersinia pestis (ACCESSION: NC_004088, 4000 bp, four genes and exons from location 5000 bp to 8999 bp). Similar outperformace was observed over many other datasets.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132027329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Classification of surface electromyographic signal using fuzzy logic for prosthesis control application 基于模糊逻辑的表面肌电信号分类在假肢控制中的应用
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742283
S. A. Ahmad, A. J. Ishak, S. Ali
{"title":"Classification of surface electromyographic signal using fuzzy logic for prosthesis control application","authors":"S. A. Ahmad, A. J. Ishak, S. Ali","doi":"10.1109/IECBES.2010.5742283","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742283","url":null,"abstract":"This paper describes the classification stage of an electromyographic (EMG) control system for prosthetic hand application. Moving ApEn was used as main method to extract features from the two channels of surface EMG signal at the forearm of the upper limb. A fuzzy logic system is used to classify the extracted information in discriminating the final grip posture. The results demonstrate the ability of the system to classify the information related to different grip postures.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130756465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Analysis and experiment of centrifugal force for microfluidic ELISA CD platform 微流控ELISA CD平台离心力分析与实验
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742282
F. Ibrahim, P. Jahanshahi, N. Abd Rahman, N. Soin, M. Madou, A. A. Nozari, N. Soin, K. A. Samra, Kameel Abi Samra
{"title":"Analysis and experiment of centrifugal force for microfluidic ELISA CD platform","authors":"F. Ibrahim, P. Jahanshahi, N. Abd Rahman, N. Soin, M. Madou, A. A. Nozari, N. Soin, K. A. Samra, Kameel Abi Samra","doi":"10.1109/IECBES.2010.5742282","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742282","url":null,"abstract":"This paper presents an analysis and experiment of centrifugal force for microfluidic Enzyme-Linked Immunosorbent Assay (ELISA) on a compact-disc (CD) platform. The ELISA CD was designed based on the centrifugal force as a driving force while capillary force acts as preventing barrier. The CD composed of 2 layers: the substrate layer is made of PMMA and the top layer is laminated with an Adhesive Sealing Films (ASF) or thermal seal. The PMMA substrate was fabricated by CNC micromachining. The ELISA CD consists of 7 reservoirs: waste, detection, serum, conjugate, washing solution, substrate and stopping solution. In the experiment, the reservoirs were filled with colour liquid and the fluid flow behaviour of the liquid in the CD was studied and monitored by a customized CD spin stand system equipped with visualization system. The experimental test results show an average of 9% error when compared with the theoretical calculation of burst frequency for all the reservoirs.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122035452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Analysis of genetic data in for implementation of compression algorithm in Alzheimer's Disease database 对遗传数据进行分析，实现阿尔茨海默病数据库的压缩算法
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742291
I. Yassin, H. Z. Abidin, R. Baharom, E. H. Mat Saat, A. Zabidi
{"title":"Analysis of genetic data in for implementation of compression algorithm in Alzheimer's Disease database","authors":"I. Yassin, H. Z. Abidin, R. Baharom, E. H. Mat Saat, A. Zabidi","doi":"10.1109/IECBES.2010.5742291","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742291","url":null,"abstract":"A database to store genetic information of Alzheimer's Disease (AD) patients is necessary to spur research in development of drugs suitable for local patients. Works by Abdul Rahman et. al. had created this database. However, the database contains large amounts of redundant genetic data. The storage of uncompressed data is suboptimal because it would consume large storage space as well as slow down transmissions over networks. In this paper, we propose the integration of compression algorithm into the AD genetic database to optimize its storage space. We describe our implementation as well as the results. The compression algorithm had managed to reduce the storage space of the AD database to 38.89% of the original storage space.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121381525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Biologically inspired circuit model for simulation of acetylcholine gated ion channels of the postsynaptic membrane at synaptic cleft 模拟突触间隙突触后膜乙酰胆碱门控离子通道的生物学启发电路模型
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742191
J. C. Dutta, Soumik Roy
{"title":"Biologically inspired circuit model for simulation of acetylcholine gated ion channels of the postsynaptic membrane at synaptic cleft","authors":"J. C. Dutta, Soumik Roy","doi":"10.1109/IECBES.2010.5742191","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742191","url":null,"abstract":"The variable conductance of postsynaptic membrane of neuron dependence on the acetylcholine-receptor binding activity is represented by enzyme modified field effect transistor (ENFET) sensitive to acetylcholine. Acetylcholine sensitive ENFET functions not only as a voltage controlled conductance but can also provide a means of measurement of specific neurotransmitters that bind with the receptor sites of postsynaptic membrane. This analog is incorporated into the famous Hodgkin-Huxley (H-H) model of neuron to substitute the variable Na+ conductance. Simulation is performed in MATLAB environment both for normal (excitatory) and pathologic states and results are presented.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126690028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Muscles activities at two different work area boundaries during sedentary work 久坐工作时两个不同工作区域边界的肌肉活动
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742263
N. M. Nur, S. Dawal
{"title":"Muscles activities at two different work area boundaries during sedentary work","authors":"N. M. Nur, S. Dawal","doi":"10.1109/IECBES.2010.5742263","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742263","url":null,"abstract":"The aim of this study is to investigate the effects on upper limb and lower back muscles activities at two different work area boundaries during sedentary work. Subjects consisted of 10 males (age 27.7±5.42) and 10 females (age 27.5±5.91) with no history of musculoskeletal injury or back problem at the time of participation. Surface electromyography (EMG) signal were recorded from the right and left Levator Scapulae, Upper Trapezius, Anterior Deltoid and Erector Spinae which are known as the weaken and tighten muscles due to musculoskeletal disorders (MSD). The EMG signal was processed and normalized in the form of % MVC for analysis. The overall results indicated that the upper limb and lower back muscles activities increased significantly when performing work at the far boundary work area. The muscle activity at the far boundary work area is averagely 17% greater than at the near boundary work area. The result of independent sample t-test showed that the gender effects found to be significant at the far boundary work area.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116743279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A preliminary study on autonomic nervous system assessment during aerobic exercise using TEMPV 用TEMPV评价有氧运动中自主神经系统的初步研究
2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES) Pub Date : 2010-11-01 DOI: 10.1109/IECBES.2010.5742240
Jae Hoon Jung, Yeonsik Noh, Young Myeon Han, Min Yong Kim, U. Yoon, I. Hwang, H. Yoon, I. Jeong
{"title":"A preliminary study on autonomic nervous system assessment during aerobic exercise using TEMPV","authors":"Jae Hoon Jung, Yeonsik Noh, Young Myeon Han, Min Yong Kim, U. Yoon, I. Hwang, H. Yoon, I. Jeong","doi":"10.1109/IECBES.2010.5742240","DOIUrl":"https://doi.org/10.1109/IECBES.2010.5742240","url":null,"abstract":"The purpose of this study is to monitor the autonomic nervous system with average skin temperature and its variability, of which both are compared with heart rate variability. Six healthy male college students participated in a test which is composed of rest for 5 min., exercise for 20 min. and recovery for 10 min. to measure their ECG and skin temperature with BIOPACK. The test found similarity between HRV's total power and peak amplitude of skin temperature variability towards physical stress. Furthermore, the constant fall of mean temperature during exercise and recovery capacity during recovery stage also proved that subjects differ in their autonomic nervous system activities to maintain homeostasis.","PeriodicalId":241343,"journal":{"name":"2010 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115737459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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