Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology最新文献_第8页

[Microbiologic diagnosis of meningitis. Commission for the Establishment of Guideline Procedures for Microbiologic Diagnosis]. 脑膜炎的微生物学诊断。微生物学诊断指南程序制定委员会]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-08-01

引用次数: 0

[Metabolism of phosphate-limited Streptomyces cultures. III. The ambivalent effect of phosphates in nourseothricin-producing cultures of Streptomyces noursei JA 3890b]. [磷酸盐限制链霉菌培养物的代谢]。3磷酸盐在产产诺氏链霉菌JA 3890b培养物中的矛盾效应[j]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-08-01

P J Müller, J H Ozegowski

{"title":"[Metabolism of phosphate-limited Streptomyces cultures. III. The ambivalent effect of phosphates in nourseothricin-producing cultures of Streptomyces noursei JA 3890b].","authors":"P J Müller, J H Ozegowski","doi":"","DOIUrl":"","url":null,"abstract":"A common condition in the evolution of organisms and their metabolism seems to be a latent lack of available phosphate in the natural environment. Accordingly, the phosphate dependent metabolisms of the soil-living streptomycetes should be stamped by lack of phosphate, too. The biosynthesis of the streptothricin antibiotic nourseothricin by Streptomyces noursei 3890b is initiated by limitation of soluble phosphate in the fermentation medium. At the other side is shown that a certain rate of feeding of phosphate during the fermentation increases the nourseothricin biosynthesis. An ambivalente role of phosphate on the secondary metabolite biosynthesis is stated. The limitation of phosphate leads to a special physiological state of the producer, characterized by secondary product formation and dephosphorylating activities in cells. This state is temporally stabilized by the presence of a sufficient phosphate supply, realized by enzymatic hydrolysis of complex phosphate-containing substrates or by a direct feeding of inorganic phosphate to the fermentations. The occurrence of different physiological states in respect to the phosphate-dependent metabolism is described by S-shaped functions of the relationship between specific growth rate and the phosphate concentration in the medium. The special behaviour of Streptomyces noursei cells at phosphate limitation is discussed to be the result of the dephosphorylating activities in cells, hydrolyzing phosphoester-bonds of regulatory metabolites as well as energy-rich compounds.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"260 1","pages":"15-34"},"PeriodicalIF":0.0,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14132311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective characteristics of the antigen common to Pseudomonas and Vibrio and significance of bacterial endotoxins in protection against selected bacterial infections. 假单胞菌和弧菌共同抗原的保护特性及细菌内毒素对特定细菌感染的保护意义。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-07-01

J Sourek

{"title":"Protective characteristics of the antigen common to Pseudomonas and Vibrio and significance of bacterial endotoxins in protection against selected bacterial infections.","authors":"J Sourek","doi":"","DOIUrl":"","url":null,"abstract":"The protective effect of different vaccines against the killing activity of Pseudomonas aeruginosa and Vibrio parahaemolyticus for mice was studied. Cross experiments confirmed the high protective effect of the Pseudomonas common antigen (original endotoxin protein) contained in Pseudomonas vaccine, which, together with other soluble components, substantial afforded protection of mice against vibrios and thus confirmed the antigenic relationship between Pseudomonas and Vibrio. Satisfactory results were also obtained by vaccination with selected bacterial endotoxin lipopolysaccharides derived from some members of the Enterobacteriaceae family, which in some cases afforded 70-90% and in others only a 20-50% protection against Pseudomonas and Vibrio infection. The protective effect was reduced by up to 2/3 was obtained with vaccines subjected to alkaline hydrolysis. A single dose of Propionibacterium parvum cells not followed by specific vaccination afforded up to 50% protection against challenge with P. aeruginosa or V. parahaemolyticus. Special characteristics of the vaccines studied and their protective effects in relation to some immunological aspects of nonspecific resistance are discussed.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"259 4","pages":"538-47"},"PeriodicalIF":0.0,"publicationDate":"1985-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13561022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Development of Salmonella resistance in the Vienna area 1980-1983]. [1980-1983年维也纳地区沙门氏菌耐药性的发展]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-07-01

D Stur, J Presslich

引用次数: 0

[Gnotobiotic studies on SPF mice in relation to a study of tumor development in the colon after cholecystectomy]. [在SPF级小鼠上的非甾体生物研究与胆囊切除术后结肠肿瘤发展的研究有关]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-05-01

E Haralambie, K Littmann, R Edenharder, G Linzenmeier

{"title":"[Gnotobiotic studies on SPF mice in relation to a study of tumor development in the colon after cholecystectomy].","authors":"E Haralambie, K Littmann, R Edenharder, G Linzenmeier","doi":"","DOIUrl":"","url":null,"abstract":"The relation between cholecystectomy and colon carcinogenesis has not been fully elucidated. As bacteria may be involved in the carcinogenic process, we investigated the effect of cholecystectomy and dimethylhydrazine (DMH) administration to SPF NMRI mice with regard to tumour genesis and bacterial colonisation of the intestine. It results from this study that cholecystectomy does not influence tumour genesis and that 6-7 months post operationem and DMH administration tumours and bacteria originally not found in the animals develop: clostridia, eubacteria spec. which cannot be differentiated and E. lentum. Theses changes appear in group II of mice (laparotomy and DMH) and group III (cholecystectomy and DMH), but not in group I (controls). From the results of this study we cannot conclude whether the tumours or the new bacteria appeared first. Biochemical investigations of C. innocuum, C. paraputrificum and C. tertium indicated that these bacteria metabolised bile acids by a specific metabolic step only but not produced carcinogenic substances themselves. If bacteria are involved in tumorgenesis, different species may be involved producing a carcinogenic environment by metabolic chain reactions. We know of such a bacterial collaboration in anaerobic infections.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"259 3","pages":"359-66"},"PeriodicalIF":0.0,"publicationDate":"1985-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14067514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Differentiation of clostridia]. [梭菌的分化]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-05-01

E R Niculescu, G Kottenhoff, R Malottke

{"title":"[Differentiation of clostridia].","authors":"E R Niculescu, G Kottenhoff, R Malottke","doi":"","DOIUrl":"","url":null,"abstract":"162 Clostridium strains (20 species), isolated from clinical specimens, were identified by their morphological, biochemical, and gaschromatographic characteristics. The reliability of the Api 20A system in identifying Clostridium species was studied by performing biochemical tests both in the microsystem and according to the VPI Anaerobic Handbook. 66% of the Clostridium strains could be identified by the Api 20A system supplemented, in accordance with the Api Handbook by other tests such as morphology, lipase and lecithinase production. The following Clostridium species, known as clinically most significant, could be identified by the Api 20A system: Clostridium sordellii and C. sporogenes (92%), C. bifermentans (60%) and C. tertium (78%). Methods which can be used in the clinical laboratory for the identification of Clostridium species are described, i.e. isolation of Clostridium strains from mixed cultures, examination of morphological characteristics, performance of biochemical tests in the Api 20 A system as a micromethod, verification by conventional biochemical test systems and gaschromatographic analysis in special laboratories if necessary.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"259 3","pages":"307-16"},"PeriodicalIF":0.0,"publicationDate":"1985-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15162304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Distribution of species of the genus Listeria]. [李斯特菌属的分布]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-05-01

J Rocourt, H P Seeliger

{"title":"[Distribution of species of the genus Listeria].","authors":"J Rocourt, H P Seeliger","doi":"","DOIUrl":"","url":null,"abstract":"Within the classification of different Listeria species according to present knowledge, this study investigates the sources and distribution of both the known \"classical\" species of Listeria as well as the recently added species: L. monocytogenes, L. innocua, L. ivanovii, L. welshimeri, L. seeligeri, L. grayi and L. murrayi. For this purpose 573 isolates from the environment, food, healthy carriers and patients suffering from listeriosis were selected out of a total of approximately 6000 strains originating from all parts of the globe which are maintained at the Listeria Culture Collection of the Institute of Hygiene, Würzburg. The selection was made according to the criterium of widest possible geographic distribution. The results indicate the environment to be the natural reservoir of all of the 7 'new' Listeria species. Healthy animal carriers harbour in their intestinal tract all species of Listeria with the exception of L. murrayi, whilst in the excreta of healthy individuals only the species L. monocytogenes, L. ivanovii, and L. innocua were found. Identification of strains from pathological specimens of human and animal origin resulted invariably in the finding of L. monocytogenes or L. ivanovii. L. grayi (7 strains) was found sporadically in Europe and in the USA, whereas L. murrayi (9 strains) has been isolated only in the USA. 26 of 28 so far known strains of L. welshimeri originated from the USA, and only 2 strains of this species were found in Europe. L. seeligeri (80 strains) was identified among European isolates, L. innocua, however, in both USA and Europe. L. ivanovii occurs in Australia, Europe and the USA. L. monocytogenes is of global distribution. Table 1 presents a survey of species, serovariety and origin of the 573 isolates. As both pathogenic and non pathogenic listeria strains are found in the human environment, it is necessary to identify each isolate appropriately, particularly in view of the elucidation of the rather obscure epidemiology of human listeriosis.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"259 3","pages":"317-30"},"PeriodicalIF":0.0,"publicationDate":"1985-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15162305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Immunity of the skin--infection and percutaneous immunization of rabbits with E. coli ATCC 13676]. [皮肤免疫——家兔ATCC 13676感染及经皮免疫]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-04-01

W Hammerschmidt, E Hellmann

{"title":"[Immunity of the skin--infection and percutaneous immunization of rabbits with E. coli ATCC 13676].","authors":"W Hammerschmidt, E Hellmann","doi":"","DOIUrl":"","url":null,"abstract":"After intracutaneous infection of rabbits with a suspension of E. coli which was followed by a transient local inflammation, the local and systemic immune responses were determined using the lymphocyte stimulation test (LTT) and the hemolysis plaque assay (HPA). Lymphocytes of the lymphatic system draining the infected skin area and blood lymphocytes were used. With lymphocytes derived from the local lymph nodes, a substantial increase of specific stimulation in the LTT was detected beginning at day 3 after infection and lasting up to the termination of the experiment (3 weeks). Blood lymphocytes were stimulated at a lower level: The activity showed a peak at day 4 and an elevated level only during a 10-day period. After the intracutaneous infection with E. coli, increasing numbers of antibody-releasing lymph node cells were detected in the HPA. The antibody-secreting cells of the IgM and IgG classes clearly showed an increasing specificity for E. coli lipopolysaccharide coupled to sheep red blood cells. As with the LTT, the highest activities (values of specificity and number of plaque-forming lymphocytes) were observed at the end of the experimental period. An emulsified preparation of a heat-inactivated E. coli culture (E. coli-BKS) which had been applied locally onto the artificially altered skin evoked a similar immunological response after a 2 or 3-weeks treatment. In such animals an increased activity of lymph node cells could be registered by LTT and HPA as compared to reactions from placebo-treated control animals. However, the topical immunization with nonviable E. coli stimulated not only lymphocytes which produced antibodies directed specifically against E. coli lipopolysaccharide as demonstrated by the HPA. An increased number of lymphocytes reacted even with native sheep red blood cells. This observations is discussed in respect of a polyclonal B-cell activation by lipopolysaccharide of the E. coli-BKS.","PeriodicalId":23821,"journal":{"name":"Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology","volume":"259 2","pages":"252-67"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15007549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Time requirements for positive blood cultures with reference to different methods of determining bacteria in blood cultures]. [参考血液培养中不同细菌测定方法的阳性血培养时间要求]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-04-01

R Küchler

引用次数: 0

[Hyalurodinase activity of beta-hemolytic streptococci of the Lancefield group C]. [Lancefield组溶血性链球菌透明质酸酶活性研究]。

Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology Pub Date : 1985-04-01

E Balke, R Weiss, A Seipp

引用次数: 0